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Items: 1 to 20 of 62

1.

What model organisms and interactomics can reveal about the genetics of human obesity.

Williams MJ, Almén MS, Fredriksson R, Schiöth HB.

Cell Mol Life Sci. 2012 Nov;69(22):3819-34. doi: 10.1007/s00018-012-1022-5. Epub 2012 May 23. Review.

PMID:
22618246
2.

Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.

Ng MC, Tam CH, So WY, Ho JS, Chan AW, Lee HM, Wang Y, Lam VK, Chan JC, Ma RC.

J Clin Endocrinol Metab. 2010 May;95(5):2418-25. doi: 10.1210/jc.2009-2077. Epub 2010 Mar 9.

PMID:
20215397
3.

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.

Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y.

J Hum Genet. 2009 Dec;54(12):727-31. doi: 10.1038/jhg.2009.106. Epub 2009 Oct 23.

PMID:
19851340
4.

Recapitulation of genome-wide association studies on body mass index in the Korean population.

Hong KW, Oh B.

Int J Obes (Lond). 2012 Aug;36(8):1127-30. doi: 10.1038/ijo.2011.202. Epub 2011 Nov 1.

PMID:
22041983
5.

Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.

Dorajoo R, Blakemore AI, Sim X, Ong RT, Ng DP, Seielstad M, Wong TY, Saw SM, Froguel P, Liu J, Tai ES.

Int J Obes (Lond). 2012 Jan;36(1):159-63. doi: 10.1038/ijo.2011.86. Epub 2011 Apr 19.

PMID:
21544081
6.

Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty.

Wang J, Mei H, Chen W, Jiang Y, Sun W, Li F, Fu Q, Jiang F.

Int J Obes (Lond). 2012 Apr;36(4):542-7. doi: 10.1038/ijo.2011.218. Epub 2011 Nov 15.

PMID:
22083549
7.

Expression of fourteen novel obesity-related genes in Zucker diabetic fatty rats.

Schmid PM, Heid I, Buechler C, Steege A, Resch M, Birner C, Endemann DH, Riegger GA, Luchner A.

Cardiovasc Diabetol. 2012 Jul 13;11:48. doi: 10.1186/1475-2840-11-48.

8.

Modelling BMI trajectories in children for genetic association studies.

Warrington NM, Wu YY, Pennell CE, Marsh JA, Beilin LJ, Palmer LJ, Lye SJ, Briollais L.

PLoS One. 2013;8(1):e53897. doi: 10.1371/journal.pone.0053897. Epub 2013 Jan 17.

9.

Functional analysis of seven genes linked to body mass index and adiposity by genome-wide association studies: a review.

Speakman JR.

Hum Hered. 2013;75(2-4):57-79. doi: 10.1159/000353585. Epub 2013 Sep 27. Review. Erratum in: Hum Hered. 2013;76(2):52.

PMID:
24081222
10.

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population.

Hotta K, Kitamoto T, Kitamoto A, Mizusawa S, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Nakao K, Sekine A.

J Hum Genet. 2011 Sep;56(9):647-51. doi: 10.1038/jhg.2011.74. Epub 2011 Jul 28.

PMID:
21796137
11.

Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology.

Bernhard F, Landgraf K, Klöting N, Berthold A, Büttner P, Friebe D, Kiess W, Kovacs P, Blüher M, Körner A.

Diabetologia. 2013 Feb;56(2):311-22. doi: 10.1007/s00125-012-2773-0. Epub 2012 Nov 16.

PMID:
23229156
12.

Expression of new loci associated with obesity in diet-induced obese rats: from genetics to physiology.

Gutierrez-Aguilar R, Kim DH, Woods SC, Seeley RJ.

Obesity (Silver Spring). 2012 Feb;20(2):306-12. doi: 10.1038/oby.2011.236. Epub 2011 Jul 21.

13.

Meta-analysis identifies common variants associated with body mass index in east Asians.

Wen W, Cho YS, Zheng W, Dorajoo R, Kato N, Qi L, Chen CH, Delahanty RJ, Okada Y, Tabara Y, Gu D, Zhu D, Haiman CA, Mo Z, Gao YT, Saw SM, Go MJ, Takeuchi F, Chang LC, Kokubo Y, Liang J, Hao M, Le Marchand L, Zhang Y, Hu Y, Wong TY, Long J, Han BG, Kubo M, Yamamoto K, Su MH, Miki T, Henderson BE, Song H, Tan A, He J, Ng DP, Cai Q, Tsunoda T, Tsai FJ, Iwai N, Chen GK, Shi J, Xu J, Sim X, Xiang YB, Maeda S, Ong RT, Li C, Nakamura Y, Aung T, Kamatani N, Liu JJ, Lu W, Yokota M, Seielstad M, Fann CS; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Wu JY, Lee JY, Hu FB, Tanaka T, Tai ES, Shu XO.

Nat Genet. 2012 Feb 19;44(3):307-11. doi: 10.1038/ng.1087.

14.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstråle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N; Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN; Genetic Investigation of ANthropometric Traits Consortium.

Nat Genet. 2009 Jan;41(1):25-34. doi: 10.1038/ng.287. Epub 2008 Dec 14.

15.

Nutritional state affects the expression of the obesity-associated genes Etv5, Faim2, Fto, and Negr1.

Boender AJ, van Rozen AJ, Adan RA.

Obesity (Silver Spring). 2012 Dec;20(12):2420-5. doi: 10.1038/oby.2012.128. Epub 2012 May 7.

16.

Role of BMI-associated loci identified in GWAS meta-analyses in the context of common childhood obesity in European Americans.

Zhao J, Bradfield JP, Zhang H, Sleiman PM, Kim CE, Glessner JT, Deliard S, Thomas KA, Frackelton EC, Li M, Chiavacci RM, Berkowitz RI, Hakonarson H, Grant SF.

Obesity (Silver Spring). 2011 Dec;19(12):2436-9. doi: 10.1038/oby.2011.237. Epub 2011 Jul 21.

17.

Genetic determinants of obesity and related vascular diseases.

Winter Y, Sankowski R, Back T.

Vitam Horm. 2013;91:29-48. doi: 10.1016/B978-0-12-407766-9.00002-X. Review.

PMID:
23374711
18.

Genetic risk profiles for a childhood with severe overweight.

González JR, Estévez MN, Giralt PS, Cáceres A, Pérez LM, González-Carpio M, Ballester F, Sunyer J, Rodríguez-López R.

Pediatr Obes. 2014 Aug;9(4):272-80. doi: 10.1111/j.2047-6310.2013.00166.x. Epub 2013 Apr 29.

PMID:
23629956
19.

Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.

Haupt A, Thamer C, Heni M, Machicao F, Machann J, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

Obesity (Silver Spring). 2010 Jun;18(6):1212-7. doi: 10.1038/oby.2009.413. Epub 2009 Nov 12.

20.

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K.

Nat Genet. 2009 Jan;41(1):18-24. doi: 10.1038/ng.274. Epub 2008 Dec 14.

PMID:
19079260
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