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Results: 1 to 20 of 117

1.

Structure-activity relationships of α-, β(1)-, γ-, and δ-tomatine and tomatidine against human breast (MDA-MB-231), gastric (KATO-III), and prostate (PC3) cancer cells.

Choi SH, Ahn JB, Kozukue N, Kim HJ, Nishitani Y, Zhang L, Mizuno M, Levin CE, Friedman M.

J Agric Food Chem. 2012 Apr 18;60(15):3891-9. doi: 10.1021/jf3003027. Epub 2012 Apr 6.

PMID:
22482398
[PubMed - indexed for MEDLINE]
2.

Tomatine-containing green tomato extracts inhibit growth of human breast, colon, liver, and stomach cancer cells.

Friedman M, Levin CE, Lee SU, Kim HJ, Lee IS, Byun JO, Kozukue N.

J Agric Food Chem. 2009 Jul 8;57(13):5727-33. doi: 10.1021/jf900364j.

PMID:
19514731
[PubMed - indexed for MEDLINE]
3.

Alpha-tomatine synergises with paclitaxel to enhance apoptosis of androgen-independent human prostate cancer PC-3 cells in vitro and in vivo.

Lee ST, Wong PF, Hooper JD, Mustafa MR.

Phytomedicine. 2013 Nov 15;20(14):1297-305. doi: 10.1016/j.phymed.2013.07.002. Epub 2013 Aug 4.

PMID:
23920276
[PubMed - indexed for MEDLINE]
4.

Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells.

Lee KR, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M.

J Agric Food Chem. 2004 May 19;52(10):2832-9.

PMID:
15137822
[PubMed - indexed for MEDLINE]
5.

Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells.

Lee ST, Wong PF, Cheah SC, Mustafa MR.

PLoS One. 2011 Apr 26;6(4):e18915. doi: 10.1371/journal.pone.0018915.

PMID:
21541327
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

α-Tomatine suppresses invasion and migration of human non-small cell lung cancer NCI-H460 cells through inactivating FAK/PI3K/Akt signaling pathway and reducing binding activity of NF-κB.

Shieh JM, Cheng TH, Shi MD, Wu PF, Chen Y, Ko SC, Shih YW.

Cell Biochem Biophys. 2011 Jul;60(3):297-310. doi: 10.1007/s12013-011-9152-1.

PMID:
21264526
[PubMed - indexed for MEDLINE]
7.

Dual effects of plant steroidal alkaloids on Saccharomyces cerevisiae.

Simons V, Morrissey JP, Latijnhouwers M, Csukai M, Cleaver A, Yarrow C, Osbourn A.

Antimicrob Agents Chemother. 2006 Aug;50(8):2732-40.

PMID:
16870766
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Changes in free amino acid, phenolic, chlorophyll, carotenoid, and glycoalkaloid contents in tomatoes during 11 stages of growth and inhibition of cervical and lung human cancer cells by green tomato extracts.

Choi SH, Lee SH, Kim HJ, Lee IS, Kozukue N, Levin CE, Friedman M.

J Agric Food Chem. 2010 Jul 14;58(13):7547-56. doi: 10.1021/jf100162j.

PMID:
20560602
[PubMed - indexed for MEDLINE]
9.

Tomatidine and lycotetraose, hydrolysis products of alpha-tomatine by Fusarium oxysporum tomatinase, suppress induced defense responses in tomato cells.

Ito S, Eto T, Tanaka S, Yamauchi N, Takahara H, Ikeda T.

FEBS Lett. 2004 Jul 30;571(1-3):31-4.

PMID:
15280013
[PubMed - indexed for MEDLINE]
10.

Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice.

Friedman M, Henika PR, Mackey BE.

Food Chem Toxicol. 2003 Jan;41(1):61-71.

PMID:
12453729
[PubMed - indexed for MEDLINE]
11.

Effect of alpha-tomatine and tomatidine on membrane potential of frog embryos and active transport of ions in frog skin.

Blankemeyer JT, White JB, Stringer BK, Friedman M.

Food Chem Toxicol. 1997 Jul;35(7):639-46.

PMID:
9301646
[PubMed - indexed for MEDLINE]
12.

Analysis of tomato glycoalkaloids by liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Cataldi TR, Lelario F, Bufo SA.

Rapid Commun Mass Spectrom. 2005;19(21):3103-10.

PMID:
16200652
[PubMed - indexed for MEDLINE]
13.

Efficient synthesis of methyl lycotetraoside, the tetrasaccharide constituent of the tomato defence glycoalkaloid alpha-tomatine.

Jones NA, Nepogodiev SA, Field RA.

Org Biomol Chem. 2005 Sep 7;3(17):3201-6. Epub 2005 Jul 27.

PMID:
16106302
[PubMed - indexed for MEDLINE]
14.

Dehydrotomatine and alpha-tomatine content in tomato fruits and vegetative plant tissues.

Kozukue N, Han JS, Lee KR, Friedman M.

J Agric Food Chem. 2004 Apr 7;52(7):2079-83.

PMID:
15053555
[PubMed - indexed for MEDLINE]
15.

Feeding of potato, tomato and eggplant alkaloids affects food consumption and body and liver weights in mice.

Friedman M, Henika PR, Mackey BE.

J Nutr. 1996 Apr;126(4):989-99.

PMID:
8613903
[PubMed - indexed for MEDLINE]
Free Article
16.

Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells.

Lavie Y, Harel-Orbital T, Gaffield W, Liscovitch M.

Anticancer Res. 2001 Mar-Apr;21(2A):1189-94.

PMID:
11396162
[PubMed - indexed for MEDLINE]
17.

Tomato glycoalkaloids: role in the plant and in the diet.

Friedman M.

J Agric Food Chem. 2002 Oct 9;50(21):5751-80. Review.

PMID:
12358437
[PubMed - indexed for MEDLINE]
18.

In vitro anti-prostate cancer and ex vivo antiangiogenic activity of Vernonia guineensis Benth. (Asteraceae) tuber extracts.

Toyang NJ, Wabo HK, Ateh EN, Davis H, Tane P, Kimbu SF, Sondengam LB, Bryant J.

J Ethnopharmacol. 2012 Jun 14;141(3):866-71. doi: 10.1016/j.jep.2012.03.021. Epub 2012 Mar 23.

PMID:
22465590
[PubMed - indexed for MEDLINE]
19.

Tomatidine, a tomato sapogenol, ameliorates hyperlipidemia and atherosclerosis in apoE-deficient mice by inhibiting acyl-CoA:cholesterol acyl-transferase (ACAT).

Fujiwara Y, Kiyota N, Tsurushima K, Yoshitomi M, Horlad H, Ikeda T, Nohara T, Takeya M, Nagai R.

J Agric Food Chem. 2012 Mar 14;60(10):2472-9. doi: 10.1021/jf204197r. Epub 2012 Feb 28.

PMID:
22224814
[PubMed - indexed for MEDLINE]
20.

Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells.

Einbond LS, Wen-Cai Y, He K, Wu HA, Cruz E, Roller M, Kronenberg F.

Phytomedicine. 2008 Jun;15(6-7):504-11. Epub 2007 Nov 5.

PMID:
17980565
[PubMed - indexed for MEDLINE]
Free PMC Article

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