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Results: 1 to 20 of 146

1.

Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain.

Bashtrykov P, Jankevicius G, Smarandache A, Jurkowska RZ, Ragozin S, Jeltsch A.

Chem Biol. 2012 May 25;19(5):572-8. doi: 10.1016/j.chembiol.2012.03.010.

PMID:
22633409
[PubMed - indexed for MEDLINE]
Free Article
3.

Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase.

Vilkaitis G, Suetake I, Klimasauskas S, Tajima S.

J Biol Chem. 2005 Jan 7;280(1):64-72. Epub 2004 Oct 27.

PMID:
15509558
[PubMed - indexed for MEDLINE]
Free Article
4.

Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.

Song J, Rechkoblit O, Bestor TH, Patel DJ.

Science. 2011 Feb 25;331(6020):1036-40. doi: 10.1126/science.1195380. Epub 2010 Dec 16.

PMID:
21163962
[PubMed - indexed for MEDLINE]
Free Article
5.

CXXC domain of human DNMT1 is essential for enzymatic activity.

Pradhan M, Estève PO, Chin HG, Samaranayke M, Kim GD, Pradhan S.

Biochemistry. 2008 Sep 23;47(38):10000-9. doi: 10.1021/bi8011725. Epub 2008 Aug 29.

PMID:
18754681
[PubMed - indexed for MEDLINE]
6.

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).

Takeshita K, Suetake I, Yamashita E, Suga M, Narita H, Nakagawa A, Tajima S.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9055-9. doi: 10.1073/pnas.1019629108. Epub 2011 Apr 25.

PMID:
21518897
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.

Frauer C, Rottach A, Meilinger D, Bultmann S, Fellinger K, Hasenöder S, Wang M, Qin W, Söding J, Spada F, Leonhardt H.

PLoS One. 2011 Feb 2;6(2):e16627. doi: 10.1371/journal.pone.0016627.

PMID:
21311766
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites.

Gowher H, Jeltsch A.

J Mol Biol. 2001 Jun 22;309(5):1201-8. Erratum in: J Mol Biol 2001 Jul 20;310(4):951.

PMID:
11399089
[PubMed - indexed for MEDLINE]
9.

Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.

Song J, Teplova M, Ishibe-Murakami S, Patel DJ.

Science. 2012 Feb 10;335(6069):709-12. doi: 10.1126/science.1214453.

PMID:
22323818
[PubMed - indexed for MEDLINE]
Free Article
10.

The DNMT1 target recognition domain resides in the N terminus.

Araujo FD, Croteau S, Slack AD, Milutinovic S, Bigey P, Price GB, Zannis-Hadjopoulos M, Szyf M.

J Biol Chem. 2001 Mar 9;276(10):6930-6. Epub 2000 Dec 4. Erratum in: J Biol Chem. 2007 May 4;282(18):13928. Zannis-Hajopoulos, M [corrected to Zannis-Hadjopoulos, M].

PMID:
11104769
[PubMed - indexed for MEDLINE]
Free Article
11.

The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites.

Hermann A, Goyal R, Jeltsch A.

J Biol Chem. 2004 Nov 12;279(46):48350-9. Epub 2004 Aug 31.

PMID:
15339928
[PubMed - indexed for MEDLINE]
Free Article
12.

The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.

Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A.

J Biol Chem. 2014 Feb 14;289(7):4106-15. doi: 10.1074/jbc.M113.528893. Epub 2013 Dec 24.

PMID:
24368767
[PubMed - indexed for MEDLINE]
13.

Allosteric activator domain of maintenance human DNA (cytosine-5) methyltransferase and its role in methylation spreading.

Pradhan S, Estève PO.

Biochemistry. 2003 May 13;42(18):5321-32.

PMID:
12731873
[PubMed - indexed for MEDLINE]
14.

Hybrid mouse-prokaryotic DNA (cytosine-5) methyltransferases retain the specificity of the parental C-terminal domain.

Pradhan S, Roberts RJ.

EMBO J. 2000 May 2;19(9):2103-14.

PMID:
10790376
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia.

Risner LE, Kuntimaddi A, Lokken AA, Achille NJ, Birch NW, Schoenfelt K, Bushweller JH, Zeleznik-Le NJ.

J Biol Chem. 2013 Oct 11;288(41):29901-10. doi: 10.1074/jbc.M113.474858. Epub 2013 Aug 29.

PMID:
23990460
[PubMed - indexed for MEDLINE]
16.

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase.

Goyal R, Reinhardt R, Jeltsch A.

Nucleic Acids Res. 2006 Feb 25;34(4):1182-8. Print 2006.

PMID:
16500889
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

Valinluck V, Sowers LC.

Cancer Res. 2007 Feb 1;67(3):946-50.

PMID:
17283125
[PubMed - indexed for MEDLINE]
Free Article
18.

Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1.

Kimura H, Shiota K.

J Biol Chem. 2003 Feb 14;278(7):4806-12. Epub 2002 Dec 6.

PMID:
12473678
[PubMed - indexed for MEDLINE]
Free Article
19.

The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1.

Hsieh CL.

BMC Biochem. 2005 Mar 30;6:6.

PMID:
15799776
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The amino-terminus of mouse DNA methyltransferase 1 forms an independent domain and binds to DNA with the sequence involving PCNA binding motif.

Suetake I, Hayata D, Tajima S.

J Biochem. 2006 Dec;140(6):763-76. Epub 2006 Oct 17.

PMID:
17046852
[PubMed - indexed for MEDLINE]

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