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Items: 1 to 20 of 186

1.

Cell therapy limits myofibroblast differentiation and structural cardiac remodeling: basic fibroblast growth factor-mediated paracrine mechanism.

Fedak PW, Bai L, Turnbull J, Ngu J, Narine K, Duff HJ.

Circ Heart Fail. 2012 May 1;5(3):349-56. doi: 10.1161/CIRCHEARTFAILURE.111.965889. Epub 2012 Apr 16.

2.

Antifibrotic response of cardiac fibroblasts in hypertensive hearts through enhanced TIMP-1 expression by basic fibroblast growth factor.

Kinoshita T, Ishikawa Y, Arita M, Akishima-Fukasawa Y, Fujita K, Inomata N, Suzuki T, Namiki A, Mikami T, Ikeda T, Yamazaki J, Ishii T, Akasaka Y.

Cardiovasc Pathol. 2014 Mar-Apr;23(2):92-100. doi: 10.1016/j.carpath.2013.11.001. Epub 2013 Nov 14.

PMID:
24322055
3.

Basic fibroblast growth factor inhibits ventricular remodeling in Dahl salt-sensitive hypertensive rats.

Suzuki T, Akasaka Y, Namiki A, Ito K, Ishikawa Y, Yamazaki J, Ishii T.

J Hypertens. 2008 Dec;26(12):2436-44. doi: 10.1097/HJH.0b013e328312c889.

PMID:
19008723
4.

Fibroblast growth factor-2 regulates human cardiac myofibroblast-mediated extracellular matrix remodeling.

Svystonyuk DA, Ngu JM, Mewhort HE, Lipon BD, Teng G, Guzzardi DG, Malik G, Belke DD, Fedak PW.

J Transl Med. 2015 May 7;13:147. doi: 10.1186/s12967-015-0510-4.

5.

Expression of the tissue inhibitor of metalloproteinase-3 by transplanted VSMCs modifies heart structure and function after myocardial infarction.

Jia ZB, Tian H, Kang K, Miao HZ, Liu KY, Jiang SL, Wang LP.

Transpl Immunol. 2014 May;30(4):149-58. doi: 10.1016/j.trim.2014.03.006. Epub 2014 Apr 12.

PMID:
24727088
6.

Cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy are ameliorated by alpha-lipoic acid.

Li CJ, Lv L, Li H, Yu DM.

Cardiovasc Diabetol. 2012 Jun 19;11:73. doi: 10.1186/1475-2840-11-73.

7.

Epicardial infarct repair with basic fibroblast growth factor-enhanced CorMatrix-ECM biomaterial attenuates postischemic cardiac remodeling.

Mewhort HE, Turnbull JD, Meijndert HC, Ngu JM, Fedak PW.

J Thorac Cardiovasc Surg. 2014 May;147(5):1650-9. doi: 10.1016/j.jtcvs.2013.08.005. Epub 2013 Sep 26.

PMID:
24075463
8.
9.

Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.

Ngu JM, Teng G, Meijndert HC, Mewhort HE, Turnbull JD, Stetler-Stevenson WG, Fedak PW.

Cardiovasc Pathol. 2014 Nov-Dec;23(6):335-43. doi: 10.1016/j.carpath.2014.06.003. Epub 2014 Jun 21.

PMID:
25060386
10.

Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress.

Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z.

Circulation. 2011 Nov 8;124(19):2094-105. doi: 10.1161/CIRCULATIONAHA.111.030338. Epub 2011 Oct 10.

11.

TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation.

Kandalam V, Basu R, Abraham T, Wang X, Soloway PD, Jaworski DM, Oudit GY, Kassiri Z.

Circ Res. 2010 Mar 5;106(4):796-808. doi: 10.1161/CIRCRESAHA.109.209189. Epub 2010 Jan 7.

12.

Estrogen improves TIMP-MMP balance and collagen distribution in volume-overloaded hearts of ovariectomized females.

Voloshenyuk TG, Gardner JD.

Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R683-93. doi: 10.1152/ajpregu.00162.2010. Epub 2010 May 26.

13.

Cell transplantation preserves matrix homeostasis: a novel paracrine mechanism.

Fedak PW, Szmitko PE, Weisel RD, Altamentova SM, Nili N, Ohno N, Verma S, Fazel S, Strauss BH, Li RK.

J Thorac Cardiovasc Surg. 2005 Nov;130(5):1430-9. Epub 2005 Oct 13.

PMID:
16256799
14.

Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction.

Tang YL, Zhao Q, Qin X, Shen L, Cheng L, Ge J, Phillips MI.

Ann Thorac Surg. 2005 Jul;80(1):229-36; discussion 236-7.

PMID:
15975372
15.

Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress.

Garrett Q, Khaw PT, Blalock TD, Schultz GS, Grotendorst GR, Daniels JT.

Invest Ophthalmol Vis Sci. 2004 Apr;45(4):1109-16.

PMID:
15037576
16.

Basic fibroblast growth factor antagonizes transforming growth factor-beta1-induced smooth muscle gene expression through extracellular signal-regulated kinase 1/2 signaling pathway activation.

Kawai-Kowase K, Sato H, Oyama Y, Kanai H, Sato M, Doi H, Kurabayashi M.

Arterioscler Thromb Vasc Biol. 2004 Aug;24(8):1384-90. Epub 2004 Jun 24.

17.

Inhibiting matrix metalloproteinase by cell-based timp-3 gene transfer effectively treats acute and chronic ischemic cardiomyopathy.

Tian H, Huang ML, Liu KY, Jia ZB, Sun L, Jiang SL, Liu W, McDonald Kinkaid HY, Wu J, Li RK.

Cell Transplant. 2012;21(5):1039-53. doi: 10.3727/096368911X601000. Epub 2011 Sep 23.

PMID:
21944319
18.

Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction.

Mias C, Lairez O, Trouche E, Roncalli J, Calise D, Seguelas MH, Ordener C, Piercecchi-Marti MD, Auge N, Salvayre AN, Bourin P, Parini A, Cussac D.

Stem Cells. 2009 Nov;27(11):2734-43. doi: 10.1002/stem.169.

19.

Cell-based gene therapy modifies matrix remodeling after a myocardial infarction in tissue inhibitor of matrix metalloproteinase-3-deficient mice.

Angoulvant D, Fazel S, Weisel RD, Lai TY, Fedak PW, Chen L, Rafati S, Seneviratne CK, Degousee N, Li RK.

J Thorac Cardiovasc Surg. 2009 Feb;137(2):471-80. doi: 10.1016/j.jtcvs.2008.08.031.

PMID:
19185172
20.

Cardiac myofibroblast differentiation is attenuated by alpha(3) integrin blockade: potential role in post-MI remodeling.

Bryant JE, Shamhart PE, Luther DJ, Olson ER, Koshy JC, Costic DJ, Mohile MV, Dockry M, Doane KJ, Meszaros JG.

J Mol Cell Cardiol. 2009 Feb;46(2):186-92. doi: 10.1016/j.yjmcc.2008.10.022. Epub 2008 Nov 7.

PMID:
19041328
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