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Results: 1 to 20 of 94

1.

Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis.

Shefner J, Cedarbaum JM, Cudkowicz ME, Maragakis N, Lee J, Jones D, Watson ML, Mahoney K, Chen M, Saikali K, Mao J, Russell AJ, Hansen RL, Malik F, Wolff AA; Neals/Cytokinetics Study Team.

Amyotroph Lateral Scler. 2012 Sep;13(5):430-8. doi: 10.3109/17482968.2012.684214. Epub 2012 May 16.

PMID:
22591195
[PubMed - indexed for MEDLINE]
2.

Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).

Miller RG, Mitchell JD, Lyon M, Moore DH.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2003 Sep;4(3):191-206. Review.

PMID:
13129806
[PubMed - indexed for MEDLINE]
3.

A study to evaluate safety and tolerability of repeated doses of tirasemtiv in patients with amyotrophic lateral sclerosis.

Shefner JM, Watson ML, Meng L, Wolff AA; Neals/Cytokinetics STUDY Team.

Amyotroph Lateral Scler Frontotemporal Degener. 2013 Dec;14(7-8):574-81. doi: 10.3109/21678421.2013.822517. Epub 2013 Aug 19.

PMID:
23952636
[PubMed - indexed for MEDLINE]
4.

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II.

Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V.

Lancet. 1996 May 25;347(9013):1425-31.

PMID:
8676624
[PubMed - indexed for MEDLINE]
5.

High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study.

Graf M, Ecker D, Horowski R, Kramer B, Riederer P, Gerlach M, Hager C, Ludolph AC, Becker G, Osterhage J, Jost WH, Schrank B, Stein C, Kostopulos P, Lubik S, Wekwerth K, Dengler R, Troeger M, Wuerz A, Hoge A, Schrader C, Schimke N, Krampfl K, Petri S, Zierz S, Eger K, Neudecker S, Traufeller K, Sievert M, Neundörfer B, Hecht M; German vitamin E/ALS Study Group.

J Neural Transm. 2005 May;112(5):649-60. Epub 2004 Oct 27.

PMID:
15517433
[PubMed - indexed for MEDLINE]
6.

[Adverse efects of riluzole (Rilutek) in the treatment of amyotrophic lateral sclerosis].

Roch-Torreilles I, Camu W, Hillaire-Buys D.

Therapie. 2000 Mar-Apr;55(2):303-12. French.

PMID:
10967703
[PubMed - indexed for MEDLINE]
7.

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group.

Bensimon G, Lacomblez L, Meininger V.

N Engl J Med. 1994 Mar 3;330(9):585-91.

PMID:
8302340
[PubMed - indexed for MEDLINE]
Free Article
8.

Riluzole and amyotrophic lateral sclerosis survival: a population-based study in southern Italy.

Zoccolella S, Beghi E, Palagano G, Fraddosio A, Guerra V, Samarelli V, Lepore V, Simone IL, Lamberti P, Serlenga L, Logroscino G; SLAP registry.

Eur J Neurol. 2007 Mar;14(3):262-8.

PMID:
17355545
[PubMed - indexed for MEDLINE]
9.

The relationship between tirasemtiv serum concentration and functional outcomes in patients with ALS.

Shefner JM, Wolff AA, Meng L.

Amyotroph Lateral Scler Frontotemporal Degener. 2013 Dec;14(7-8):582-5. doi: 10.3109/21678421.2013.817587. Epub 2013 Aug 19.

PMID:
23952600
[PubMed - indexed for MEDLINE]
10.

A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?

Bellingham MC.

CNS Neurosci Ther. 2011 Feb;17(1):4-31. doi: 10.1111/j.1755-5949.2009.00116.x. Review.

PMID:
20236142
[PubMed - indexed for MEDLINE]
11.

Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis.

Gordon PH, Moore DH, Gelinas DF, Qualls C, Meister ME, Werner J, Mendoza M, Mass J, Kushner G, Miller RG.

Neurology. 2004 May 25;62(10):1845-7.

PMID:
15159491
[PubMed - indexed for MEDLINE]
12.

[Tolerance of riluzole in a phase IIIb clinical trial].

Lacomblez L, Dib M, Doppler V, Faudet A, Robin V, Salachas F, Bensimon G, Meininger V.

Therapie. 2002 Jan-Feb;57(1):65-71. French.

PMID:
12090150
[PubMed - indexed for MEDLINE]
13.

A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis.

Pascuzzi RM, Shefner J, Chappell AS, Bjerke JS, Tamura R, Chaudhry V, Clawson L, Haas L, Rothstein JD.

Amyotroph Lateral Scler. 2010 May 3;11(3):266-71. doi: 10.3109/17482960903307805.

PMID:
19961264
[PubMed - indexed for MEDLINE]
14.

The Rilutek (riluzole) Global Early Access Programme: an open-label safety evaluation in the treatment of amyotrophic lateral sclerosis.

Debove C, Zeisser P, Salzman PM, Powe LK, Truffinet P.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2001 Sep;2(3):153-8.

PMID:
11771772
[PubMed - indexed for MEDLINE]
15.

Plasma glutamate and glycine levels in patients with amyotrophic lateral sclerosis: the effect of riluzole treatment.

Andreadou E, Kapaki E, Kokotis P, Paraskevas GP, Katsaros N, Libitaki G, Zis V, Sfagos C, Vassilopoulos D.

Clin Neurol Neurosurg. 2008 Mar;110(3):222-6. Epub 2007 Dec 4.

PMID:
18055102
[PubMed - indexed for MEDLINE]
16.

A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis.

Bensimon G, Lacomblez L, Delumeau JC, Bejuit R, Truffinet P, Meininger V; Riluzole/ALS Study Group II.

J Neurol. 2002 May;249(5):609-15.

PMID:
12021952
[PubMed - indexed for MEDLINE]
17.

Toward more efficient clinical trials for amyotrophic lateral sclerosis.

Cudkowicz ME, Katz J, Moore DH, O'Neill G, Glass JD, Mitsumoto H, Appel S, Ravina B, Kieburtz K, Shoulson I, Kaufmann P, Khan J, Simpson E, Shefner J, Levin B, Cwik V, Schoenfeld D, Aggarwal S, McDermott MP, Miller RG.

Amyotroph Lateral Scler. 2010 May 3;11(3):259-65. doi: 10.3109/17482960903358865. Review.

PMID:
19961263
[PubMed - indexed for MEDLINE]
18.

Long-term safety of riluzole in amyotrophic lateral sclerosis.

Lacomblez L, Bensimon G, Leigh PN, Debove C, Bejuit R, Truffinet P, Meininger V; ALS Study Groups I and II.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2002 Mar;3(1):23-9.

PMID:
12061945
[PubMed - indexed for MEDLINE]
19.

A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers.

Levine TD, Bowser R, Hank N, Saperstein D.

Amyotroph Lateral Scler. 2010 Dec;11(6):514-9. doi: 10.3109/17482968.2010.513052. Epub 2010 Sep 14.

PMID:
20839903
[PubMed - indexed for MEDLINE]
20.

Riluzole use during pregnancy in a patient with amyotrophic lateral sclerosis: a case report.

Kawamichi Y, Makino Y, Matsuda Y, Miyazaki K, Uchiyama S, Ohta H.

J Int Med Res. 2010 Mar-Apr;38(2):720-6.

PMID:
20515588
[PubMed - indexed for MEDLINE]

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