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Results: 1 to 20 of 108

1.

Modulation of eIF5A expression using SNS01 nanoparticles inhibits NF-κB activity and tumor growth in murine models of multiple myeloma.

Taylor CA, Liu Z, Tang TC, Zheng Q, Francis S, Wang TW, Ye B, Lust JA, Dondero R, Thompson JE.

Mol Ther. 2012 Jul;20(7):1305-14. doi: 10.1038/mt.2012.94. Epub 2012 May 15.

PMID:
22588272
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

SNS01-T Modulation of eIF5A Inhibits B-cell Cancer Progression and Synergizes With Bortezomib and Lenalidomide.

Francis SM, Taylor CA, Tang T, Liu Z, Zheng Q, Dondero R, Thompson JE.

Mol Ther. 2014 Sep;22(9):1643-52. doi: 10.1038/mt.2014.24. Epub 2014 Feb 26.

PMID:
24569836
[PubMed - in process]
3.

The effect of hypusine modification on the intracellular localization of eIF5A.

Lee SB, Park JH, Kaevel J, Sramkova M, Weigert R, Park MH.

Biochem Biophys Res Commun. 2009 Jun 12;383(4):497-502. doi: 10.1016/j.bbrc.2009.04.049. Epub 2009 Apr 18.

PMID:
19379712
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma.

Lee NP, Tsang FH, Shek FH, Mao M, Dai H, Zhang C, Dong S, Guan XY, Poon RT, Luk JM.

Int J Cancer. 2010 Aug 15;127(4):968-76. doi: 10.1002/ijc.25100.

PMID:
19998337
[PubMed - indexed for MEDLINE]
5.

Eukaryotic translation initiation factor 5A induces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor alpha signalling.

Taylor CA, Sun Z, Cliche DO, Ming H, Eshaque B, Jin S, Hopkins MT, Thai B, Thompson JE.

Exp Cell Res. 2007 Feb 1;313(3):437-49. Epub 2006 Oct 28.

PMID:
17187778
[PubMed - indexed for MEDLINE]
6.

A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis.

Li AL, Li HY, Jin BF, Ye QN, Zhou T, Yu XD, Pan X, Man JH, He K, Yu M, Hu MR, Wang J, Yang SC, Shen BF, Zhang XM.

J Biol Chem. 2004 Nov 19;279(47):49251-8. Epub 2004 Sep 14.

PMID:
15371445
[PubMed - indexed for MEDLINE]
Free Article
7.

The role of eIF5A in epidermal growth factor-induced proliferation of corneal epithelial cell association with PI3-k/Akt activation.

Ding L, Gao LJ, Gu PQ, Guo SY, Cai YQ, Zhou XT.

Mol Vis. 2011 Jan 6;17:16-22.

PMID:
21224998
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mutational analyses of human eIF5A-1--identification of amino acid residues critical for eIF5A activity and hypusine modification.

Cano VS, Jeon GA, Johansson HE, Henderson CA, Park JH, Valentini SR, Hershey JW, Park MH.

FEBS J. 2008 Jan;275(1):44-58. Epub 2007 Dec 6.

PMID:
18067580
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation.

Parreiras-e-Silva LT, Luchessi AD, Reis RI, Oliver C, Jamur MC, Ramos RG, Oliveira EB, Curi R, Costa-Neto CM.

J Cell Physiol. 2010 Nov;225(2):500-5. doi: 10.1002/jcp.22229.

PMID:
20458750
[PubMed - indexed for MEDLINE]
10.

Interference with nuclear factor kappa B and c-Jun NH2-terminal kinase signaling by TRAF6C small interfering RNA inhibits myeloma cell proliferation and enhances apoptosis.

Chen H, Li M, Campbell RA, Burkhardt K, Zhu D, Li SG, Lee HJ, Wang C, Zeng Z, Gordon MS, Bonavida B, Berenson JR.

Oncogene. 2006 Oct 19;25(49):6520-7. Epub 2006 May 15.

PMID:
16702955
[PubMed - indexed for MEDLINE]
11.

Blocking eIF5A modification in cervical cancer cells alters the expression of cancer-related genes and suppresses cell proliferation.

Mémin E, Hoque M, Jain MR, Heller DS, Li H, Cracchiolo B, Hanauske-Abel HM, Pe'ery T, Mathews MB.

Cancer Res. 2014 Jan 15;74(2):552-62. doi: 10.1158/0008-5472.CAN-13-0474. Epub 2013 Nov 12.

PMID:
24220243
[PubMed - indexed for MEDLINE]
12.

Dimerization of the yeast eukaryotic translation initiation factor 5A requires hypusine and is RNA dependent.

Gentz PM, Blatch GL, Dorrington RA.

FEBS J. 2009 Feb;276(3):695-706. doi: 10.1111/j.1742-4658.2008.06817.x. Epub 2008 Dec 17.

PMID:
19120453
[PubMed - indexed for MEDLINE]
13.

Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury.

Moore CC, Martin EN, Lee G, Taylor C, Dondero R, Reznikov LL, Dinarello C, Thompson J, Scheld WM.

J Infect Dis. 2008 Nov 1;198(9):1407-14. doi: 10.1086/592222.

PMID:
18793104
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

Maier B, Ogihara T, Trace AP, Tersey SA, Robbins RD, Chakrabarti SK, Nunemaker CS, Stull ND, Taylor CA, Thompson JE, Dondero RS, Lewis EC, Dinarello CA, Nadler JL, Mirmira RG.

J Clin Invest. 2010 Jun;120(6):2156-70. doi: 10.1172/JCI38924. Epub 2010 May 24.

PMID:
20501948
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy.

Patel PH, Costa-Mattioli M, Schulze KL, Bellen HJ.

J Cell Biol. 2009 Jun 29;185(7):1181-94. doi: 10.1083/jcb.200904161. Epub 2009 Jun 22.

PMID:
19546244
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.

Parreiras-E-Silva LT, Gomes MD, Oliveira EB, Costa-Neto CM.

Biochem Biophys Res Commun. 2007 Oct 19;362(2):393-8. Epub 2007 Aug 13.

PMID:
17707773
[PubMed - indexed for MEDLINE]
17.

SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth.

Feng R, Anderson G, Xiao G, Elliott G, Leoni L, Mapara MY, Roodman GD, Lentzsch S.

Blood. 2007 Mar 1;109(5):2130-8. Epub 2006 Nov 9.

PMID:
17095620
[PubMed - indexed for MEDLINE]
Free Article
18.

Translational control of eIF5A in various diseases.

Kaiser A.

Amino Acids. 2012 Feb;42(2-3):679-84. doi: 10.1007/s00726-011-1042-8. Epub 2011 Aug 5. Review.

PMID:
21818564
[PubMed - indexed for MEDLINE]
19.

Acetylation regulates subcellular localization of eukaryotic translation initiation factor 5A (eIF5A).

Ishfaq M, Maeta K, Maeda S, Natsume T, Ito A, Yoshida M.

FEBS Lett. 2012 Sep 21;586(19):3236-41. doi: 10.1016/j.febslet.2012.06.042. Epub 2012 Jul 4. Erratum in: FEBS Lett. 2014 Aug 19;588(16):2754.

PMID:
22771473
[PubMed - indexed for MEDLINE]
Free Article
20.

Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation.

Luchessi AD, Cambiaghi TD, Hirabara SM, Lambertucci RH, Silveira LR, Baptista IL, Moriscot AS, Costa-Neto CM, Curi R.

J Cell Physiol. 2009 Mar;218(3):480-9. doi: 10.1002/jcp.21619.

PMID:
19006180
[PubMed - indexed for MEDLINE]

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