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Results: 1 to 20 of 97

1.

Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation.

Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET.

Physiol Genomics. 2012 Jun 15;44(12):638-50. doi: 10.1152/physiolgenomics.00028.2012. Epub 2012 May 1.

PMID:
22548738
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis.

Fuhrken PG, Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET.

J Biol Chem. 2008 Jun 6;283(23):15589-600. doi: 10.1074/jbc.M801923200. Epub 2008 Apr 8.

PMID:
18397889
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation.

Fuhrken PG, Chen C, Miller WM, Papoutsakis ET.

Exp Hematol. 2007 Mar;35(3):476-489.

PMID:
17309828
[PubMed - indexed for MEDLINE]
4.

Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells.

Kawasaki A, Matsumura I, Miyagawa Ji, Ezoe S, Tanaka H, Terada Y, Tatsuka M, Machii T, Miyazaki H, Furukawa Y, Kanakura Y.

J Cell Biol. 2001 Jan 22;152(2):275-87.

PMID:
11266445
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization.

Lindsey S, Papoutsakis ET.

Br J Haematol. 2011 Feb;152(4):469-84. doi: 10.1111/j.1365-2141.2010.08548.x. Epub 2011 Jan 12.

PMID:
21226706
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Overexpression of cyclin D1 in the Dami megakaryocytic cell line causes growth arrest.

Wilhide CC, Van Dang C, Dipersio J, Kenedy AA, Bray PF.

Blood. 1995 Jul 1;86(1):294-304.

PMID:
7795236
[PubMed - indexed for MEDLINE]
Free Article
7.

Heterologous expression of the transcriptional regulator escargot inhibits megakaryocytic endomitosis.

Ballester A, Frampton J, Vilaboa N, Calés C.

J Biol Chem. 2001 Nov 16;276(46):43413-8. Epub 2001 Aug 9.

PMID:
11498537
[PubMed - indexed for MEDLINE]
Free Article
8.

A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis.

Chen C, Fuhrken PG, Huang LT, Apostolidis P, Wang M, Paredes CJ, Miller WM, Papoutsakis ET.

BMC Genomics. 2007 Oct 22;8:384.

PMID:
17953764
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.

Matsumura I, Tanaka H, Kawasaki A, Odajima J, Daino H, Hashimoto K, Wakao H, Nakajima K, Kato T, Miyazaki H, Kanakura Y.

J Biol Chem. 2000 Feb 25;275(8):5553-9.

PMID:
10681535
[PubMed - indexed for MEDLINE]
Free Article
10.

Pim-1 induced polyploidy but did not affect megakaryocytic differentiation of K562 cells and CD34+ cells from cord blood.

Jung YJ, Chae HC, Seoh JY, Ryu KH, Park HK, Kim YJ, Woo SY.

Eur J Haematol. 2007 Feb;78(2):131-8.

PMID:
17313559
[PubMed - indexed for MEDLINE]
11.

The involvement of human-nuc gene in polyploidization of K562 cell line.

Cavalloni G, Danè A, Piacibello W, Bruno S, Lamas E, Bréchot C, Aglietta M.

Exp Hematol. 2000 Dec;28(12):1432-40.

PMID:
11146165
[PubMed - indexed for MEDLINE]
12.

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis.

Fuhrken PG, Chen C, Apostolidis PA, Wang M, Miller WM, Papoutsakis ET.

Physiol Genomics. 2008 Apr 22;33(2):159-69. doi: 10.1152/physiolgenomics.00127.2007. Epub 2008 Feb 5.

PMID:
18252802
[PubMed - indexed for MEDLINE]
Free Article
13.

Role of p21(Cip1/Waf1) in cell-cycle exit of endomitotic megakaryocytes.

Baccini V, Roy L, Vitrat N, Chagraoui H, Sabri S, Le Couedic JP, Debili N, Wendling F, Vainchenker W.

Blood. 2001 Dec 1;98(12):3274-82.

PMID:
11719364
[PubMed - indexed for MEDLINE]
Free Article
14.

Embryonic stem cell differentiation system for evaluating gene functions involved in physiological megakaryocytic differentiation.

Okada Y, Yonekura M, Watanabe M, Nakai T, Wakimura A, Shimizu M, Kamikawa Y, Kitayama M, Kitajima K, Aird WC, Doi T.

Biochem Biophys Res Commun. 2012 Mar 16;419(3):477-81. doi: 10.1016/j.bbrc.2012.02.021. Epub 2012 Feb 10.

PMID:
22342727
[PubMed - indexed for MEDLINE]
15.

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

Jacquel A, Herrant M, Defamie V, Belhacene N, Colosetti P, Marchetti S, Legros L, Deckert M, Mari B, Cassuto JP, Hofman P, Auberger P.

Oncogene. 2006 Feb 2;25(5):781-94.

PMID:
16186797
[PubMed - indexed for MEDLINE]
16.

Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization.

Bermejo R, Vilaboa N, Calés C.

Mol Biol Cell. 2002 Nov;13(11):3989-4000.

PMID:
12429841
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Stathmin expression and megakaryocyte differentiation: a potential role in polyploidy.

Rubin CI, French DL, Atweh GF.

Exp Hematol. 2003 May;31(5):389-97.

PMID:
12763137
[PubMed - indexed for MEDLINE]
18.

Role of tumor suppressor p53 in megakaryopoiesis and platelet function.

Apostolidis PA, Woulfe DS, Chavez M, Miller WM, Papoutsakis ET.

Exp Hematol. 2012 Feb;40(2):131-42.e4. doi: 10.1016/j.exphem.2011.10.006. Epub 2011 Oct 21.

PMID:
22024107
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

p53 apoptotic response to DNA damage dependent on bcl2 but not bax in head and neck squamous cell carcinoma lines.

Crowe DL, Sinha UK.

Head Neck. 2006 Jan;28(1):15-23.

PMID:
16302195
[PubMed - indexed for MEDLINE]
20.

Bcl-x is a regulatory factor of apoptosis and differentiation in megakaryocytic lineage cells.

Terui Y, Furukawa Y, Kikuchi J, Iwase S, Hatake K, Miura Y.

Exp Hematol. 1998 Mar;26(3):236-44.

PMID:
9502620
[PubMed - indexed for MEDLINE]

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