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Items: 1 to 20 of 110


Recruitment and retention dynamics of RECQL5 at DNA double strand break sites.

Popuri V, Ramamoorthy M, Tadokoro T, Singh DK, Karmakar P, Croteau DL, Bohr VA.

DNA Repair (Amst). 2012 Jul 1;11(7):624-35. doi: 10.1016/j.dnarep.2012.05.001. Epub 2012 May 24.


The involvement of human RECQL4 in DNA double-strand break repair.

Singh DK, Karmakar P, Aamann M, Schurman SH, May A, Croteau DL, Burks L, Plon SE, Bohr VA.

Aging Cell. 2010 Jun;9(3):358-71. doi: 10.1111/j.1474-9726.2010.00562.x. Epub 2010 Mar 6.


RECQL5 plays co-operative and complementary roles with WRN syndrome helicase.

Popuri V, Huang J, Ramamoorthy M, Tadokoro T, Croteau DL, Bohr VA.

Nucleic Acids Res. 2013 Jan;41(2):881-99. doi: 10.1093/nar/gks1134. Epub 2012 Nov 23.


WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts.

Zecevic A, Menard H, Gurel V, Hagan E, DeCaro R, Zhitkovich A.

Cell Cycle. 2009 Sep 1;8(17):2769-78. Epub 2009 Sep 2.


The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair.

Ramamoorthy M, May A, Tadokoro T, Popuri V, Seidman MM, Croteau DL, Bohr VA.

Carcinogenesis. 2013 Oct;34(10):2218-30. doi: 10.1093/carcin/bgt183. Epub 2013 May 28.


Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks.

Liberti SE, Andersen SD, Wang J, May A, Miron S, Perderiset M, Keijzers G, Nielsen FC, Charbonnier JB, Bohr VA, Rasmussen LJ.

DNA Repair (Amst). 2011 Jan 2;10(1):73-86. doi: 10.1016/j.dnarep.2010.09.023. Epub 2010 Oct 20.


Promyelocytic leukemia protein interacts with werner syndrome helicase and regulates double-strand break repair in γ-irradiation-induced DNA damage responses.

Liu J, Song Y, Qian J, Liu B, Dong Y, Tian B, Sun Z.

Biochemistry (Mosc). 2011 May;76(5):550-4. doi: 10.1134/S000629791105004X.


Human RECQL5: guarding the crossroads of DNA replication and transcription and providing backup capability.

Popuri V, Tadokoro T, Croteau DL, Bohr VA.

Crit Rev Biochem Mol Biol. 2013 May-Jun;48(3):289-99. doi: 10.3109/10409238.2013.792770. Epub 2013 Apr 29. Review.


DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.

Sturzenegger A, Burdova K, Kanagaraj R, Levikova M, Pinto C, Cejka P, Janscak P.

J Biol Chem. 2014 Sep 26;289(39):27314-26. doi: 10.1074/jbc.M114.578823. Epub 2014 Aug 13.


Human RECQL5 participates in the removal of endogenous DNA damage.

Tadokoro T, Ramamoorthy M, Popuri V, May A, Tian J, Sykora P, Rybanska I, Wilson DM 3rd, Croteau DL, Bohr VA.

Mol Biol Cell. 2012 Nov;23(21):4273-85. doi: 10.1091/mbc.E12-02-0110. Epub 2012 Sep 12.


MRE11 complex links RECQ5 helicase to sites of DNA damage.

Zheng L, Kanagaraj R, Mihaljevic B, Schwendener S, Sartori AA, Gerrits B, Shevelev I, Janscak P.

Nucleic Acids Res. 2009 May;37(8):2645-57. doi: 10.1093/nar/gkp147. Epub 2009 Mar 6.


BLM is an early responder to DNA double-strand breaks.

Karmakar P, Seki M, Kanamori M, Hashiguchi K, Ohtsuki M, Murata E, Inoue E, Tada S, Lan L, Yasui A, Enomoto T.

Biochem Biophys Res Commun. 2006 Sep 15;348(1):62-9. Epub 2006 Jul 17.


Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks.

Kusumoto-Matsuo R, Ghosh D, Karmakar P, May A, Ramsden D, Bohr VA.

Aging (Albany NY). 2014 Jan;6(1):70-81.


RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.

Kim TM, Son MY, Dodds S, Hu L, Luo G, Hasty P.

Nucleic Acids Res. 2015 Jan;43(2):893-903. doi: 10.1093/nar/gku1334. Epub 2014 Dec 17.


Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.

Kusumoto R, Dawut L, Marchetti C, Wan Lee J, Vindigni A, Ramsden D, Bohr VA.

Biochemistry. 2008 Jul 15;47(28):7548-56. doi: 10.1021/bi702325t. Epub 2008 Jun 18.


Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions.

Tomimatsu N, Mukherjee B, Deland K, Kurimasa A, Bolderson E, Khanna KK, Burma S.

DNA Repair (Amst). 2012 Apr 1;11(4):441-8. doi: 10.1016/j.dnarep.2012.01.006. Epub 2012 Feb 11.


Direct inhibition of RNA polymerase II transcription by RECQL5.

Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, Svejstrup JQ.

J Biol Chem. 2009 Aug 28;284(35):23197-203. doi: 10.1074/jbc.M109.015750. Epub 2009 Jul 1.


DNA helicases Sgs1 and BLM promote DNA double-strand break resection.

Gravel S, Chapman JR, Magill C, Jackson SP.

Genes Dev. 2008 Oct 15;22(20):2767-72. doi: 10.1101/gad.503108.


Recruitment of HRDC domain of WRN and BLM to the sites of DNA damage induced by mitomycin C and methyl methanesulfonate.

Samanta S, Karmakar P.

Cell Biol Int. 2012 Oct 1;36(10):873-81. doi: 10.1042/CBI20110510.


A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining.

Grabarz A, Guirouilh-Barbat J, Barascu A, Pennarun G, Genet D, Rass E, Germann SM, Bertrand P, Hickson ID, Lopez BS.

Cell Rep. 2013 Oct 17;5(1):21-8. doi: 10.1016/j.celrep.2013.08.034. Epub 2013 Oct 3.

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