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Results: 1 to 20 of 92

1.

Early cardiovascular changes occurring in diet-induced, obese insulin-resistant rats.

Huisamen B, Dietrich D, Bezuidenhout N, Lopes J, Flepisi B, Blackhurst D, Lochner A.

Mol Cell Biochem. 2012 Sep;368(1-2):37-45. doi: 10.1007/s11010-012-1340-9. Epub 2012 May 26.

PMID:
22638648
[PubMed - indexed for MEDLINE]
2.

The consequences of long-term glycogen synthase kinase-3 inhibition on normal and insulin resistant rat hearts.

Flepisi TB, Lochner A, Huisamen B.

Cardiovasc Drugs Ther. 2013 Oct;27(5):381-92. doi: 10.1007/s10557-013-6467-8.

PMID:
23820981
[PubMed - indexed for MEDLINE]
3.

Myocardial structure, function and ischaemic tolerance in a rodent model of obesity with insulin resistance.

Wensley I, Salaveria K, Bulmer AC, Donner DG, du Toit EF.

Exp Physiol. 2013 Nov;98(11):1552-64. doi: 10.1113/expphysiol.2013.074948. Epub 2013 Jul 12.

PMID:
23851919
[PubMed - indexed for MEDLINE]
4.

ANG II type I receptor antagonism improved nitric oxide production and enhanced eNOS and PKB/Akt expression in hearts from a rat model of insulin resistance.

Huisamen B, Pêrel SJ, Friedrich SO, Salie R, Strijdom H, Lochner A.

Mol Cell Biochem. 2011 Mar;349(1-2):21-31. doi: 10.1007/s11010-010-0656-6. Epub 2010 Dec 11.

PMID:
21153603
[PubMed - indexed for MEDLINE]
5.

Myocardial susceptibility to ischemic-reperfusion injury in a prediabetic model of dietary-induced obesity.

du Toit EF, Smith W, Muller C, Strijdom H, Stouthammer B, Woodiwiss AJ, Norton GR, Lochner A.

Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2336-43. doi: 10.1152/ajpheart.00481.2007. Epub 2008 Mar 21.

PMID:
18359896
[PubMed - indexed for MEDLINE]
Free Article
6.

Effect of chronic CPT-1 inhibition on myocardial ischemia-reperfusion injury (I/R) in a model of diet-induced obesity.

Maarman G, Marais E, Lochner A, du Toit EF.

Cardiovasc Drugs Ther. 2012 Jun;26(3):205-16. doi: 10.1007/s10557-012-6377-1.

PMID:
22407171
[PubMed - indexed for MEDLINE]
7.

High-fat diet obesity associated with insulin resistance increases cell proliferation, estrogen receptor, and PI3K proteins in rat ventral prostate.

Ribeiro DL, Pinto ME, Rafacho A, Bosqueiro JR, Maeda SY, Anselmo-Franci JA, Taboga SR, Góes RM.

J Androl. 2012 Sep-Oct;33(5):854-65. Epub 2012 Mar 22.

PMID:
22441765
[PubMed - indexed for MEDLINE]
Free Article
8.

Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRbeta/IRS-1 and Akt.

Carvalho-Filho MA, Ropelle ER, Pauli RJ, Cintra DE, Tsukumo DM, Silveira LR, Curi R, Carvalheira JB, Velloso LA, Saad MJ.

Diabetologia. 2009 Nov;52(11):2425-34. doi: 10.1007/s00125-009-1498-1.

PMID:
19730809
[PubMed - indexed for MEDLINE]
9.

Activation of Akt kinase accompanies increased cardiac resistance to ischemia/reperfusion in rats after short-term feeding with lard-based high-fat diet and increased sucrose intake.

Ivanova M, Janega P, Matejikova J, Simoncikova P, Pancza D, Ravingerova T, Barancik M.

Nutr Res. 2011 Aug;31(8):631-43. doi: 10.1016/j.nutres.2011.08.005.

PMID:
21925349
[PubMed - indexed for MEDLINE]
10.

High dietary sucrose triggers hyperinsulinemia, increases myocardial beta-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery.

Gonsolin D, Couturier K, Garait B, Rondel S, Novel-Chaté V, Peltier S, Faure P, Gachon P, Boirie Y, Keriel C, Favier R, Pepe S, Demaison L, Leverve X.

Mol Cell Biochem. 2007 Jan;295(1-2):217-28. Epub 2006 Aug 31.

PMID:
16944307
[PubMed - indexed for MEDLINE]
11.

Cardioprotective and anti-hypertensive effects of Prosopis glandulosa in rat models of pre-diabetes.

Huisamen B, George C, Dietrich D, Genade S.

Cardiovasc J Afr. 2013 Mar;24(2):10-6. doi: 10.5830/CVJA-2012-069.

PMID:
23612947
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pre-treatment with a DPP-4 inhibitor is infarct sparing in hearts from obese, pre-diabetic rats.

Huisamen B, Genis A, Marais E, Lochner A.

Cardiovasc Drugs Ther. 2011 Feb;25(1):13-20. doi: 10.1007/s10557-010-6271-7.

PMID:
21088878
[PubMed - indexed for MEDLINE]
13.

Pioglitazone can ameliorate insulin resistance in low-dose streptozotocin and high sucrose-fat diet induced obese rats.

Ding SY, Shen ZF, Chen YT, Sun SJ, Liu Q, Xie MZ.

Acta Pharmacol Sin. 2005 May;26(5):575-80.

PMID:
15842776
[PubMed - indexed for MEDLINE]
Free Article
14.

Chronic melatonin consumption prevents obesity-related metabolic abnormalities and protects the heart against myocardial ischemia and reperfusion injury in a prediabetic model of diet-induced obesity.

Nduhirabandi F, Du Toit EF, Blackhurst D, Marais D, Lochner A.

J Pineal Res. 2011 Mar;50(2):171-82. doi: 10.1111/j.1600-079X.2010.00826.x. Epub 2010 Nov 15.

PMID:
21073520
[PubMed - indexed for MEDLINE]
15.

Sex-dependent differences in rat hepatic lipid accumulation and insulin sensitivity in response to diet-induced obesity.

Nadal-Casellas A, Proenza AM, Lladó I, Gianotti M.

Biochem Cell Biol. 2012 Apr;90(2):164-72. doi: 10.1139/o11-069. Epub 2012 Jan 11.

PMID:
22235846
[PubMed - indexed for MEDLINE]
16.

Impaired contractile function and mitochondrial respiratory capacity in response to oxygen deprivation in a rat model of pre-diabetes.

Essop MF, Anna Chan WY, Valle A, García-Palmer FJ, Du Toit EF.

Acta Physiol (Oxf). 2009 Dec;197(4):289-96. doi: 10.1111/j.1748-1716.2009.02024.x. Epub 2009 Jul 23.

PMID:
19645752
[PubMed - indexed for MEDLINE]
17.

Obesity induces upregulation of genes involved in myocardial Ca2+ handling.

Lima-Leopoldo AP, Sugizaki MM, Leopoldo AS, Carvalho RF, Nogueira CR, Nascimento AF, Martinez PF, Luvizotto RA, Padovani CR, Cicogna AC.

Braz J Med Biol Res. 2008 Jul;41(7):615-20.

PMID:
18719744
[PubMed - indexed for MEDLINE]
Free Article
18.

Effect of insulin and glucose infusion on myocardial infarction size in uraemic rats.

Dikow R, Wasserhess C, Zimmerer K, Kihm LP, Schaier M, Schwenger V, Hardt S, Tiefenbacher C, Katus H, Zeier M, Gross LM.

Basic Res Cardiol. 2009 Sep;104(5):571-9. doi: 10.1007/s00395-009-0018-2. Epub 2009 Mar 14.

PMID:
19288152
[PubMed - indexed for MEDLINE]
19.

Diabetes mellitus abrogates erythropoietin-induced cardioprotection against ischemic-reperfusion injury by alteration of the RISK/GSK-3β signaling.

Ghaboura N, Tamareille S, Ducluzeau PH, Grimaud L, Loufrani L, Croué A, Tourmen Y, Henrion D, Furber A, Prunier F.

Basic Res Cardiol. 2011 Jan;106(1):147-62. doi: 10.1007/s00395-010-0130-3. Epub 2010 Oct 28.

PMID:
20981553
[PubMed - indexed for MEDLINE]
20.

Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide.

Gonon AT, Widegren U, Bulhak A, Salehzadeh F, Persson J, Sjöquist PO, Pernow J.

Cardiovasc Res. 2008 Apr 1;78(1):116-22. doi: 10.1093/cvr/cvn017. Epub 2008 Jan 25.

PMID:
18222959
[PubMed - indexed for MEDLINE]
Free Article

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