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Results: 1 to 20 of 97

1.

The maintenance of mitochondrial genetic stability is crucial during the oncogenic process.

Iglesias P, Salas A, Costoya JA.

Commun Integr Biol. 2012 Jan 1;5(1):34-8.

PMID:
22482007
[PubMed]
Free PMC Article
2.

The mitochondrial genome is a "genetic sanctuary" during the oncogenic process.

Seoane M, Mosquera-Miguel A, Gonzalez T, Fraga M, Salas A, Costoya JA.

PLoS One. 2011;6(8):e23327. doi: 10.1371/journal.pone.0023327. Epub 2011 Aug 17.

PMID:
21858071
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice.

Woo DK, Green PD, Santos JH, D'Souza AD, Walther Z, Martin WD, Christian BE, Chandel NS, Shadel GS.

Am J Pathol. 2012 Jan;180(1):24-31. doi: 10.1016/j.ajpath.2011.10.003. Epub 2011 Nov 3.

PMID:
22056359
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The causes of cancer revisited: "mitochondrial malignancy" and ROS-induced oncogenic transformation - why mitochondria are targets for cancer therapy.

Ralph SJ, Rodríguez-Enríquez S, Neuzil J, Saavedra E, Moreno-Sánchez R.

Mol Aspects Med. 2010 Apr;31(2):145-70. doi: 10.1016/j.mam.2010.02.008. Epub 2010 Mar 2. Review.

PMID:
20206201
[PubMed - indexed for MEDLINE]
5.

[Pathways for maintenance of mitochondrial DNA integrity and mitochondrial functions in cells exposed to ionizing radiation].

Gaziev AI.

Radiats Biol Radioecol. 2013 Mar-Apr;53(2):117-36. Review. Russian.

PMID:
23786028
[PubMed - indexed for MEDLINE]
6.

Part II. Mitochondrial mutational status of high nitric oxide adapted cell line BT-20 (BT-20-HNO) as it relates to human primary breast tumors.

De Vitto H, Mendonça BS, Elseth KM, Vesper BJ, Portari EA, Gallo CV, Paradise WA, Rumjanek FD, Radosevich JA.

Tumour Biol. 2013 Feb;34(1):337-47. doi: 10.1007/s13277-012-0555-4. Epub 2012 Dec 14.

PMID:
23238816
[PubMed - indexed for MEDLINE]
7.

Mitochondrial mutations in cancer.

Brandon M, Baldi P, Wallace DC.

Oncogene. 2006 Aug 7;25(34):4647-62. Review.

PMID:
16892079
[PubMed - indexed for MEDLINE]
8.

Respiratory function decline and DNA mutation in mitochondria, oxidative stress and altered gene expression during aging.

Wei YH, Wu SB, Ma YS, Lee HC.

Chang Gung Med J. 2009 Mar-Apr;32(2):113-32. Review.

PMID:
19403001
[PubMed - indexed for MEDLINE]
Free Article
9.

Radiation response of chemically derived mitochondrial DNA-deficient AG01522 human primary fibroblasts.

Nieri D, Fioramonti M, Berardinelli F, Leone S, Cherubini R, De Nadal V, Gerardi S, Moreno S, Nardacci R, Tanzarella C, Antoccia A.

Mutat Res. 2013 Aug 30;756(1-2):86-94. doi: 10.1016/j.mrgentox.2013.05.010. Epub 2013 May 27.

PMID:
23721903
[PubMed - indexed for MEDLINE]
10.

mtDNA Mutations and Their Role in Aging, Diseases and Forensic Sciences.

Zapico SC, Ubelaker DH.

Aging Dis. 2013 Oct 3;4(6):364-80. doi: 10.14336/AD.2013.0400364. Review.

PMID:
24307969
[PubMed]
Free PMC Article
11.

Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.

Lu J, Sharma LK, Bai Y.

Cell Res. 2009 Jul;19(7):802-15. doi: 10.1038/cr.2009.69. Review.

PMID:
19532122
[PubMed - indexed for MEDLINE]
12.

Melatonin-mitochondria interplay in health and disease.

Acuña Castroviejo D, López LC, Escames G, López A, García JA, Reiter RJ.

Curr Top Med Chem. 2011;11(2):221-40. Review.

PMID:
21244359
[PubMed - indexed for MEDLINE]
13.

Mitochondrial genome instability in human cancers.

Bianchi NO, Bianchi MS, Richard SM.

Mutat Res. 2001 Mar;488(1):9-23. Review.

PMID:
11223402
[PubMed - indexed for MEDLINE]
14.

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma.

Achanta G, Sasaki R, Feng L, Carew JS, Lu W, Pelicano H, Keating MJ, Huang P.

EMBO J. 2005 Oct 5;24(19):3482-92. Epub 2005 Sep 15.

PMID:
16163384
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.

Park JS, Sharma LK, Li H, Xiang R, Holstein D, Wu J, Lechleiter J, Naylor SL, Deng JJ, Lu J, Bai Y.

Hum Mol Genet. 2009 May 1;18(9):1578-89. doi: 10.1093/hmg/ddp069. Epub 2009 Feb 10.

PMID:
19208652
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress.

Lee HC, Wei YH.

Int J Biochem Cell Biol. 2005 Apr;37(4):822-34. Review.

PMID:
15694841
[PubMed - indexed for MEDLINE]
17.

An update on the mitochondrial-DNA mutation hypothesis of cell aging.

Miquel J.

Mutat Res. 1992 Sep;275(3-6):209-16. Review.

PMID:
1383762
[PubMed - indexed for MEDLINE]
18.

Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects.

Lyu BN, Ismailov SB, Ismailov B, Lyu MB.

Theor Biol Med Model. 2008 Nov 11;5:23. doi: 10.1186/1742-4682-5-23. Review.

PMID:
19014456
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis.

Lebedeva MA, Eaton JS, Shadel GS.

Biochim Biophys Acta. 2009 May;1787(5):328-34. doi: 10.1016/j.bbabio.2009.01.004. Epub 2009 Jan 20.

PMID:
19413947
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Suppression of mitochondrial DNA instability of autosomal dominant forms of progressive external ophthalmoplegia-associated ANT1 mutations in Podospora anserina.

El-Khoury R, Sainsard-Chanet A.

Genetics. 2009 Nov;183(3):861-71. doi: 10.1534/genetics.109.107813. Epub 2009 Aug 17.

PMID:
19687137
[PubMed - indexed for MEDLINE]
Free PMC Article

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