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Results: 1 to 20 of 102

1.

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration.

Sun Z, Miller RA, Patel RT, Chen J, Dhir R, Wang H, Zhang D, Graham MJ, Unterman TG, Shulman GI, Sztalryd C, Bennett MJ, Ahima RS, Birnbaum MJ, Lazar MA.

Nat Med. 2012 Jun;18(6):934-42. doi: 10.1038/nm.2744.

PMID:
22561686
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism.

Feng D, Liu T, Sun Z, Bugge A, Mullican SE, Alenghat T, Liu XS, Lazar MA.

Science. 2011 Mar 11;331(6022):1315-9. doi: 10.1126/science.1198125.

PMID:
21393543
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.

Bezy O, Tran TT, Pihlajamäki J, Suzuki R, Emanuelli B, Winnay J, Mori MA, Haas J, Biddinger SB, Leitges M, Goldfine AB, Patti ME, King GL, Kahn CR.

J Clin Invest. 2011 Jun;121(6):2504-17. doi: 10.1172/JCI46045. Epub 2011 May 16.

PMID:
21576825
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet.

Wada T, Kenmochi H, Miyashita Y, Sasaki M, Ojima M, Sasahara M, Koya D, Tsuneki H, Sasaoka T.

Endocrinology. 2010 May;151(5):2040-9. doi: 10.1210/en.2009-0869. Epub 2010 Mar 8.

PMID:
20211973
[PubMed - indexed for MEDLINE]
5.

CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism.

Peterson JM, Seldin MM, Wei Z, Aja S, Wong GW.

Am J Physiol Gastrointest Liver Physiol. 2013 Aug 1;305(3):G214-24. doi: 10.1152/ajpgi.00102.2013. Epub 2013 Jun 6.

PMID:
23744740
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation.

Kenerson HL, Yeh MM, Yeung RS.

PLoS One. 2011 Mar 29;6(3):e18075. doi: 10.1371/journal.pone.0018075.

PMID:
21479224
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance.

Ma Y, Huang Y, Yan L, Gao M, Liu D.

Pharm Res. 2013 May;30(5):1447-57. doi: 10.1007/s11095-013-0986-7. Epub 2013 Feb 1.

PMID:
23371517
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Liver-specific inhibition of ChREBP improves hepatic steatosis and insulin resistance in ob/ob mice.

Dentin R, Benhamed F, Hainault I, Fauveau V, Foufelle F, Dyck JR, Girard J, Postic C.

Diabetes. 2006 Aug;55(8):2159-70.

PMID:
16873678
[PubMed - indexed for MEDLINE]
Free Article
9.

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice.

Wang Q, Jiang L, Wang J, Li S, Yu Y, You J, Zeng R, Gao X, Rui L, Li W, Liu Y.

Hepatology. 2009 Apr;49(4):1166-75. doi: 10.1002/hep.22774.

PMID:
19177596
[PubMed - indexed for MEDLINE]
10.

Ping-tang Recipe () improves insulin resistance and attenuates hepatic steatosis in high-fat diet-induced obese rats.

Yang SY, Zhao NJ, Li XJ, Zhang HJ, Chen KJ, Li CD.

Chin J Integr Med. 2012 Apr;18(4):262-8. doi: 10.1007/s11655-012-1023-0. Epub 2012 Mar 30.

PMID:
22457136
[PubMed - indexed for MEDLINE]
11.

Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.

Abu-Elheiga L, Wu H, Gu Z, Bressler R, Wakil SJ.

J Biol Chem. 2012 Apr 6;287(15):12578-88. doi: 10.1074/jbc.M111.309559. Epub 2012 Feb 23.

PMID:
22362781
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

PMID:
19798065
[PubMed - indexed for MEDLINE]
13.

Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-Ay mice.

Tsuchida T, Shiraishi M, Ohta T, Sakai K, Ishii S.

Metabolism. 2012 Jul;61(7):944-53. doi: 10.1016/j.metabol.2011.10.023. Epub 2011 Dec 7.

PMID:
22154323
[PubMed - indexed for MEDLINE]
14.

Porcine adiponectin receptor 1 transgene resists high-fat/sucrose diet-induced weight gain, hepatosteatosis and insulin resistance in mice.

Liu BH, Lin YY, Wang YC, Huang CW, Chen CC, Wu SC, Mersmann HJ, Cheng WT, Ding ST.

Exp Anim. 2013;62(4):347-60.

PMID:
24172199
[PubMed - indexed for MEDLINE]
Free Article
15.

FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.

Wang C, Chi Y, Li J, Miao Y, Li S, Su W, Jia S, Chen Z, Du S, Zhang X, Zhou Y, Wu W, Zhu M, Wang Z, Yang H, Xu G, Wang S, Yang J, Guan Y.

Hepatology. 2014 May;59(5):1779-90. doi: 10.1002/hep.26945. Epub 2014 Mar 27.

PMID:
24806753
[PubMed - indexed for MEDLINE]
16.

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.

Wiedemann MS, Wueest S, Item F, Schoenle EJ, Konrad D.

Am J Physiol Endocrinol Metab. 2013 Aug 1;305(3):E388-95. doi: 10.1152/ajpendo.00179.2013. Epub 2013 Jun 4.

PMID:
23736545
[PubMed - indexed for MEDLINE]
Free Article
17.

Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis.

Monsénégo J, Mansouri A, Akkaoui M, Lenoir V, Esnous C, Fauveau V, Tavernier V, Girard J, Prip-Buus C.

J Hepatol. 2012 Mar;56(3):632-9. doi: 10.1016/j.jhep.2011.10.008. Epub 2011 Oct 25.

PMID:
22037024
[PubMed - indexed for MEDLINE]
18.

Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice.

Asai A, Chou PM, Bu HF, Wang X, Rao MS, Jiang A, DiDonato CJ, Tan XD.

Am J Physiol Gastrointest Liver Physiol. 2014 Mar;306(6):G496-504. doi: 10.1152/ajpgi.00291.2013. Epub 2014 Jan 16.

PMID:
24436353
[PubMed - indexed for MEDLINE]
19.

Effects of excess dietary iron and fat on glucose and lipid metabolism.

Choi JS, Koh IU, Lee HJ, Kim WH, Song J.

J Nutr Biochem. 2013 Sep;24(9):1634-44. doi: 10.1016/j.jnutbio.2013.02.004. Epub 2013 May 2.

PMID:
23643521
[PubMed - indexed for MEDLINE]
20.

Circadian epigenomic remodeling and hepatic lipogenesis: lessons from HDAC3.

Sun Z, Feng D, Everett LJ, Bugge A, Lazar MA.

Cold Spring Harb Symp Quant Biol. 2011;76:49-55. doi: 10.1101/sqb.2011.76.011494. Epub 2011 Sep 6. Review.

PMID:
21900149
[PubMed - indexed for MEDLINE]
Free PMC Article

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