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Items: 1 to 20 of 99

1.

Imaging sites of infection using a 99mTc-labeled folate conjugate targeted to folate receptor positive macrophages.

Henne WA, Rothenbuhler R, Ayala-Lopez W, Xia W, Varghese B, Low PS.

Mol Pharm. 2012 May 7;9(5):1435-40. doi: 10.1021/mp3000138. Epub 2012 Apr 2.

PMID:
22468849
2.

Imaging of atherosclerosis in apoliprotein e knockout mice: targeting of a folate-conjugated radiopharmaceutical to activated macrophages.

Ayala-López W, Xia W, Varghese B, Low PS.

J Nucl Med. 2010 May;51(5):768-74. doi: 10.2967/jnumed.109.071324. Epub 2010 Apr 15.

3.

Exploratory study of 99mTc-EC20 imaging for identifying patients with folate receptor-positive solid tumors.

Fisher RE, Siegel BA, Edell SL, Oyesiku NM, Morgenstern DE, Messmann RA, Amato RJ.

J Nucl Med. 2008 Jun;49(6):899-906. doi: 10.2967/jnumed.107.049478. Epub 2008 May 15.

4.

Preclinical evaluation of (99m)Tc-EC20 for imaging folate receptor-positive tumors.

Reddy JA, Xu LC, Parker N, Vetzel M, Leamon CP.

J Nucl Med. 2004 May;45(5):857-66.

5.

In vitro and in vivo evaluation of (99m)Tc-DO3A-EA-Folate for receptor-mediated targeting of folate positive tumors.

Mishra G, Hazari PP, Kumar N, Mishra AK.

J Drug Target. 2011 Nov;19(9):761-9. doi: 10.3109/1061186X.2011.561857. Epub 2011 Mar 22.

PMID:
21425922
6.

A folate receptor-α-specific ligand that targets cancer tissue and not sites of inflammation.

Vaitilingam B, Chelvam V, Kularatne SA, Poh S, Ayala-Lopez W, Low PS.

J Nucl Med. 2012 Jul;53(7):1127-34. doi: 10.2967/jnumed.111.099390. Epub 2012 Jun 12.

7.

Synthesis and biological evaluation of EC20: a new folate-derived, (99m)Tc-based radiopharmaceutical.

Leamon CP, Parker MA, Vlahov IR, Xu LC, Reddy JA, Vetzel M, Douglas N.

Bioconjug Chem. 2002 Nov-Dec;13(6):1200-10.

PMID:
12440854
8.

Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of (99m)Tc-EC20 in xenografted and syngeneic tumor-bearing mice.

Müller C, Reddy JA, Leamon CP, Schibli R.

Mol Pharm. 2010 Apr 5;7(2):597-604. doi: 10.1021/mp900296k.

PMID:
20199053
9.

Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis.

Turk MJ, Breur GJ, Widmer WR, Paulos CM, Xu LC, Grote LA, Low PS.

Arthritis Rheum. 2002 Jul;46(7):1947-55.

10.

Synthesis and biological evaluation of receptor-based tumor imaging agent: (99m)Tc-folate-glucaric acid.

Onursal M, Lambrecht FY, Ozgur A.

Int J Pharm. 2011 Sep 15;416(1):288-92. doi: 10.1016/j.ijpharm.2011.07.010. Epub 2011 Jul 18.

PMID:
21782912
11.

Synthesis and in vitro/in vivo evaluation of 99mTc-labeled folate conjugates for folate receptor imaging.

Lu J, Pang Y, Xie F, Guo H, Li Y, Yang Z, Wang X.

Nucl Med Biol. 2011 May;38(4):557-65. doi: 10.1016/j.nucmedbio.2010.11.007. Epub 2011 Feb 4.

PMID:
21531293
12.

Imaging the folate receptor on cancer cells with 99mTc-etarfolatide: properties, clinical use, and future potential of folate receptor imaging.

Maurer AH, Elsinga P, Fanti S, Nguyen B, Oyen WJ, Weber WA.

J Nucl Med. 2014 May;55(5):701-4. doi: 10.2967/jnumed.113.133074. Epub 2014 Apr 14. Review.

13.

Use of folate-conjugated imaging agents to target alternatively activated macrophages in a murine model of asthma.

Shen J, Chelvam V, Cresswell G, Low PS.

Mol Pharm. 2013 May 6;10(5):1918-27. doi: 10.1021/mp3006962. Epub 2013 Apr 23.

PMID:
23641923
14.

A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages.

Xia W, Hilgenbrink AR, Matteson EL, Lockwood MB, Cheng JX, Low PS.

Blood. 2009 Jan 8;113(2):438-46. doi: 10.1182/blood-2008-04-150789. Epub 2008 Oct 24.

15.

Preclinical evaluation of novel organometallic 99mTc-folate and 99mTc-pteroate radiotracers for folate receptor-positive tumour targeting.

Müller C, Hohn A, Schubiger PA, Schibli R.

Eur J Nucl Med Mol Imaging. 2006 Sep;33(9):1007-16. Epub 2006 Jun 9.

PMID:
16763819
16.

EC145: a novel targeted agent for adenocarcinoma of the lung.

Pribble P, Edelman MJ.

Expert Opin Investig Drugs. 2012 May;21(5):755-61. doi: 10.1517/13543784.2012.671294. Epub 2012 Mar 30. Review.

PMID:
22462761
17.

Folate receptor-β imaging using 99mTc-folate to explore distribution of polarized macrophage populations in human atherosclerotic plaque.

Jager NA, Westra J, Golestani R, van Dam GM, Low PS, Tio RA, Slart RH, Boersma HH, Bijl M, Zeebregts CJ.

J Nucl Med. 2014 Dec;55(12):1945-51. doi: 10.2967/jnumed.114.143180. Epub 2014 Oct 30.

18.

In vivo imaging of folate receptor positive tumor xenografts using novel 68Ga-NODAGA-folate conjugates.

Fani M, Tamma ML, Nicolas GP, Lasri E, Medina C, Raynal I, Port M, Weber WA, Maecke HR.

Mol Pharm. 2012 May 7;9(5):1136-45. doi: 10.1021/mp200418f. Epub 2012 Apr 23.

PMID:
22497506
19.

Effects of antifolate drugs on the cellular uptake of radiofolates in vitro and in vivo.

Müller C, Brühlmeier M, Schubiger PA, Schibli R.

J Nucl Med. 2006 Dec;47(12):2057-64.

20.

Synthesis and evaluation of 99mTc(CO)(3)-DTPA-folate as a folate-receptor-targeted radiopharmaceutical.

Trump DP, Mathias CJ, Yang Z, Low PS, Marmion M, Green MA.

Nucl Med Biol. 2002 Jul;29(5):569-73.

PMID:
12088727
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