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Results: 1 to 20 of 133

1.

Mechanical unloading reverses transverse tubule remodelling and normalizes local Ca(2+)-induced Ca(2+)release in a rodent model of heart failure.

Ibrahim M, Navaratnarajah M, Siedlecka U, Rao C, Dias P, Moshkov AV, Gorelik J, Yacoub MH, Terracciano CM.

Eur J Heart Fail. 2012 Jun;14(6):571-80. doi: 10.1093/eurjhf/hfs038. Epub 2012 Apr 1.

PMID:
22467752
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure.

Soppa GK, Lee J, Stagg MA, Felkin LE, Barton PJ, Siedlecka U, Youssef S, Yacoub MH, Terracciano CM.

Cardiovasc Res. 2008 Mar 1;77(4):695-706. doi: 10.1093/cvr/cvm106. Epub 2008 Jan 4. Erratum in: Cardiovasc Res. 2008 Oct 1;80(1):159.

PMID:
18178572
[PubMed - indexed for MEDLINE]
Free Article
3.

Cardiomyocyte Ca2+ handling and structure is regulated by degree and duration of mechanical load variation.

Ibrahim M, Kukadia P, Siedlecka U, Cartledge JE, Navaratnarajah M, Tokar S, Van Doorn C, Tsang VT, Gorelik J, Yacoub MH, Terracciano CM.

J Cell Mol Med. 2012 Dec;16(12):2910-8. doi: 10.1111/j.1582-4934.2012.01611.x.

PMID:
22862818
[PubMed - indexed for MEDLINE]
4.

Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface.

Ibrahim M, Al Masri A, Navaratnarajah M, Siedlecka U, Soppa GK, Moshkov A, Al-Saud SA, Gorelik J, Yacoub MH, Terracciano CM.

FASEB J. 2010 Sep;24(9):3321-9. doi: 10.1096/fj.10-156638. Epub 2010 Apr 29.

PMID:
20430793
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Prolonged mechanical unloading reduces myofilament sensitivity to calcium and sarcoplasmic reticulum calcium uptake leading to contractile dysfunction.

Soppa GK, Lee J, Stagg MA, Siedlecka U, Youssef S, Yacoub MH, Terracciano CM.

J Heart Lung Transplant. 2008 Aug;27(8):882-9. doi: 10.1016/j.healun.2008.05.005. Epub 2008 Jun 25.

PMID:
18656802
[PubMed - indexed for MEDLINE]
6.

Partial left ventricular unloading reverses contractile dysfunction and helps recover gene expressions in failing rat hearts.

Wang J, Marui A, Ikeda T, Komeda M.

Interact Cardiovasc Thorac Surg. 2008 Feb;7(1):27-31. Epub 2007 Nov 15.

PMID:
18006556
[PubMed - indexed for MEDLINE]
Free Article
7.

Determination of optimal duration of mechanical unloading for failing hearts to achieve bridge to recovery in a rat heterotopic heart transplantation model.

Oriyanhan W, Tsuneyoshi H, Nishina T, Matsuoka S, Ikeda T, Komeda M.

J Heart Lung Transplant. 2007 Jan;26(1):16-23.

PMID:
17234512
[PubMed - indexed for MEDLINE]
8.

Chronic partial unloading restores beta-adrenergic responsiveness and reverses receptor downregulation in failing rat hearts.

Wang J, Tsukashita M, Nishina T, Marui A, Yoshikawa E, Muranaka H, Matsuoka S, Ikeda T.

J Thorac Cardiovasc Surg. 2009 Feb;137(2):465-70. doi: 10.1016/j.jtcvs.2008.08.033. Epub 2008 Dec 19.

PMID:
19185171
[PubMed - indexed for MEDLINE]
9.

Mechanical unloading improves intracellular Ca2+ regulation in rats with doxorubicin-induced cardiomyopathy.

Takaseya T, Ishimatsu M, Tayama E, Nishi A, Akasu T, Aoyagi S.

J Am Coll Cardiol. 2004 Dec 7;44(11):2239-46.

PMID:
15582323
[PubMed - indexed for MEDLINE]
Free Article
10.

Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart.

Lyon AR, MacLeod KT, Zhang Y, Garcia E, Kanda GK, Lab MJ, Korchev YE, Harding SE, Gorelik J.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6854-9. doi: 10.1073/pnas.0809777106. Epub 2009 Apr 2.

PMID:
19342485
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

[Effect of carvedilol on ryanodine receptor in heart failure].

Li R, Yi QJ, Qian YR, Liu XY.

Zhonghua Er Ke Za Zhi. 2005 Aug;43(8):603-7. Chinese.

PMID:
16191273
[PubMed - indexed for MEDLINE]
12.

Influence of ivabradine on reverse remodelling during mechanical unloading.

Navaratnarajah M, Ibrahim M, Siedlecka U, van Doorn C, Shah A, Gandhi A, Dias P, Sarathchandra P, Yacoub MH, Terracciano CM.

Cardiovasc Res. 2013 Feb 1;97(2):230-9. doi: 10.1093/cvr/cvs318. Epub 2012 Oct 18.

PMID:
23079200
[PubMed - indexed for MEDLINE]
Free Article
13.

T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction.

Louch WE, Mørk HK, Sexton J, Strømme TA, Laake P, Sjaastad I, Sejersted OM.

J Physiol. 2006 Jul 15;574(Pt 2):519-33. Epub 2006 May 18.

PMID:
16709642
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.

Xie YP, Chen B, Sanders P, Guo A, Li Y, Zimmerman K, Wang LC, Weiss RM, Grumbach IM, Anderson ME, Song LS.

Hypertension. 2012 Feb;59(2):355-62. doi: 10.1161/HYPERTENSIONAHA.111.180968. Epub 2011 Dec 27.

PMID:
22203744
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units?

Louch WE, Hake J, Mørk HK, Hougen K, Skrbic B, Ursu D, Tønnessen T, Sjaastad I, Sejersted OM.

J Mol Cell Cardiol. 2013 May;58:41-52. doi: 10.1016/j.yjmcc.2013.01.014. Epub 2013 Jan 30.

PMID:
23376034
[PubMed - indexed for MEDLINE]
16.

Enhanced Ca²+ influx through cardiac L-type Ca²+ channels maintains the systolic Ca²+ transient in early cardiac atrophy induced by mechanical unloading.

Schwoerer AP, Neef S, Broichhausen I, Jacubeit J, Tiburcy M, Wagner M, Biermann D, Didié M, Vettel C, Maier LS, Zimmermann WH, Carrier L, Eschenhagen T, Volk T, El-Armouche A, Ehmke H.

Pflugers Arch. 2013 Dec;465(12):1763-73. doi: 10.1007/s00424-013-1316-y. Epub 2013 Jul 11.

PMID:
23842739
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Short-term mechanical unloading with left ventricular assist devices after acute myocardial infarction conserves calcium cycling and improves heart function.

Wei X, Li T, Hagen B, Zhang P, Sanchez PG, Williams K, Li S, Bianchi G, Son HS, Wu C, DeFilippi C, Xu K, Lederer WJ, Wu ZJ, Griffith BP.

JACC Cardiovasc Interv. 2013 Apr;6(4):406-15. doi: 10.1016/j.jcin.2012.12.122. Epub 2013 Mar 20. Erratum in: JACC Cardiovasc Interv. 2013 Sep;6(9):992.

PMID:
23523452
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Heterotopic transplantation of the failing rat heart as a model of left ventricular mechanical unloading toward recovery.

Tsuneyoshi H, Oriyanhan W, Kanemitsu H, Shiina R, Nishina T, Ikeda T, Nishimura K, Komeda M.

ASAIO J. 2005 Jan-Feb;51(1):116-20.

PMID:
15745145
[PubMed - indexed for MEDLINE]
19.

Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart.

Chaudhary KW, Rossman EI, Piacentino V 3rd, Kenessey A, Weber C, Gaughan JP, Ojamaa K, Klein I, Bers DM, Houser SR, Margulies KB.

J Am Coll Cardiol. 2004 Aug 18;44(4):837-45.

PMID:
15312868
[PubMed - indexed for MEDLINE]
Free Article
20.

A critical role for Telethonin in regulating t-tubule structure and function in the mammalian heart.

Ibrahim M, Siedlecka U, Buyandelger B, Harada M, Rao C, Moshkov A, Bhargava A, Schneider M, Yacoub MH, Gorelik J, Knöll R, Terracciano CM.

Hum Mol Genet. 2013 Jan 15;22(2):372-83. doi: 10.1093/hmg/dds434. Epub 2012 Oct 25.

PMID:
23100327
[PubMed - indexed for MEDLINE]
Free PMC Article

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