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Infusion of hemolyzed red blood cells within peripheral blood stem cell grafts in patients with and without sickle cell disease.

Fitzhugh CD, Unno H, Hathaway V, Coles WA, Link ME, Weitzel RP, Zhao X, Wright EC, Stroncek DF, Kato GJ, Hsieh MM, Tisdale JF.

Blood. 2012 Jun 14;119(24):5671-3. doi: 10.1182/blood-2011-11-392654. Epub 2012 Apr 30.


Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation.

Minniti CP, Sable C, Campbell A, Rana S, Ensing G, Dham N, Onyekwere O, Nouraie M, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR.

Haematologica. 2009 Mar;94(3):340-7. doi: 10.3324/haematol.13812. Epub 2009 Feb 11.


[Relevant low toxicities with rhG-CSF mobilized and cryopreserved autologous peripheral blood stem cell return infusions in children].

Wang JW, Tang SQ, Lü SG, Ran CR, Yang G, Liu Y, Gao XN.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Apr;15(2):404-7. Chinese.


Low bone mass density is associated with hemolysis in Brazilian patients with sickle cell disease.

Baldanzi G, Traina F, Marques Neto JF, Santos AO, Ramos CD, Saad ST.

Clinics (Sao Paulo). 2011;66(5):801-5.


Human sickle cell blood modulates endothelial heme oxygenase activity: effects on vascular adhesion and reactivity.

Bains SK, Foresti R, Howard J, Atwal S, Green CJ, Motterlini R.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):305-12. doi: 10.1161/ATVBAHA.109.196360. Epub 2009 Dec 3.


Hemolysis-associated priapism in sickle cell disease.

Nolan VG, Wyszynski DF, Farrer LA, Steinberg MH.

Blood. 2005 Nov 1;106(9):3264-7. Epub 2005 Jun 28.


Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy.

Kato GJ, Gladwin MT.

JAMA. 2008 Dec 10;300(22):2638-46. doi: 10.1001/jama.2008.598. Review.


Mechanisms of stroke in sickle cell disease: sickle erythrocytes decrease cerebral blood flow in rats after nitric oxide synthase inhibition.

French JA 2nd, Kenny D, Scott JP, Hoffmann RG, Wood JD, Hudetz AG, Hillery CA.

Blood. 1997 Jun 15;89(12):4591-9.


Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom.

Sachdev V, Kato GJ, Gibbs JS, Barst RJ, Machado RF, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli EM, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JG 6th, Hannoush H, Goldsmith JC, Gladwin MT, Gordeuk VR; Walk-PHASST Investigators.

Circulation. 2011 Sep 27;124(13):1452-60. doi: 10.1161/CIRCULATIONAHA.111.032920. Epub 2011 Sep 6.


Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease.

Kato GJ, McGowan V, Machado RF, Little JA, Taylor J 6th, Morris CR, Nichols JS, Wang X, Poljakovic M, Morris SM Jr, Gladwin MT.

Blood. 2006 Mar 15;107(6):2279-85. Epub 2005 Nov 15.


Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes.

Kato GJ, Gladwin MT, Steinberg MH.

Blood Rev. 2007 Jan;21(1):37-47. Epub 2006 Nov 7. Review.


Delayed hemolytic transfusion reactions in sickle cell disease: simultaneous destruction of recipients' red cells.

King KE, Shirey RS, Lankiewicz MW, Young-Ramsaran J, Ness PM.

Transfusion. 1997 Apr;37(4):376-81.


Increased plasma EPO and MIP-1 alpha are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts.

Labonté L, Li Y, Yang L, Gillingham A, Halpenny M, Giulivi A, Sills T, Evans K, Zanke B, Allan DS.

Exp Hematol. 2009 Jun;37(6):673-8. doi: 10.1016/j.exphem.2009.02.010.


Sickle cell anemia as a rheologic disease.

Horne MK 3rd.

Am J Med. 1981 Feb;70(2):288-98. Review.


Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain.

Taylor JG 6th, Nolan VG, Mendelsohn L, Kato GJ, Gladwin MT, Steinberg MH.

PLoS One. 2008 May 7;3(5):e2095. doi: 10.1371/journal.pone.0002095.


Sickle cell disease and nitric oxide: a paradigm shift?

Mack AK, Kato GJ.

Int J Biochem Cell Biol. 2006;38(8):1237-43. Epub 2006 Feb 17. Review.


The lollipop with strawberry aroma may be promising in reduction of infusion-related nausea and vomiting during the infusion of cryopreserved peripheral blood stem cells.

Ozdemir E, Akgedik K, Akdogan S, Kansu E.

Biol Blood Marrow Transplant. 2008 Dec;14(12):1425-8. doi: 10.1016/j.bbmt.2008.09.010.


The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.

Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT; Walk-PHASST Investigators and Patients.

Haematologica. 2013 Mar;98(3):464-72. doi: 10.3324/haematol.2012.068965. Epub 2012 Sep 14.

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