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Items: 1 to 20 of 113

1.

Kinase signaling dysfunction in Parkinson's disease: a reverse genetic approach in Drosophila.

Huang Y, Shenoy S, Lu B, Liu W, Li C.

J Neurogenet. 2012 Jun;26(2):158-67. doi: 10.3109/01677063.2012.672499. Epub 2012 Apr 10. Review.

PMID:
22486164
2.

Mouse models for LRRK2 Parkinson's disease.

Xu Q, Shenoy S, Li C.

Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S186-9. doi: 10.1016/S1353-8020(11)70058-X. Review.

PMID:
22166430
3.

The roles of kinases in familial Parkinson's disease.

Cookson MR, Dauer W, Dawson T, Fon EA, Guo M, Shen J.

J Neurosci. 2007 Oct 31;27(44):11865-8. Review.

4.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M.

Nature. 2006 Jun 29;441(7097):1162-6. Epub 2006 May 3.

PMID:
16672981
5.

On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies.

Daniëls V, Baekelandt V, Taymans JM.

Neurosignals. 2011;19(1):1-15. doi: 10.1159/000324488. Epub 2011 Mar 23. Review.

PMID:
21430363
6.

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.

Venderova K, Kabbach G, Abdel-Messih E, Zhang Y, Parks RJ, Imai Y, Gehrke S, Ngsee J, Lavoie MJ, Slack RS, Rao Y, Zhang Z, Lu B, Haque ME, Park DS.

Hum Mol Genet. 2009 Nov 15;18(22):4390-404. doi: 10.1093/hmg/ddp394. Epub 2009 Aug 19.

7.

[Animal models for familial Parkinson's disease].

Takahashi R.

Rinsho Shinkeigaku. 2007 Nov;47(11):938-40. Japanese.

PMID:
18210841
8.

Genetic mutations and functions of PINK1.

Kawajiri S, Saiki S, Sato S, Hattori N.

Trends Pharmacol Sci. 2011 Oct;32(10):573-80. doi: 10.1016/j.tips.2011.06.001. Epub 2011 Jul 23. Review.

PMID:
21784538
9.
10.

A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's disease.

Nishioka K, Kefi M, Jasinska-Myga B, Wider C, Vilariño-Güell C, Ross OA, Heckman MG, Middleton LT, Ishihara-Paul L, Gibson RA, Amouri R, Ben Yahmed S, Ben Sassi S, Zouari M, El Euch G, Farrer MJ, Hentati F.

J Neurol Neurosurg Psychiatry. 2010 Apr;81(4):391-5. doi: 10.1136/jnnp.2009.185231. Epub 2009 Sep 2.

PMID:
19726410
11.

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.

Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B.

EMBO Mol Med. 2009 May;1(2):99-111. doi: 10.1002/emmm.200900006.

12.

Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease.

Büeler H.

Exp Neurol. 2009 Aug;218(2):235-46. doi: 10.1016/j.expneurol.2009.03.006. Epub 2009 Mar 18. Review.

PMID:
19303005
13.

Pink1 suppresses alpha-synuclein-induced phenotypes in a Drosophila model of Parkinson's disease.

Todd AM, Staveley BE.

Genome. 2008 Dec;51(12):1040-6. doi: 10.1139/G08-085.

PMID:
19088817
14.

Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1).

Mills RD, Sim CH, Mok SS, Mulhern TD, Culvenor JG, Cheng HC.

J Neurochem. 2008 Apr;105(1):18-33. doi: 10.1111/j.1471-4159.2008.05249.x. Epub 2008 Jan 23. Review.

15.

Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease.

Lee BD, Dawson VL, Dawson TM.

Trends Pharmacol Sci. 2012 Jul;33(7):365-73. doi: 10.1016/j.tips.2012.04.001. Epub 2012 May 9. Review.

16.

LRRK2 in Parkinson's disease: in vivo models and approaches for understanding pathogenic roles.

Yue Z.

FEBS J. 2009 Nov;276(22):6445-54. doi: 10.1111/j.1742-4658.2009.07343.x. Epub 2009 Oct 5. Review.

17.

Understanding the molecular causes of Parkinson's disease.

Wood-Kaczmar A, Gandhi S, Wood NW.

Trends Mol Med. 2006 Nov;12(11):521-8. Epub 2006 Oct 5. Review.

PMID:
17027339
18.

[Molecular genetics of PINK1].

Funayama M, Hattori N.

Brain Nerve. 2007 Aug;59(8):831-8. Review. Japanese.

PMID:
17713119
19.

PINK1 protein in normal human brain and Parkinson's disease.

Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T.

Brain. 2006 Jul;129(Pt 7):1720-31. Epub 2006 May 15.

20.

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.

Liu W, Acín-Peréz R, Geghman KD, Manfredi G, Lu B, Li C.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12920-4. doi: 10.1073/pnas.1107332108. Epub 2011 Jul 18.

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