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Results: 1 to 20 of 118

1.

A locally closed conformation of a bacterial pentameric proton-gated ion channel.

Prevost MS, Sauguet L, Nury H, Van Renterghem C, Huon C, Poitevin F, Baaden M, Delarue M, Corringer PJ.

Nat Struct Mol Biol. 2012 May 13;19(6):642-9. doi: 10.1038/nsmb.2307.

PMID:
22580559
[PubMed - indexed for MEDLINE]
2.

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel.

Hilf RJ, Dutzler R.

Nature. 2009 Jan 1;457(7225):115-8. doi: 10.1038/nature07461. Epub 2008 Nov 5.

PMID:
18987630
[PubMed - indexed for MEDLINE]
3.

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation.

Bocquet N, Nury H, Baaden M, Le Poupon C, Changeux JP, Delarue M, Corringer PJ.

Nature. 2009 Jan 1;457(7225):111-4. doi: 10.1038/nature07462. Epub 2008 Nov 5.

PMID:
18987633
[PubMed - indexed for MEDLINE]
4.

Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography.

Gonzalez-Gutierrez G, Cuello LG, Nair SK, Grosman C.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18716-21. doi: 10.1073/pnas.1313156110. Epub 2013 Oct 28.

PMID:
24167270
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.

Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):966-71. doi: 10.1073/pnas.1314997111. Epub 2013 Dec 23.

PMID:
24367074
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities.

Ghosh B, Satyshur KA, Czajkowski C.

J Biol Chem. 2013 Jun 14;288(24):17420-31. doi: 10.1074/jbc.M113.464040. Epub 2013 May 2.

PMID:
23640880
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family.

Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ.

Nature. 2007 Jan 4;445(7123):116-9. Epub 2006 Dec 10.

PMID:
17167423
[PubMed - indexed for MEDLINE]
8.

Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel.

Nury H, Bocquet N, Le Poupon C, Raynal B, Haouz A, Corringer PJ, Delarue M.

J Mol Biol. 2010 Feb 5;395(5):1114-27. doi: 10.1016/j.jmb.2009.11.024. Epub 2009 Nov 13.

PMID:
19917292
[PubMed - indexed for MEDLINE]
9.

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue.

Nury H, Poitevin F, Van Renterghem C, Changeux JP, Corringer PJ, Delarue M, Baaden M.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6275-80. doi: 10.1073/pnas.1001832107. Epub 2010 Mar 22.

PMID:
20308576
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Gating transition of pentameric ligand-gated ion channels.

Zhu F, Hummer G.

Biophys J. 2009 Nov 4;97(9):2456-63. doi: 10.1016/j.bpj.2009.08.020.

PMID:
19883588
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Pore opening and closing of a pentameric ligand-gated ion channel.

Zhu F, Hummer G.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19814-9. doi: 10.1073/pnas.1009313107. Epub 2010 Nov 1.

PMID:
21041674
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility.

Parikh RB, Bali M, Akabas MH.

J Biol Chem. 2011 Apr 22;286(16):14098-109. doi: 10.1074/jbc.M111.221895. Epub 2011 Mar 1.

PMID:
21362624
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions.

Dellisanti CD, Ghosh B, Hanson SM, Raspanti JM, Grant VA, Diarra GM, Schuh AM, Satyshur K, Klug CS, Czajkowski C.

PLoS Biol. 2013 Nov;11(11):e1001714. doi: 10.1371/journal.pbio.1001714. Epub 2013 Nov 19.

PMID:
24260024
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues.

Corringer PJ, Baaden M, Bocquet N, Delarue M, Dufresne V, Nury H, Prevost M, Van Renterghem C.

J Physiol. 2010 Feb 15;588(Pt 4):565-72. doi: 10.1113/jphysiol.2009.183160. Epub 2009 Dec 7. Review.

PMID:
19995852
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus.

Khurana E, Dal Peraro M, DeVane R, Vemparala S, DeGrado WF, Klein ML.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1069-74. doi: 10.1073/pnas.0811720106. Epub 2009 Jan 14.

PMID:
19144924
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Intramembrane proton binding site linked to activation of bacterial pentameric ion channel.

Wang HL, Cheng X, Sine SM.

J Biol Chem. 2012 Feb 24;287(9):6482-9. doi: 10.1074/jbc.M111.305839. Epub 2011 Nov 14.

PMID:
22084238
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).

Velisetty P, Chalamalasetti SV, Chakrapani S.

J Biol Chem. 2014 Jan 31;289(5):3013-25. doi: 10.1074/jbc.M113.523050. Epub 2013 Dec 13.

PMID:
24338475
[PubMed - indexed for MEDLINE]
18.

Unravelling the conformational plasticity of the extracellular domain of a prokaryotic nAChR homologue in solution by NMR.

Chasapis CT, Argyriou AI, Corringer PJ, Bentrop D, Spyroulias GA.

Biochemistry. 2011 Nov 15;50(45):9681-3. doi: 10.1021/bi201223u. Epub 2011 Oct 20.

PMID:
22007668
[PubMed - indexed for MEDLINE]
19.

Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC).

Velisetty P, Chalamalasetti SV, Chakrapani S.

J Biol Chem. 2012 Oct 26;287(44):36864-72. doi: 10.1074/jbc.M112.401067. Epub 2012 Sep 13.

PMID:
22977232
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.

Nury H, Van Renterghem C, Weng Y, Tran A, Baaden M, Dufresne V, Changeux JP, Sonner JM, Delarue M, Corringer PJ.

Nature. 2011 Jan 20;469(7330):428-31. doi: 10.1038/nature09647.

PMID:
21248852
[PubMed - indexed for MEDLINE]

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