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1.

Frequent BRAF gain in low-grade diffuse gliomas with 1p/19q loss.

Kim YH, Nonoguchi N, Paulus W, Brokinkel B, Keyvani K, Sure U, Wrede K, Mariani L, Giangaspero F, Tanaka Y, Nakazato Y, Vital A, Mittelbronn M, Perry A, Ohgaki H.

Brain Pathol. 2012 Nov;22(6):834-40. doi: 10.1111/j.1750-3639.2012.00601.x. Epub 2012 Jun 1.

PMID:
22568401
2.

Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549-BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification.

Gierke M, Sperveslage J, Schwab D, Beschorner R, Ebinger M, Schuhmann MU, Schittenhelm J.

J Cancer Res Clin Oncol. 2015 Jun 27. [Epub ahead of print]

PMID:
26115961
3.

Much debated controversies of diffuse low-grade gliomas.

Zadeh G, Khan OH, Vogelbaum M, Schiff D.

Neuro Oncol. 2015 Mar;17(3):323-6. doi: 10.1093/neuonc/nou368. No abstract available.

4.

Evidence-based clinical practice parameter guidelines for the treatment of adults with diffuse low grade glioma: introduction and methods.

Olson JJ, Kalkanis SN, Ryken TC.

J Neurooncol. 2015 Jun 25. [Epub ahead of print] No abstract available.

PMID:
26108657
5.

Molecular characterization of disseminated pilocytic astrocytomas.

Gessi M, Engels AC, Lambert S, Rothämel T, von Hornstein S, Collins VP, Denkhaus D, Gnekow A, Pietsch T.

Neuropathol Appl Neurobiol. 2015 Jun 18. doi: 10.1111/nan.12256. [Epub ahead of print]

PMID:
26084390
6.

KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.

Becker AP, Scapulatempo-Neto C, Carloni AC, Paulino A, Sheren J, Aisner DL, Musselwhite E, Clara C, Machado HR, Oliveira RS, Neder L, Varella-Garcia M, Reis RM.

J Neuropathol Exp Neurol. 2015 Jul;74(7):743-54. doi: 10.1097/NEN.0000000000000213.

7.

Multiple Molecular Data Sets and the Classification of Adult Diffuse Gliomas.

Ellison DW.

N Engl J Med. 2015 Jun 25;372(26):2555-7. doi: 10.1056/NEJMe1506813. Epub 2015 Jun 10. No abstract available.

PMID:
26061754
8.

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T Jr, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG Jr, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, Wolinsky Y, Bell S, Rosenberg M, Stewart C, Huang F, Grimsby JL, Radenbaugh AJ, Zhang J.

N Engl J Med. 2015 Jun 25;372(26):2481-98. doi: 10.1056/NEJMoa1402121. Epub 2015 Jun 10.

PMID:
26061751
9.

Molecular Markers in Low-Grade Glioma-Toward Tumor Reclassification.

Olar A, Sulman EP.

Semin Radiat Oncol. 2015 Jul;25(3):155-163. doi: 10.1016/j.semradonc.2015.02.006. Epub 2015 Feb 23. Review.

PMID:
26050585
10.

Biomarker-driven diagnosis of diffuse gliomas.

Appin CL, Brat DJ.

Mol Aspects Med. 2015 May 21. pii: S0098-2997(15)00032-1. doi: 10.1016/j.mam.2015.05.002. [Epub ahead of print] Review.

PMID:
26004297
11.

Therapeutic Targets in Pilocytic Astrocytoma Based on Genetic Analysis.

Reis GF, Tihan T.

Semin Pediatr Neurol. 2015 Mar;22(1):23-27. doi: 10.1016/j.spen.2014.12.001. Epub 2014 Dec 10. Review.

PMID:
25976257
12.

Diagnostic, prognostic and predictive relevance of molecular markers in gliomas.

Brandner S, von Deimling A.

Neuropathol Appl Neurobiol. 2015 May 5. doi: 10.1111/nan.12246. [Epub ahead of print]

PMID:
25944653
13.

Biphasic IDH1 phenotype in a diffusely infiltrating glioma: implications for pathogenesis, treatment and prognosis.

Odia Y, Varma H, Tsankova NM.

Clin Neuropathol. 2015 Apr 24. [Epub ahead of print]

PMID:
25907263
14.

Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma.

Taha H, Yehia M, Mahmoud M, El-Beltagy M, Ghabriel M, El-Naggar S.

Clin Transl Med. 2015 Mar 3;4:10. doi: 10.1186/s40169-015-0052-7. eCollection 2015.

15.

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.

Bergthold G, Bandopadhayay P, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A, Santagata S, Wen PY, Goumnerova LC, Ligon AH, Stiles C, Segal R, Golub T, Grill J, Ligon KL, Chan JA, Kieran MW, Beroukhim R.

Neuro Oncol. 2015 Mar 29. pii: nov045. [Epub ahead of print]

PMID:
25825052
16.

The BRAF kinase domain promotes the development of gliomas in vivo.

Shin CH, Grossmann AH, Holmen SL, Robinson JP.

Genes Cancer. 2015 Jan;6(1-2):9-18.

17.

BRAF and CDKN2A mutations in secondary high-grade glioma.

Boughton B.

Lancet Oncol. 2015 May;16(5):e201. doi: 10.1016/S1470-2045(15)70145-2. Epub 2015 Mar 27. No abstract available.

PMID:
25818616
18.

Molecular signalling pathways in canine gliomas.

Boudreau CE, York D, Higgins RJ, LeCouteur RA, Dickinson PJ.

Vet Comp Oncol. 2015 Mar 25. doi: 10.1111/vco.12147. [Epub ahead of print]

PMID:
25808605
19.

Oncogenic KIAA1549-BRAF fusion with activation of the MAPK/ERK pathway in pediatric oligodendrogliomas.

Kumar A, Pathak P, Purkait S, Faruq M, Jha P, Mallick S, Suri V, Sharma MC, Suri A, Sarkar C.

Cancer Genet. 2015 Mar;208(3):91-5. doi: 10.1016/j.cancergen.2015.01.009. Epub 2015 Feb 20.

PMID:
25794445
20.

Pilocytic astrocytoma: pathology, molecular mechanisms and markers.

Collins VP, Jones DT, Giannini C.

Acta Neuropathol. 2015 Jun;129(6):775-88. doi: 10.1007/s00401-015-1410-7. Epub 2015 Mar 20.

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