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Items: 1 to 20 of 89


Polycomb repressive complex 2 impedes intestinal cell terminal differentiation.

Benoit YD, Lepage MB, Khalfaoui T, Tremblay E, Basora N, Carrier JC, Gudas LJ, Beaulieu JF.

J Cell Sci. 2012 Jul 15;125(Pt 14):3454-63. doi: 10.1242/jcs.102061. Epub 2012 Mar 30.


The polycomb group protein Suz12 is required for embryonic stem cell differentiation.

Pasini D, Bracken AP, Hansen JB, Capillo M, Helin K.

Mol Cell Biol. 2007 May;27(10):3769-79. Epub 2007 Mar 5.


The histone H3K27 methylation mark regulates intestinal epithelial cell density-dependent proliferation and the inflammatory response.

Turgeon N, Blais M, Delabre JF, Asselin C.

J Cell Biochem. 2013 May;114(5):1203-15. doi: 10.1002/jcb.24463.


Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D, Hansen KH, Christensen J, Agger K, Cloos PA, Helin K.

Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008.


Polycomb group proteins and their roles in regulating stem cell development.

Huang BY, Pan XY, Li ZX, Wang ZC, Yu YS, Dou ZH.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Jun;34(3):281-5. doi: 10.3881/j.issn.1000-503X.2012.03.019. Review.


The polycomb repressive complex 2 is a potential target of SUMO modifications.

Riising EM, Boggio R, Chiocca S, Helin K, Pasini D.

PLoS One. 2008 Jul 16;3(7):e2704. doi: 10.1371/journal.pone.0002704.


Polycomb repressive complex 2 in embryonic stem cells: an overview.

Jones A, Wang H.

Protein Cell. 2010 Dec;1(12):1056-62. doi: 10.1007/s13238-010-0142-7. Epub 2011 Jan 8. Review.


Polycomb (PcG) proteins, BMI1 and SUZ12, regulate arsenic-induced cell transformation.

Kim HG, Kim DJ, Li S, Lee KY, Li X, Bode AM, Dong Z.

J Biol Chem. 2012 Sep 14;287(38):31920-8. doi: 10.1074/jbc.M112.360362. Epub 2012 Jul 28.


The gastrointestinal tract stem cell niche.

Yen TH, Wright NA.

Stem Cell Rev. 2006;2(3):203-12. Review.


GATA-1 utilizes Ikaros and polycomb repressive complex 2 to suppress Hes1 and to promote erythropoiesis.

Ross J, Mavoungou L, Bresnick EH, Milot E.

Mol Cell Biol. 2012 Sep;32(18):3624-38. doi: 10.1128/MCB.00163-12. Epub 2012 Jul 9.


Regulation of CD11b transcription by decreasing PRC2 and increased acH4 level during ATRA-induced HL-60 differentiation.

Tang H, Chen F, Tan Q, Tan S, Liu L, Zhang F.

Acta Biochim Biophys Sin (Shanghai). 2009 Jul;41(7):588-93.


A histone mutant reproduces the phenotype caused by loss of histone-modifying factor Polycomb.

Pengelly AR, Copur Ö, Jäckle H, Herzig A, Müller J.

Science. 2013 Feb 8;339(6120):698-9. doi: 10.1126/science.1231382.


Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells.

Benoit YD, Witherspoon MS, Laursen KB, Guezguez A, Beauséjour M, Beaulieu JF, Lipkin SM, Gudas LJ.

Exp Cell Res. 2013 Jun 10;319(10):1463-70. doi: 10.1016/j.yexcr.2013.04.006. Epub 2013 Apr 12.


Cryosectioning the intestinal crypt-villus axis: an ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells.

Vincent A, Kazmierczak C, Duchêne B, Jonckheere N, Leteurtre E, Van Seuningen I.

Stem Cell Res. 2015 Jan;14(1):105-13. doi: 10.1016/j.scr.2014.12.002. Epub 2014 Dec 27.


Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes.

Sher F, Boddeke E, Olah M, Copray S.

PLoS One. 2012;7(7):e40399. doi: 10.1371/journal.pone.0040399. Epub 2012 Jul 12.


Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

Kirmizis A, Bartley SM, Kuzmichev A, Margueron R, Reinberg D, Green R, Farnham PJ.

Genes Dev. 2004 Jul 1;18(13):1592-605.


Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.

Lee SC, Phipson B, Hyland CD, Leong HS, Allan RS, Lun A, Hilton DJ, Nutt SL, Blewitt ME, Smyth GK, Alexander WS, Majewski IJ.

Blood. 2013 Oct 10;122(15):2654-63. doi: 10.1182/blood-2013-02-484055. Epub 2013 Aug 27.


Cooperation between HNF-1alpha, Cdx2, and GATA-4 in initiating an enterocytic differentiation program in a normal human intestinal epithelial progenitor cell line.

Benoit YD, Paré F, Francoeur C, Jean D, Tremblay E, Boudreau F, Escaffit F, Beaulieu JF.

Am J Physiol Gastrointest Liver Physiol. 2010 Apr;298(4):G504-17. doi: 10.1152/ajpgi.00265.2009. Epub 2010 Feb 4.


Ezh2 maintains a key phase of muscle satellite cell expansion but does not regulate terminal differentiation.

Woodhouse S, Pugazhendhi D, Brien P, Pell JM.

J Cell Sci. 2013 Jan 15;126(Pt 2):565-79. doi: 10.1242/jcs.114843. Epub 2012 Nov 30.


Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells.

Neri F, Zippo A, Krepelova A, Cherubini A, Rocchigiani M, Oliviero S.

Mol Cell Biol. 2012 Feb;32(4):840-51. doi: 10.1128/MCB.06148-11. Epub 2011 Dec 19.

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