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Results: 1 to 20 of 95

1.

Evolutionary pathways in BRCA1-associated breast tumors.

Martins FC, De S, Almendro V, Gönen M, Park SY, Blum JL, Herlihy W, Ethington G, Schnitt SJ, Tung N, Garber JE, Fetten K, Michor F, Polyak K.

Cancer Discov. 2012 Jun;2(6):503-11. doi: 10.1158/2159-8290.CD-11-0325. Epub 2012 Apr 10.

PMID:
22628410
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tracking evolution of BRCA1-associated breast cancer.

Jonkers J.

Cancer Discov. 2012 Jun;2(6):486-8. doi: 10.1158/2159-8290.CD-12-0186.

PMID:
22684454
[PubMed - indexed for MEDLINE]
3.

CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer.

Stefansson OA, Jonasson JG, Olafsdottir K, Hilmarsdottir H, Olafsdottir G, Esteller M, Johannsson OT, Eyfjord JE.

Epigenetics. 2011 May;6(5):638-49. doi: 10.4161/epi.6.5.15667.

PMID:
21593597
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.

Holstege H, Horlings HM, Velds A, Langerød A, Børresen-Dale AL, van de Vijver MJ, Nederlof PM, Jonkers J.

BMC Cancer. 2010 Nov 30;10:654. doi: 10.1186/1471-2407-10-654.

PMID:
21118481
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Beyond BRCA1 and BRCA2 wild-type breast and/or ovarian cancer families: germline mutations in TP53 and PTEN.

Blanco A, Graña B, Fachal L, Santamariña M, Cameselle-Teijeiro J, Ruíz-Ponte C, Carracedo A, Vega A.

Clin Genet. 2010 Feb;77(2):193-6. doi: 10.1111/j.1399-0004.2009.01309.x. Epub 2009 Nov 23. No abstract available.

PMID:
19930417
[PubMed - indexed for MEDLINE]
6.

Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer.

Okumura N, Yoshida H, Kitagishi Y, Nishimura Y, Matsuda S.

Biochem Biophys Res Commun. 2011 Sep 30;413(3):395-9. doi: 10.1016/j.bbrc.2011.08.098. Epub 2011 Aug 27. Review.

PMID:
21893034
[PubMed - indexed for MEDLINE]
7.

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

Holstege H, Joosse SA, van Oostrom CT, Nederlof PM, de Vries A, Jonkers J.

Cancer Res. 2009 Apr 15;69(8):3625-33. doi: 10.1158/0008-5472.CAN-08-3426. Epub 2009 Mar 31.

PMID:
19336573
[PubMed - indexed for MEDLINE]
Free Article
8.

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

Liu X, Holstege H, van der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, van Vliet MH, Wessels LF, Peterse JL, Berns A, Jonkers J.

Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12111-6. Epub 2007 Jul 11.

PMID:
17626182
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells.

Pires MM, Hopkins BD, Saal LH, Parsons RE.

Cancer Biol Ther. 2013 Mar;14(3):246-53. doi: 10.4161/cbt.23297. Epub 2013 Jan 4.

PMID:
23291982
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

High-risk human papilloma virus infection, tumor pathophenotypes, and BRCA1/2 and TP53 status in juvenile breast cancer.

Aceto GM, Solano AR, Neuman MI, Veschi S, Morgano A, Malatesta S, Chacon RD, Pupareli C, Lombardi M, Battista P, Marchetti A, Mariani-Costantini R, Podestà EJ.

Breast Cancer Res Treat. 2010 Aug;122(3):671-83. doi: 10.1007/s10549-009-0596-6. Epub 2009 Oct 23.

PMID:
19851859
[PubMed - indexed for MEDLINE]
11.

Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations.

Phillips KA, Nichol K, Ozcelik H, Knight J, Done SJ, Goodwin PJ, Andrulis IL.

J Natl Cancer Inst. 1999 Mar 3;91(5):469-73.

PMID:
10070948
[PubMed - indexed for MEDLINE]
Free Article
12.

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities.

Press JZ, De Luca A, Boyd N, Young S, Troussard A, Ridge Y, Kaurah P, Kalloger SE, Blood KA, Smith M, Spellman PT, Wang Y, Miller DM, Horsman D, Faham M, Gilks CB, Gray J, Huntsman DG.

BMC Cancer. 2008 Jan 22;8:17. doi: 10.1186/1471-2407-8-17.

PMID:
18208621
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients.

Lee DS, Yoon SY, Looi LM, Kang P, Kang IN, Sivanandan K, Ariffin H, Thong MK, Chin KF, Mohd Taib NA, Yip CH, Teo SH.

Breast Cancer Res. 2012 Apr 16;14(2):R66.

PMID:
22507745
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Growth and molecular interactions of the anti-EGFR antibody cetuximab and the DNA cross-linking agent cisplatin in gefitinib-resistant MDA-MB-468 cells: new prospects in the treatment of triple-negative/basal-like breast cancer.

Oliveras-Ferraros C, Vazquez-Martin A, López-Bonet E, Martín-Castillo B, Del Barco S, Brunet J, Menendez JA.

Int J Oncol. 2008 Dec;33(6):1165-76.

PMID:
19020749
[PubMed - indexed for MEDLINE]
15.

The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.

Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Gruvberger-Saal SK, Saal LH, Holm K, Hegardt C, Arason A, Fagerholm R, Persson C, Grabau D, Johnsson E, Lövgren K, Magnusson L, Heikkilä P, Agnarsson BA, Johannsson OT, Malmström P, Fernö M, Olsson H, Loman N, Nevanlinna H, Barkardottir RB, Borg Å.

Cancer Res. 2012 Aug 15;72(16):4028-36. Epub 2012 Jun 15.

PMID:
22706203
[PubMed - indexed for MEDLINE]
Free Article
16.

p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours.

Crook T, Brooks LA, Crossland S, Osin P, Barker KT, Waller J, Philp E, Smith PD, Yulug I, Peto J, Parker G, Allday MJ, Crompton MR, Gusterson BA.

Oncogene. 1998 Oct 1;17(13):1681-9.

PMID:
9796697
[PubMed - indexed for MEDLINE]
Free Article
17.

Breast cancer predisposition syndromes.

Hemel D, Domchek SM.

Hematol Oncol Clin North Am. 2010 Oct;24(5):799-814. doi: 10.1016/j.hoc.2010.06.004. Review.

PMID:
20816575
[PubMed - indexed for MEDLINE]
18.
19.

Loss of heterozygosity of p53, BRCA1, VHL, and estrogen receptor genes in breast carcinoma: correlation with related protein products and morphologic features.

Otis CN, Krebs PA, Albuquerque A, Quezado MM, San Juan X, Sobel ME, Merino MJ.

Int J Surg Pathol. 2002 Oct;10(4):237-45.

PMID:
12490973
[PubMed - indexed for MEDLINE]
20.

Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer.

Walsh T, Casadei S, Coats KH, Swisher E, Stray SM, Higgins J, Roach KC, Mandell J, Lee MK, Ciernikova S, Foretova L, Soucek P, King MC.

JAMA. 2006 Mar 22;295(12):1379-88.

PMID:
16551709
[PubMed - indexed for MEDLINE]

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