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Results: 1 to 20 of 95

1.

Nicotinamide nucleotide transhydrogenase (NNT) acts as a novel modulator of macrophage inflammatory responses.

Ripoll VM, Meadows NA, Bangert M, Lee AW, Kadioglu A, Cox RD.

FASEB J. 2012 Aug;26(8):3550-62. doi: 10.1096/fj.11-199935. Epub 2012 May 16.

PMID:
22593545
[PubMed - indexed for MEDLINE]
Free Article
2.

A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities.

Ronchi JA, Figueira TR, Ravagnani FG, Oliveira HC, Vercesi AE, Castilho RF.

Free Radic Biol Med. 2013 Oct;63:446-56. doi: 10.1016/j.freeradbiomed.2013.05.049. Epub 2013 Jun 7.

PMID:
23747984
[PubMed - indexed for MEDLINE]
Free Article
3.

Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

Freeman H, Shimomura K, Cox RD, Ashcroft FM.

Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10.

PMID:
17052203
[PubMed - indexed for MEDLINE]
4.

Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.

Freeman H, Shimomura K, Horner E, Cox RD, Ashcroft FM.

Cell Metab. 2006 Jan;3(1):35-45.

PMID:
16399503
[PubMed - indexed for MEDLINE]
Free Article
5.

The deletion variant of nicotinamide nucleotide transhydrogenase (Nnt) does not affect insulin secretion or glucose tolerance.

Wong N, Blair AR, Morahan G, Andrikopoulos S.

Endocrinology. 2010 Jan;151(1):96-102. doi: 10.1210/en.2009-0887. Epub 2009 Nov 11.

PMID:
19906813
[PubMed - indexed for MEDLINE]
6.

Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice.

Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD.

Diabetes. 2006 Jul;55(7):2153-6. Erratum in: Diabetes. 2014 Feb;63(2):815.

PMID:
16804088
[PubMed - indexed for MEDLINE]
Free Article
7.

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.

Parker N, Vidal-Puig AJ, Azzu V, Brand MD.

Biochim Biophys Acta. 2009 Dec;1787(12):1451-7. doi: 10.1016/j.bbabio.2009.06.005. Epub 2009 Jun 17.

PMID:
19539600
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency.

Meimaridou E, Kowalczyk J, Guasti L, Hughes CR, Wagner F, Frommolt P, Nürnberg P, Mann NP, Banerjee R, Saka HN, Chapple JP, King PJ, Clark AJ, Metherell LA.

Nat Genet. 2012 May 27;44(7):740-2. doi: 10.1038/ng.2299.

PMID:
22634753
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Insulin secretion from beta-cells is affected by deletion of nicotinamide nucleotide transhydrogenase.

Shimomura K, Galvanovskis J, Goldsworthy M, Hugill A, Kaizak S, Lee A, Meadows N, Quwailid MM, Rydström J, Teboul L, Ashcroft F, Cox RD.

Methods Enzymol. 2009;457:451-80. doi: 10.1016/S0076-6879(09)05025-3.

PMID:
19426883
[PubMed - indexed for MEDLINE]
10.

Paraoxonase 1 (PON1) reduces macrophage inflammatory responses.

Aharoni S, Aviram M, Fuhrman B.

Atherosclerosis. 2013 Jun;228(2):353-61. doi: 10.1016/j.atherosclerosis.2013.03.005. Epub 2013 Mar 20.

PMID:
23582715
[PubMed - indexed for MEDLINE]
11.

Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells.

Yin F, Sancheti H, Cadenas E.

Biochim Biophys Acta. 2012 Mar;1817(3):401-9. doi: 10.1016/j.bbabio.2011.12.004. Epub 2011 Dec 16.

PMID:
22198343
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS).

Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, Siegel RM.

J Exp Med. 2011 Mar 14;208(3):519-33. doi: 10.1084/jem.20102049. Epub 2011 Jan 31.

PMID:
21282379
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Induction of soluble antitumoral mediators by synthetic analogues of bacterial lipoprotein in bone marrow-derived macrophages from LPS-responder and -nonresponder mice.

Pfannes SD, Müller B, Körner S, Bessler WG, Hoffmann P.

J Leukoc Biol. 2001 Apr;69(4):590-7.

PMID:
11310845
[PubMed - indexed for MEDLINE]
Free Article
14.

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S.

Nature. 2011 Apr 28;472(7344):476-80. doi: 10.1038/nature09973.

PMID:
21525932
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Uncoupling protein 2 negatively regulates mitochondrial reactive oxygen species generation and induces phosphatase-mediated anti-inflammatory response in experimental visceral leishmaniasis.

Basu Ball W, Kar S, Mukherjee M, Chande AG, Mukhopadhyaya R, Das PK.

J Immunol. 2011 Aug 1;187(3):1322-32. doi: 10.4049/jimmunol.1004237. Epub 2011 Jun 24.

PMID:
21705615
[PubMed - indexed for MEDLINE]
Free Article
16.

Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-kappaB signaling pathways in N9 microglia induced by lipopolysaccharide.

Zhang L, Wu C, Zhao S, Yuan D, Lian G, Wang X, Wang L, Yang J.

Int Immunopharmacol. 2010 Mar;10(3):331-8. doi: 10.1016/j.intimp.2009.12.004. Epub 2009 Dec 16.

PMID:
20018257
[PubMed - indexed for MEDLINE]
17.

Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling.

Hsing CH, Lin MC, Choi PC, Huang WC, Kai JI, Tsai CC, Cheng YL, Hsieh CY, Wang CY, Chang YP, Chen YH, Chen CL, Lin CF.

PLoS One. 2011 Mar 8;6(3):e17598. doi: 10.1371/journal.pone.0017598.

PMID:
21408125
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Redox-sensitive regulation of macrophage-inducible nitric oxide synthase expression in vitro does not correlate with the failure of apocynin to prevent lung inflammation induced by endotoxin.

Viačková D, Pekarová M, Crhák T, Búcsaiová M, Matiašovic J, Lojek A, Kubala L.

Immunobiology. 2011 Apr;216(4):457-65. doi: 10.1016/j.imbio.2010.09.005. Epub 2010 Nov 18.

PMID:
21093096
[PubMed - indexed for MEDLINE]
19.

Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells.

Boots AW, Gerloff K, Bartholomé R, van Berlo D, Ledermann K, Haenen GR, Bast A, van Schooten FJ, Albrecht C, Schins RP.

Biochim Biophys Acta. 2012 Jul;1823(7):1151-62. doi: 10.1016/j.bbamcr.2012.04.012. Epub 2012 May 1.

PMID:
22575681
[PubMed - indexed for MEDLINE]
Free Article
20.

Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene.

Nicholson A, Reifsnyder PC, Malcolm RD, Lucas CA, MacGregor GR, Zhang W, Leiter EH.

Obesity (Silver Spring). 2010 Oct;18(10):1902-5. doi: 10.1038/oby.2009.477. Epub 2010 Jan 7.

PMID:
20057372
[PubMed - indexed for MEDLINE]
Free PMC Article

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