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Items: 1 to 20 of 372

1.

Evaluation of in vitro and in vivo anti-melanogenic activity of a newly synthesized strong tyrosinase inhibitor (E)-3-(2,4 dihydroxybenzylidene)pyrrolidine-2,5-dione (3-DBP).

Chung KW, Park YJ, Choi YJ, Park MH, Ha YM, Uehara Y, Yoon JH, Chun P, Moon HR, Chung HY.

Biochim Biophys Acta. 2012 Jul;1820(7):962-9. doi: 10.1016/j.bbagen.2012.03.018. Epub 2012 Apr 3.

PMID:
22498140
2.

Inhibitory effects of Sargassum polycystum on tyrosinase activity and melanin formation in B16F10 murine melanoma cells.

Chan YY, Kim KH, Cheah SH.

J Ethnopharmacol. 2011 Oct 11;137(3):1183-8. doi: 10.1016/j.jep.2011.07.050. Epub 2011 Jul 26.

PMID:
21810462
3.

Design, synthesis, and evaluation of (E)-N-substituted benzylidene-aniline derivatives as tyrosinase inhibitors.

Bae SJ, Ha YM, Park YJ, Park JY, Song YM, Ha TK, Chun P, Moon HR, Chung HY.

Eur J Med Chem. 2012 Nov;57:383-90. doi: 10.1016/j.ejmech.2012.09.026. Epub 2012 Sep 23.

PMID:
23149255
4.

Characterization of a small molecule inhibitor of melanogenesis that inhibits tyrosinase activity and scavenges nitric oxide (NO).

Chung KW, Jeong HO, Jang EJ, Choi YJ, Kim DH, Kim SR, Lee KJ, Lee HJ, Chun P, Byun Y, Moon HR, Chung HY.

Biochim Biophys Acta. 2013 Oct;1830(10):4752-61. doi: 10.1016/j.bbagen.2013.06.002. Epub 2013 Jun 12.

PMID:
23769841
5.

Suppression of melanogenesis by a newly synthesized compound, MHY966 via the nitric oxide/protein kinase G signaling pathway in murine skin.

Choi YJ, Uehara Y, Park JY, Chung KW, Ha YM, Kim JM, Song YM, Chun P, Park JW, Moon HR, Chung HY.

J Dermatol Sci. 2012 Dec;68(3):164-71. doi: 10.1016/j.jdermsci.2012.09.014. Epub 2012 Oct 3.

PMID:
23088959
6.

Anti-melanogenic effect of (Z)-5-(2,4-dihydroxybenzylidene) thiazolidine-2,4-dione, a novel tyrosinase inhibitor.

Kim SH, Ha YM, Moon KM, Choi YJ, Park YJ, Jeong HO, Chung KW, Lee HJ, Chun P, Moon HR, Chung HY.

Arch Pharm Res. 2013 Oct;36(10):1189-97. doi: 10.1007/s12272-013-0184-5. Epub 2013 Jul 1.

PMID:
23812774
7.

Design and synthesis of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as novel tyrosinase inhibitors.

Ha YM, Park YJ, Kim JA, Park D, Park JY, Lee HJ, Lee JY, Moon HR, Chung HY.

Eur J Med Chem. 2012 Mar;49:245-52. doi: 10.1016/j.ejmech.2012.01.019. Epub 2012 Jan 24.

PMID:
22301213
8.

A newly synthesized, potent tyrosinase inhibitor: 5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol.

Choi J, Bae SJ, Ha YM, No JK, Lee EK, Lee JS, Song S, Lee H, Suh H, Yu BP, Chung HY.

Bioorg Med Chem Lett. 2010 Aug 15;20(16):4882-4. doi: 10.1016/j.bmcl.2010.06.087. Epub 2010 Jun 19. Erratum in: Bioorg Med Chem Lett. 2011 Jan 1;21(1):606.

PMID:
20619644
9.
10.

Synthesis and anti-melanogenic activity of hydroxyphenyl benzyl ether analogues.

Sapkota K, Roh E, Lee E, Ha EM, Yang JH, Lee ES, Kwon Y, Kim Y, Na Y.

Bioorg Med Chem. 2011 Apr 1;19(7):2168-75. doi: 10.1016/j.bmc.2011.02.044. Epub 2011 Feb 26.

PMID:
21429753
11.

Design, synthesis, and anti-melanogenic effects of (E)-2-benzoyl-3-(substituted phenyl)acrylonitriles.

Yun HY, Kim do H, Son S, Ullah S, Kim SJ, Kim YJ, Yoo JW, Jung Y, Chun P, Moon HR.

Drug Des Devel Ther. 2015 Aug 4;9:4259-68. doi: 10.2147/DDDT.S89976. eCollection 2015.

12.

Inhibitory effect of phlorotannins isolated from Ecklonia cava on mushroom tyrosinase activity and melanin formation in mouse B16F10 melanoma cells.

Yoon NY, Eom TK, Kim MM, Kim SK.

J Agric Food Chem. 2009 May 27;57(10):4124-9. doi: 10.1021/jf900006f. Epub 2009 Apr 10.

PMID:
19361156
13.

Inhibitory effects of arbutin on melanin biosynthesis of alpha-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues.

Lim YJ, Lee EH, Kang TH, Ha SK, Oh MS, Kim SM, Yoon TJ, Kang C, Park JH, Kim SY.

Arch Pharm Res. 2009 Mar;32(3):367-73. doi: 10.1007/s12272-009-1309-8. Epub 2009 Apr 23.

PMID:
19387580
14.

Down-regulation of tyrosinase expression by acetylsalicylic acid in murine B16 melanoma.

Sato K, Takahashi H, Iraha R, Toriyama M.

Biol Pharm Bull. 2008 Jan;31(1):33-7.

15.

Evaluation of the inhibition of mushroom tyrosinase and cellular tyrosinase activities of oxyresveratrol: comparison with mulberroside A.

Kim JK, Park KT, Lee HS, Kim M, Lim YH.

J Enzyme Inhib Med Chem. 2012 Aug;27(4):495-503. doi: 10.3109/14756366.2011.598866. Epub 2011 Aug 10.

PMID:
21827364
16.

1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane, a novel tyrosinase inhibitor with strong depigmenting effects.

Nesterov A, Zhao J, Minter D, Hertel C, Ma W, Abeysinghe P, Hong M, Jia Q.

Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1292-6.

17.

Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase.

Thanigaimalai P, Lee KC, Sharma VK, Joo C, Cho WJ, Roh E, Kim Y, Jung SH.

Bioorg Med Chem Lett. 2011 Nov 15;21(22):6824-8. doi: 10.1016/j.bmcl.2011.09.024. Epub 2011 Sep 13.

PMID:
21978680
18.

Characterization of a novel tyrosinase inhibitor, (2RS,4R)-2-(2,4-dihydroxyphenyl)thiazolidine-4-carboxylic acid (MHY384).

Han YK, Park YJ, Ha YM, Park D, Lee JY, Lee N, Yoon JH, Moon HR, Chung HY.

Biochim Biophys Acta. 2012 Apr;1820(4):542-9. doi: 10.1016/j.bbagen.2012.01.001. Epub 2012 Jan 9.

PMID:
22251576
19.

Ascorbic acid increases the activity and synthesis of tyrosinase in B16F10 cells through activation of p38 mitogen-activated protein kinase.

Lee SA, Son YO, Kook SH, Choi KC, Lee JC.

Arch Dermatol Res. 2011 Nov;303(9):669-78. doi: 10.1007/s00403-011-1158-4. Epub 2011 Jun 11.

PMID:
21667118
20.

4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: a potent, new tyrosinase inhibitor.

Ha YM, Chung SW, Song S, Lee H, Suh H, Chung HY.

Biol Pharm Bull. 2007 Sep;30(9):1711-5.

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