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Items: 1 to 20 of 153


Opioid receptor heteromers in analgesia.

Costantino CM, Gomes I, Stockton SD, Lim MP, Devi LA.

Expert Rev Mol Med. 2012 Apr 10;14:e9. doi: 10.1017/erm.2012.5. Review.


Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism.

Milan-Lobo L, Enquist J, van Rijn RM, Whistler JL.

PLoS One. 2013;8(3):e58362. doi: 10.1371/journal.pone.0058362. Epub 2013 Mar 15.


Augmentation of spinal morphine analgesia and inhibition of tolerance by low doses of mu- and delta-opioid receptor antagonists.

Abul-Husn NS, Sutak M, Milne B, Jhamandas K.

Br J Pharmacol. 2007 Jul;151(6):877-87. Epub 2007 May 14.


Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor trafficking.

Milan-Lobo L, Whistler JL.

J Pharmacol Exp Ther. 2011 Jun;337(3):868-75. doi: 10.1124/jpet.111.179093. Epub 2011 Mar 21.


Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities.

Fujita W, Gomes I, Devi LA.

Br J Pharmacol. 2015 Jan;172(2):375-87. doi: 10.1111/bph.12663. Epub 2014 Jul 1. Review.


Agonists at the δ-opioid receptor modify the binding of µ-receptor agonists to the µ-δ receptor hetero-oligomer.

Kabli N, Martin N, Fan T, Nguyen T, Hasbi A, Balboni G, O'Dowd BF, George SR.

Br J Pharmacol. 2010 Nov;161(5):1122-36. doi: 10.1111/j.1476-5381.2010.00944.x.


Prolonged morphine treatment targets delta opioid receptors to neuronal plasma membranes and enhances delta-mediated antinociception.

Cahill CM, Morinville A, Lee MC, Vincent JP, Collier B, Beaudet A.

J Neurosci. 2001 Oct 1;21(19):7598-607.


Opiate antagonist prevents μ- and δ-opiate receptor dimerization to facilitate ability of agonist to control ethanol-altered natural killer cell functions and mammary tumor growth.

Sarkar DK, Sengupta A, Zhang C, Boyadjieva N, Murugan S.

J Biol Chem. 2012 May 11;287(20):16734-47. doi: 10.1074/jbc.M112.347583. Epub 2012 Mar 27.


Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand.

Parenti C, Turnaturi R, Aricò G, Marrazzo A, Prezzavento O, Ronsisvalle S, Scoto GM, Ronsisvalle G, Pasquinucci L.

Life Sci. 2012 Jun 27;90(25-26):957-61. doi: 10.1016/j.lfs.2012.04.041. Epub 2012 May 11.


A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia.

Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, Devi LA.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5135-9. Epub 2004 Mar 24.


Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment.

Wang D, Sun X, Sadee W.

J Pharmacol Exp Ther. 2007 May;321(2):544-52. Epub 2007 Jan 31.

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