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Results: 1 to 20 of 134

Similar articles for PubMed (Select 22532571)

1.

Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).

Wang G, Dinkins M, He Q, Zhu G, Poirier C, Campbell A, Mayer-Proschel M, Bieberich E.

J Biol Chem. 2012 Jun 15;287(25):21384-95. doi: 10.1074/jbc.M112.340513. Epub 2012 Apr 24.

2.

Exosome reduction in vivo is associated with lower amyloid plaque load in the 5XFAD mouse model of Alzheimer's disease.

Dinkins MB, Dasgupta S, Wang G, Zhu G, Bieberich E.

Neurobiol Aging. 2014 Aug;35(8):1792-800. doi: 10.1016/j.neurobiolaging.2014.02.012. Epub 2014 Feb 15.

PMID:
24650793
3.

Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway.

Lee JT, Xu J, Lee JM, Ku G, Han X, Yang DI, Chen S, Hsu CY.

J Cell Biol. 2004 Jan 5;164(1):123-31.

4.

Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi.

Gu L, Huang B, Shen W, Gao L, Ding Z, Wu H, Guo J.

J Neuroinflammation. 2013 Sep 3;10:109. doi: 10.1186/1742-2094-10-109.

5.

Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction.

Meyers-Needham M, Lewis JA, Gencer S, Sentelle RD, Saddoughi SA, Clarke CJ, Hannun YA, Norell H, da Palma TM, Nishimura M, Kraveka JM, Khavandgar Z, Murshed M, Cevik MO, Ogretmen B.

Mol Cancer Ther. 2012 May;11(5):1092-102. doi: 10.1158/1535-7163.MCT-11-0705. Epub 2012 Mar 27.

6.

Long-chain ceramide is elevated in presenilin 1 (PS1M146V) mouse brain and induces apoptosis in PS1 astrocytes.

Wang G, Silva J, Dasgupta S, Bieberich E.

Glia. 2008 Mar;56(4):449-56. doi: 10.1002/glia.20626.

PMID:
18205190
7.

Sphingomyelinase dependent apoptosis following treatment of pancreatic beta-cells with amyloid peptides Abeta(1-42) or IAPP.

Zhang Y, Ranta F, Tang C, Shumilina E, Mahmud H, Föller M, Ullrich S, Häring HU, Lang F.

Apoptosis. 2009 Jul;14(7):878-89. doi: 10.1007/s10495-009-0364-4.

PMID:
19488858
9.

Sphingolipid-modulated exosome secretion promotes clearance of amyloid-β by microglia.

Yuyama K, Sun H, Mitsutake S, Igarashi Y.

J Biol Chem. 2012 Mar 30;287(14):10977-89. doi: 10.1074/jbc.M111.324616. Epub 2012 Feb 2.

10.

Ceramide-dependent caspase 3 activation is prevented by coenzyme Q from plasma membrane in serum-deprived cells.

Navas P, Fernandez-Ayala DM, Martin SF, Lopez-Lluch G, De Caboa R, Rodriguez-Aguilera JC, Villalba JM.

Free Radic Res. 2002 Apr;36(4):369-74.

PMID:
12069099
11.

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells.

Wang G, Silva J, Krishnamurthy K, Tran E, Condie BG, Bieberich E.

J Biol Chem. 2005 Jul 15;280(28):26415-24. Epub 2005 May 18.

12.

A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.

Cinq-Frais C, Coatrieux C, Grazide MH, Hannun YA, Nègre-Salvayre A, Salvayre R, Augé N.

Biochim Biophys Acta. 2013 Aug;1831(8):1344-56. doi: 10.1016/j.bbalip.2013.04.014. Epub 2013 May 4.

PMID:
23651497
13.

Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.

Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):639-46. doi: 10.1165/rcmb.2007-0274OC. Epub 2008 Jan 10.

14.

Role of c-jun expression increased by heat shock- and ceramide-activated caspase-3 in HL-60 cell apoptosis. Possible involvement of ceramide in heat shock-induced apoptosis.

Kondo T, Matsuda T, Kitano T, Takahashi A, Tashima M, Ishikura H, Umehara H, Domae N, Uchiyama T, Okazaki T.

J Biol Chem. 2000 Mar 17;275(11):7668-76.

15.
16.

Reactive nitrogen and oxygen species activate different sphingomyelinases to induce apoptosis in airway epithelial cells.

Castillo SS, Levy M, Thaikoottathil JV, Goldkorn T.

Exp Cell Res. 2007 Jul 15;313(12):2680-6. Epub 2007 Apr 6.

PMID:
17498692
17.

Ceramide pathways modulate ethanol-induced cell death in astrocytes.

Pascual M, Valles SL, Renau-Piqueras J, Guerri C.

J Neurochem. 2003 Dec;87(6):1535-45.

PMID:
14713309
18.

TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis.

Dumitru CA, Gulbins E.

Oncogene. 2006 Sep 14;25(41):5612-25. Epub 2006 Apr 24.

PMID:
16636669
19.

Ceramide plays a prominent role in MDA-7/IL-24-induced cancer-specific apoptosis.

Sauane M, Su ZZ, Dash R, Liu X, Norris JS, Sarkar D, Lee SG, Allegood JC, Dent P, Spiegel S, Fisher PB.

J Cell Physiol. 2010 Mar;222(3):546-55. doi: 10.1002/jcp.21969.

PMID:
19937735
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