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Results: 1 to 20 of 170

1.

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system.

Karlsson H, Fryknäs M, Larsson R, Nygren P.

Exp Cell Res. 2012 Aug 1;318(13):1577-85. doi: 10.1016/j.yexcr.2012.03.026. Epub 2012 Apr 2.

PMID:
22487097
[PubMed - indexed for MEDLINE]
2.

Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids.

Herrmann R, Fayad W, Schwarz S, Berndtsson M, Linder S.

J Biomol Screen. 2008 Jan;13(1):1-8. Epub 2007 Nov 26.

PMID:
18040052
[PubMed - indexed for MEDLINE]
3.

A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids.

Markovitz-Bishitz Y, Tauber Y, Afrimzon E, Zurgil N, Sobolev M, Shafran Y, Deutsch A, Howitz S, Deutsch M.

Biomaterials. 2010 Nov;31(32):8436-44. doi: 10.1016/j.biomaterials.2010.07.050. Epub 2010 Aug 7.

PMID:
20692698
[PubMed - indexed for MEDLINE]
4.

Identification of agents that induce apoptosis of multicellular tumour spheroids: enrichment for mitotic inhibitors with hydrophobic properties.

Fayad W, Rickardson L, Haglund C, Olofsson MH, D'Arcy P, Larsson R, Linder S, Fryknäs M.

Chem Biol Drug Des. 2011 Oct;78(4):547-57. doi: 10.1111/j.1747-0285.2011.01170.x. Epub 2011 Jul 29.

PMID:
21726416
[PubMed - indexed for MEDLINE]
5.

Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341.

Frankel A, Man S, Elliott P, Adams J, Kerbel RS.

Clin Cancer Res. 2000 Sep;6(9):3719-28.

PMID:
10999766
[PubMed - indexed for MEDLINE]
Free Article
6.

AlgiMatrix™ based 3D cell culture system as an in-vitro tumor model for anticancer studies.

Godugu C, Patel AR, Desai U, Andey T, Sams A, Singh M.

PLoS One. 2013;8(1):e53708. doi: 10.1371/journal.pone.0053708. Epub 2013 Jan 18.

PMID:
23349734
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors.

Steadman K, Stein WD, Litman T, Yang SX, Abu-Asab M, Dutcher SK, Bates S.

Cell Cycle. 2008 Mar 15;7(6):818-29. Epub 2008 Jan 9.

PMID:
18239467
[PubMed - indexed for MEDLINE]
Free Article
8.

Cytotoxicity of adriamycin in MGH-U1 cells grown as monolayer cultures, spheroids, and xenografts in immune-deprived mice.

Erlichman C, Vidgen D.

Cancer Res. 1984 Nov;44(11):5369-75.

PMID:
6488191
[PubMed - indexed for MEDLINE]
Free Article
9.

The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines.

Fujiwara D, Kato K, Nohara S, Iwanuma Y, Kajiyama Y.

Biochem Biophys Res Commun. 2013 May 17;434(4):773-8. doi: 10.1016/j.bbrc.2013.04.008. Epub 2013 Apr 18.

PMID:
23602898
[PubMed - indexed for MEDLINE]
10.

Development of an in vitro multicellular tumor spheroid model using microencapsulation and its application in anticancer drug screening and testing.

Zhang X, Wang W, Yu W, Xie Y, Zhang X, Zhang Y, Ma X.

Biotechnol Prog. 2005 Jul-Aug;21(4):1289-96.

PMID:
16080713
[PubMed - indexed for MEDLINE]
11.

Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge?

Friedrich J, Ebner R, Kunz-Schughart LA.

Int J Radiat Biol. 2007 Nov-Dec;83(11-12):849-71. Review.

PMID:
18058370
[PubMed - indexed for MEDLINE]
12.

Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids.

Nicholson KM, Bibby MC, Phillips RM.

Eur J Cancer. 1997 Jul;33(8):1291-8.

PMID:
9301458
[PubMed - indexed for MEDLINE]
13.

Isolation and characterization of spheroid cells from the HT29 colon cancer cell line.

Fan X, Ouyang N, Teng H, Yao H.

Int J Colorectal Dis. 2011 Oct;26(10):1279-85. doi: 10.1007/s00384-011-1248-y. Epub 2011 Jun 14.

PMID:
21670985
[PubMed - indexed for MEDLINE]
14.

Enhancement of drug efflux activity via MDR1 protein by spheroid culture of human hepatic cancer cells.

Oshikata A, Matsushita T, Ueoka R.

J Biosci Bioeng. 2011 May;111(5):590-3. doi: 10.1016/j.jbiosc.2011.01.006. Epub 2011 Feb 26.

PMID:
21354366
[PubMed - indexed for MEDLINE]
15.

Changes in subcellular distribution of topoisomerase IIalpha correlate with etoposide resistance in multicell spheroids and xenograft tumors.

Oloumi A, MacPhail SH, Johnston PJ, Banáth JP, Olive PL.

Cancer Res. 2000 Oct 15;60(20):5747-53.

PMID:
11059769
[PubMed - indexed for MEDLINE]
Free Article
16.

Alginate-based microfluidic system for tumor spheroid formation and anticancer agent screening.

Chen MC, Gupta M, Cheung KC.

Biomed Microdevices. 2010 Aug;12(4):647-54. doi: 10.1007/s10544-010-9417-2.

PMID:
20237849
[PubMed - indexed for MEDLINE]
17.

A multicellular spheroid-based drug sensitivity test by scanning electrochemical microscopy.

Torisawa YS, Takagi A, Shiku H, Yasukawa T, Matsue T.

Oncol Rep. 2005 Jun;13(6):1107-12.

PMID:
15870929
[PubMed - indexed for MEDLINE]
18.

New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells.

Botchkina GI, Zuniga ES, Das M, Wang Y, Wang H, Zhu S, Savitt AG, Rowehl RA, Leyfman Y, Ju J, Shroyer K, Ojima I.

Mol Cancer. 2010 Jul 14;9:192. doi: 10.1186/1476-4598-9-192.

PMID:
20630067
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

On-chip anticancer drug test of regular tumor spheroids formed in microwells by a distributive microchannel network.

Kim C, Bang JH, Kim YE, Lee SH, Kang JY.

Lab Chip. 2012 Oct 21;12(20):4135-42.

PMID:
22864534
[PubMed - indexed for MEDLINE]
20.

Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids.

Lobjois V, Frongia C, Jozan S, Truchet I, Valette A.

Eur J Cancer. 2009 Sep;45(13):2402-11. doi: 10.1016/j.ejca.2009.05.026. Epub 2009 Jun 22.

PMID:
19553104
[PubMed - indexed for MEDLINE]

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