Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 117


Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication.

Duxin JP, Moore HR, Sidorova J, Karanja K, Honaker Y, Dao B, Piwnica-Worms H, Campbell JL, Monnat RJ Jr, Stewart SA.

J Biol Chem. 2012 Jun 22;287(26):21980-91. doi: 10.1074/jbc.M112.359018. Epub 2012 May 7.


Human Dna2 is a nuclear and mitochondrial DNA maintenance protein.

Duxin JP, Dao B, Martinsson P, Rajala N, Guittat L, Campbell JL, Spelbrink JN, Stewart SA.

Mol Cell Biol. 2009 Aug;29(15):4274-82. doi: 10.1128/MCB.01834-08. Epub 2009 Jun 1.


Biochemical analysis of human Dna2.

Masuda-Sasa T, Imamura O, Campbell JL.

Nucleic Acids Res. 2006 Apr 4;34(6):1865-75. Print 2006.


The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication.

Levikova M, Cejka P.

Nucleic Acids Res. 2015 Sep 18;43(16):7888-97. doi: 10.1093/nar/gkv710. Epub 2015 Jul 14.


Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates.

Zheng L, Zhou M, Guo Z, Lu H, Qian L, Dai H, Qiu J, Yakubovskaya E, Bogenhagen DF, Demple B, Shen B.

Mol Cell. 2008 Nov 7;32(3):325-36. doi: 10.1016/j.molcel.2008.09.024.


Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.

Kang HY, Choi E, Bae SH, Lee KH, Gim BS, Kim HD, Park C, MacNeill SA, Seo YS.

Genetics. 2000 Jul;155(3):1055-67.


Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae.

Stewart JA, Campbell JL, Bambara RA.

J Biol Chem. 2009 Mar 27;284(13):8283-91. doi: 10.1074/jbc.M809189200. Epub 2009 Jan 29.


Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.

Kang YH, Lee CH, Seo YS.

Crit Rev Biochem Mol Biol. 2010 Apr;45(2):71-96. doi: 10.3109/10409230903578593. Review.


Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

Ayyagari R, Gomes XV, Gordenin DA, Burgers PM.

J Biol Chem. 2003 Jan 17;278(3):1618-25. Epub 2002 Nov 6.


Isolation of human Dna2 endonuclease and characterization of its enzymatic properties.

Kim JH, Kim HD, Ryu GH, Kim DH, Hurwitz J, Seo YS.

Nucleic Acids Res. 2006 Apr 4;34(6):1854-64. Print 2006.


The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants.

Imamura O, Campbell JL.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8193-8. Epub 2003 Jun 25.


Caenorhabditis elegans DNA-2 helicase/endonuclease plays a vital role in maintaining genome stability, morphogenesis, and life span.

Lee MH, Hollis SE, Yoo BH, Nykamp K.

Biochem Biophys Res Commun. 2011 Apr 15;407(3):495-500. doi: 10.1016/j.bbrc.2011.03.045. Epub 2011 Mar 23.


Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway.

Pike JE, Burgers PM, Campbell JL, Bambara RA.

J Biol Chem. 2009 Sep 11;284(37):25170-80. doi: 10.1074/jbc.M109.023325. Epub 2009 Jul 15.


In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication.

Sharma S, Sommers JA, Brosh RM Jr.

Hum Mol Genet. 2004 Oct 1;13(19):2247-61. Epub 2004 Jul 28.


Processing of G4 DNA by Dna2 helicase/nuclease and replication protein A (RPA) provides insights into the mechanism of Dna2/RPA substrate recognition.

Masuda-Sasa T, Polaczek P, Peng XP, Chen L, Campbell JL.

J Biol Chem. 2008 Sep 5;283(36):24359-73. doi: 10.1074/jbc.M802244200. Epub 2008 Jun 30.


FEN1 ensures telomere stability by facilitating replication fork re-initiation.

Saharia A, Teasley DC, Duxin JP, Dao B, Chiappinelli KB, Stewart SA.

J Biol Chem. 2010 Aug 27;285(35):27057-66. doi: 10.1074/jbc.M110.112276. Epub 2010 Jun 15.


Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates.

Balakrishnan L, Stewart J, Polaczek P, Campbell JL, Bambara RA.

J Biol Chem. 2010 Feb 12;285(7):4398-404. doi: 10.1074/jbc.M109.086397. Epub 2009 Dec 17.


Flap endonuclease disengages Dna2 helicase/nuclease from Okazaki fragment flaps.

Stewart JA, Campbell JL, Bambara RA.

J Biol Chem. 2006 Dec 15;281(50):38565-72. Epub 2006 Oct 11.

Items per page

Supplemental Content

Write to the Help Desk