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Results: 1 to 20 of 105

1.

Mechanistic and structural analyses of the role of His67 in the yeast polyamine oxidase Fms1.

Adachi MS, Taylor AB, Hart PJ, Fitzpatrick PF.

Biochemistry. 2012 Jun 19;51(24):4888-97. doi: 10.1021/bi300517s. Epub 2012 Jun 5.

PMID:
22642831
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanistic and structural analyses of the roles of active site residues in yeast polyamine oxidase Fms1: characterization of the N195A and D94N enzymes.

Adachi MS, Taylor AB, Hart PJ, Fitzpatrick PF.

Biochemistry. 2012 Oct 30;51(43):8690-7. doi: 10.1021/bi3011434. Epub 2012 Oct 15.

PMID:
23034052
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mechanistic studies of the yeast polyamine oxidase Fms1: kinetic mechanism, substrate specificity, and pH dependence.

Adachi MS, Torres JM, Fitzpatrick PF.

Biochemistry. 2010 Dec 14;49(49):10440-8. doi: 10.1021/bi1016099. Epub 2010 Nov 16.

PMID:
21067138
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.

Kumar VP, Thomas LM, Bobyk KD, Andi B, Cook PF, West AH.

Biochemistry. 2012 Jan 31;51(4):857-66. doi: 10.1021/bi201808. Epub 2012 Jan 23.

PMID:
22243403
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

pH dependence of a mammalian polyamine oxidase: insights into substrate specificity and the role of lysine 315.

Henderson Pozzi M, Gawandi V, Fitzpatrick PF.

Biochemistry. 2009 Feb 24;48(7):1508-16. doi: 10.1021/bi802227m.

PMID:
19199575
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mechanistic studies of the role of a conserved histidine in a mammalian polyamine oxidase.

Tormos JR, Henderson Pozzi M, Fitzpatrick PF.

Arch Biochem Biophys. 2012 Dec 1;528(1):45-9. doi: 10.1016/j.abb.2012.08.007. Epub 2012 Aug 30.

PMID:
22959971
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Yeast Fms1 is a FAD-utilizing polyamine oxidase.

Landry J, Sternglanz R.

Biochem Biophys Res Commun. 2003 Apr 11;303(3):771-6.

PMID:
12670477
[PubMed - indexed for MEDLINE]
8.

Crystal structures of Fms1 and its complex with spermine reveal substrate specificity.

Huang Q, Liu Q, Hao Q.

J Mol Biol. 2005 May 13;348(4):951-9.

PMID:
15843025
[PubMed - indexed for MEDLINE]
9.

On the catalytic role of the conserved active site residue His466 of choline oxidase.

Ghanem M, Gadda G.

Biochemistry. 2005 Jan 25;44(3):893-904.

PMID:
15654745
[PubMed - indexed for MEDLINE]
10.

Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate.

Royo M, Fitzpatrick PF.

Biochemistry. 2005 May 10;44(18):7079-84.

PMID:
15865452
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Probing mammalian spermine oxidase enzyme-substrate complex through molecular modeling, site-directed mutagenesis and biochemical characterization.

Tavladoraki P, Cervelli M, Antonangeli F, Minervini G, Stano P, Federico R, Mariottini P, Polticelli F.

Amino Acids. 2011 Apr;40(4):1115-26. doi: 10.1007/s00726-010-0735-8. Epub 2010 Sep 14.

PMID:
20839014
[PubMed - indexed for MEDLINE]
12.

Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the pKa values of active site residues and on the pH dependence of catalysis.

Czerwinski RM, Harris TK, Johnson WH Jr, Legler PM, Stivers JT, Mildvan AS, Whitman CP.

Biochemistry. 1999 Sep 21;38(38):12358-66.

PMID:
10493803
[PubMed - indexed for MEDLINE]
13.

Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.

Lin Y, West AH, Cook PF.

Biochemistry. 2009 Aug 4;48(30):7305-12. doi: 10.1021/bi900175z.

PMID:
19530703
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mechanistic studies of human spermine oxidase: kinetic mechanism and pH effects.

Adachi MS, Juarez PR, Fitzpatrick PF.

Biochemistry. 2010 Jan 19;49(2):386-92. doi: 10.1021/bi9017945.

PMID:
20000632
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: spermine is converted to spermidine in vivo by the FMS1-amine oxidase.

Chattopadhyay MK, Tabor CW, Tabor H.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13869-74. Epub 2003 Nov 14.

PMID:
14617780
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase.

Harris TK, Wu G, Massiah MA, Mildvan AS.

Biochemistry. 2000 Feb 22;39(7):1655-74.

PMID:
10677214
[PubMed - indexed for MEDLINE]
17.

Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.

Liu M, Sergienko EA, Guo F, Wang J, Tittmann K, Hübner G, Furey W, Jordan F.

Biochemistry. 2001 Jun 26;40(25):7355-68.

PMID:
11412090
[PubMed - indexed for MEDLINE]
18.

Role of asparagine 510 in the relative timing of substrate bond cleavages in the reaction catalyzed by choline oxidase.

Rungsrisuriyachai K, Gadda G.

Biochemistry. 2010 Mar 23;49(11):2483-90. doi: 10.1021/bi901796a.

PMID:
20163155
[PubMed - indexed for MEDLINE]
19.

A lysine conserved in the monoamine oxidase family is involved in oxidation of the reduced flavin in mouse polyamine oxidase.

Henderson Pozzi M, Fitzpatrick PF.

Arch Biochem Biophys. 2010 Jun 15;498(2):83-8. doi: 10.1016/j.abb.2010.04.015. Epub 2010 Apr 22.

PMID:
20417173
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase.

Quaye O, Cowins S, Gadda G.

J Biol Chem. 2009 Jun 19;284(25):16990-7. doi: 10.1074/jbc.M109.003715. Epub 2009 Apr 27.

PMID:
19398559
[PubMed - indexed for MEDLINE]
Free PMC Article

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