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Results: 1 to 20 of 101

1.

ETS-dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells.

von Brandenstein M, Schlosser M, Richter C, Depping R, Fries JW.

Life Sci. 2012 Oct 15;91(13-14):562-71. doi: 10.1016/j.lfs.2012.04.014. Epub 2012 Apr 12.

PMID:
22521293
[PubMed - indexed for MEDLINE]
Free Article
2.

Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.

Takeuchi S, Takahashi A, Motoi N, Yoshimoto S, Tajima T, Yamakoshi K, Hirao A, Yanagi S, Fukami K, Ishikawa Y, Sone S, Hara E, Ohtani N.

Cancer Res. 2010 Nov 15;70(22):9381-90. doi: 10.1158/0008-5472.CAN-10-0801. Epub 2010 Nov 9.

PMID:
21062974
[PubMed - indexed for MEDLINE]
Free Article
3.

p53 Deficiency leads to compensatory up-regulation of p16INK4a.

Leong WF, Chau JF, Li B.

Mol Cancer Res. 2009 Mar;7(3):354-60. doi: 10.1158/1541-7786.MCR-08-0373. Epub 2009 Feb 24.

PMID:
19240179
[PubMed - indexed for MEDLINE]
Free Article
4.

Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1).

Obata M, Imamura E, Yoshida Y, Goto J, Kishibe K, Yasuda A, Ogawa K.

Mol Carcinog. 2001 Sep;32(1):9-18.

PMID:
11568971
[PubMed - indexed for MEDLINE]
5.

Expression of senescence-related genes in human corneal endothelial cells.

Song Z, Wang Y, Xie L, Zang X, Yin H.

Mol Vis. 2008 Jan 29;14:161-70.

PMID:
18334933
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Id1 is down-regulated by hepatocyte growth factor via ERK-dependent and ERK-independent signaling pathways, leading to increased expression of p16INK4a in hepatoma cells.

Ushio K, Hashimoto T, Kitamura N, Tanaka T.

Mol Cancer Res. 2009 Jul;7(7):1179-88. doi: 10.1158/1541-7786.MCR-08-0289. Epub 2009 Jun 30.

PMID:
19567783
[PubMed - indexed for MEDLINE]
Free Article
8.

p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.

Zheng QH, Ma LW, Zhu WG, Zhang ZY, Tong TJ.

J Cell Biochem. 2006 Aug 1;98(5):1230-48.

PMID:
16514663
[PubMed - indexed for MEDLINE]
9.

Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.

Kriegl L, Neumann J, Vieth M, Greten FR, Reu S, Jung A, Kirchner T.

Mod Pathol. 2011 Jul;24(7):1015-22. doi: 10.1038/modpathol.2011.43. Epub 2011 Mar 18.

PMID:
21423154
[PubMed - indexed for MEDLINE]
Free Article
10.

Two mechanisms underlying the loss of p16(Ink4a) function are associated with distinct tumorigenic consequences for WS MEFs escaping from senescence.

Wu X, Jia S, Zhang X, Si X, Tang W, Luo Y.

Mech Ageing Dev. 2012 Aug;133(8):549-55. doi: 10.1016/j.mad.2012.07.002. Epub 2012 Jul 16.

PMID:
22813853
[PubMed - indexed for MEDLINE]
11.

Mechanisms of MEOX1 and MEOX2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells.

Douville JM, Cheung DY, Herbert KL, Moffatt T, Wigle JT.

PLoS One. 2011;6(12):e29099. doi: 10.1371/journal.pone.0029099. Epub 2011 Dec 20.

PMID:
22206000
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells.

Enomoto K, Mimura T, Harris DL, Joyce NC.

Invest Ophthalmol Vis Sci. 2006 Oct;47(10):4330-40.

PMID:
17003423
[PubMed - indexed for MEDLINE]
Free Article
13.

Bmi-1 reduction plays a key role in physiological and premature aging of primary human keratinocytes.

Cordisco S, Maurelli R, Bondanza S, Stefanini M, Zambruno G, Guerra L, Dellambra E.

J Invest Dermatol. 2010 Apr;130(4):1048-62. doi: 10.1038/jid.2009.355. Epub 2009 Nov 12.

PMID:
19907431
[PubMed - indexed for MEDLINE]
Free Article
14.

The expression of p16INK4a tumor suppressor is upregulated by human cytomegalovirus infection and required for optimal viral replication.

Zannetti C, Mondini M, De Andrea M, Caposio P, Hara E, Peters G, Gribaudo G, Gariglio M, Landolfo S.

Virology. 2006 May 25;349(1):79-86. Epub 2006 Feb 28.

PMID:
16504234
[PubMed - indexed for MEDLINE]
Free Article
15.

Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function.

Foster JS, Henley DC, Bukovsky A, Seth P, Wimalasena J.

Mol Cell Biol. 2001 Feb;21(3):794-810.

PMID:
11154267
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.

Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, Ohashi Y, Sharrocks AD, Peters G, Hara E.

Nature. 2001 Feb 22;409(6823):1067-70.

PMID:
11234019
[PubMed - indexed for MEDLINE]
19.

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.

Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Jun 4;279(23):24745-56. Epub 2004 Mar 25.

PMID:
15044451
[PubMed - indexed for MEDLINE]
Free Article
20.

Expression of p53, p21WAF1/CIP1, p16INK4A and Ki-67 proteins in serous ovarian tumors.

Buchynska LG, Nesina IP, Yurchenko NP, Bilyk OO, Grinkevych VN, Svintitsky VS.

Exp Oncol. 2007 Mar;29(1):49-53.

PMID:
17431389
[PubMed - indexed for MEDLINE]

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