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Results: 1 to 20 of 123

1.

miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay.

Djuranovic S, Nahvi A, Green R.

Science. 2012 Apr 13;336(6078):237-40. doi: 10.1126/science.1215691.

PMID:
22499947
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

What comes first: translational repression or mRNA degradation? The deepening mystery of microRNA function.

Hu W, Coller J.

Cell Res. 2012 Sep;22(9):1322-4. doi: 10.1038/cr.2012.80. Epub 2012 May 22.

PMID:
22613951
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression.

Zdanowicz A, Thermann R, Kowalska J, Jemielity J, Duncan K, Preiss T, Darzynkiewicz E, Hentze MW.

Mol Cell. 2009 Sep 24;35(6):881-8. doi: 10.1016/j.molcel.2009.09.009.

PMID:
19782035
[PubMed - indexed for MEDLINE]
Free Article
4.

Deadenylation is a widespread effect of miRNA regulation.

Eulalio A, Huntzinger E, Nishihara T, Rehwinkel J, Fauser M, Izaurralde E.

RNA. 2009 Jan;15(1):21-32. doi: 10.1261/rna.1399509. Epub 2008 Nov 24.

PMID:
19029310
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish.

Bazzini AA, Lee MT, Giraldez AJ.

Science. 2012 Apr 13;336(6078):233-7. doi: 10.1126/science.1215704. Epub 2012 Mar 15.

PMID:
22422859
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targets.

Huntzinger E, Kuzuoglu-Öztürk D, Braun JE, Eulalio A, Wohlbold L, Izaurralde E.

Nucleic Acids Res. 2013 Jan;41(2):978-94. doi: 10.1093/nar/gks1078. Epub 2012 Nov 21.

PMID:
23172285
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system.

Wakiyama M, Takimoto K, Ohara O, Yokoyama S.

Genes Dev. 2007 Aug 1;21(15):1857-62. Erratum in: Genes Dev. 2007 Oct 1;21(19):2509.

PMID:
17671087
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells.

Béthune J, Artus-Revel CG, Filipowicz W.

EMBO Rep. 2012 Aug;13(8):716-23. doi: 10.1038/embor.2012.82. Epub 2012 Jun 8.

PMID:
22677978
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo.

Rouget C, Papin C, Boureux A, Meunier AC, Franco B, Robine N, Lai EC, Pelisson A, Simonelig M.

Nature. 2010 Oct 28;467(7319):1128-32. doi: 10.1038/nature09465. Epub 2010 Oct 17.

PMID:
20953170
[PubMed - indexed for MEDLINE]
10.

miRNA repression of translation in vitro takes place during 43S ribosomal scanning.

Ricci EP, Limousin T, Soto-Rifo R, Rubilar PS, Decimo D, Ohlmann T.

Nucleic Acids Res. 2013 Jan 7;41(1):586-98. doi: 10.1093/nar/gks1076. Epub 2012 Nov 17.

PMID:
23161679
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N.

Mol Cell. 2009 Sep 24;35(6):868-80. doi: 10.1016/j.molcel.2009.08.004. Epub 2009 Aug 27.

PMID:
19716330
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

MicroRNAs mediate gene silencing via multiple different pathways in drosophila.

Fukaya T, Tomari Y.

Mol Cell. 2012 Dec 28;48(6):825-36. doi: 10.1016/j.molcel.2012.09.024. Epub 2012 Nov 1.

PMID:
23123195
[PubMed - indexed for MEDLINE]
Free Article
13.

The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release.

Zekri L, Huntzinger E, Heimstädt S, Izaurralde E.

Mol Cell Biol. 2009 Dec;29(23):6220-31. doi: 10.1128/MCB.01081-09. Epub 2009 Sep 21.

PMID:
19797087
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

Beilharz TH, Humphreys DT, Clancy JL, Thermann R, Martin DI, Hentze MW, Preiss T.

PLoS One. 2009 Aug 27;4(8):e6783. doi: 10.1371/journal.pone.0006783.

PMID:
19710908
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.

Behm-Ansmant I, Rehwinkel J, Izaurralde E.

Cold Spring Harb Symp Quant Biol. 2006;71:523-30. Review.

PMID:
17381335
[PubMed - indexed for MEDLINE]
16.

Argonaute-mediated translational repression (and activation).

Iwasaki S, Tomari Y.

Fly (Austin). 2009 Jul-Sep;3(3):204-6. Epub 2009 Jul 14. Review.

PMID:
19556851
[PubMed - indexed for MEDLINE]
Free Article
17.

Molecular insights into microRNA-mediated translational repression in plants.

Iwakawa HO, Tomari Y.

Mol Cell. 2013 Nov 21;52(4):591-601. doi: 10.1016/j.molcel.2013.10.033.

PMID:
24267452
[PubMed - indexed for MEDLINE]
18.

A role for microRNAs in the Drosophila circadian clock.

Kadener S, Menet JS, Sugino K, Horwich MD, Weissbein U, Nawathean P, Vagin VV, Zamore PD, Nelson SB, Rosbash M.

Genes Dev. 2009 Sep 15;23(18):2179-91. doi: 10.1101/gad.1819509. Epub 2009 Aug 20.

PMID:
19696147
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Nucleolin mediates microRNA-directed CSF-1 mRNA deadenylation but increases translation of CSF-1 mRNA.

Woo HH, Baker T, Laszlo C, Chambers SK.

Mol Cell Proteomics. 2013 Jun;12(6):1661-77. doi: 10.1074/mcp.M112.025288. Epub 2013 Mar 7.

PMID:
23471483
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.

Eulalio A, Rehwinkel J, Stricker M, Huntzinger E, Yang SF, Doerks T, Dorner S, Bork P, Boutros M, Izaurralde E.

Genes Dev. 2007 Oct 15;21(20):2558-70. Epub 2007 Sep 27.

PMID:
17901217
[PubMed - indexed for MEDLINE]
Free PMC Article

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