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Results: 1 to 20 of 138

1.

Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia.

Mancini M, Veljkovic N, Leo E, Aluigi M, Borsi E, Galloni C, Iacobucci I, Barbieri E, Santucci MA.

J Cell Biochem. 2012 Aug;113(8):2765-74. doi: 10.1002/jcb.24154.

PMID:
22467095
[PubMed - indexed for MEDLINE]
2.

Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds.

Aichberger KJ, Mayerhofer M, Krauth MT, Vales A, Kondo R, Derdak S, Pickl WF, Selzer E, Deininger M, Druker BJ, Sillaber C, Esterbauer H, Valent P.

Cancer Res. 2005 Oct 15;65(20):9436-44.

PMID:
16230407
[PubMed - indexed for MEDLINE]
Free Article
3.

Gadd45a transcriptional induction elicited by the Aurora kinase inhibitor MK-0457 in Bcr-Abl-expressing cells is driven by Oct-1 transcription factor.

Mancini M, Leo E, Aluigi M, Marcozzi C, Borsi E, Barbieri E, Santucci MA.

Leuk Res. 2012 Aug;36(8):1028-34. doi: 10.1016/j.leukres.2012.03.025. Epub 2012 Apr 20.

PMID:
22521726
[PubMed - indexed for MEDLINE]
4.

Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.

Aichberger KJ, Mayerhofer M, Krauth MT, Skvara H, Florian S, Sonneck K, Akgul C, Derdak S, Pickl WF, Wacheck V, Selzer E, Monia BP, Moriggl R, Valent P, Sillaber C.

Blood. 2005 Apr 15;105(8):3303-11. Epub 2004 Dec 30.

PMID:
15626746
[PubMed - indexed for MEDLINE]
Free Article
5.

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW.

Oncogene. 2005 Mar 31;24(14):2317-29.

PMID:
15688014
[PubMed - indexed for MEDLINE]
6.

Decreased TET2 gene expression during chronic myeloid leukemia progression.

Albano F, Anelli L, Zagaria A, Coccaro N, Minervini A, Rossi AR, Specchia G.

Leuk Res. 2011 Nov;35(11):e220-2. doi: 10.1016/j.leukres.2011.07.013. Epub 2011 Jul 27.

PMID:
21794915
[PubMed - indexed for MEDLINE]
7.

Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.

Wagner K, Zhang P, Rosenbauer F, Drescher B, Kobayashi S, Radomska HS, Kutok JL, Gilliland DG, Krauter J, Tenen DG.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6338-43. Epub 2006 Apr 10.

PMID:
16606850
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Imatinib mesylate induces cisplatin hypersensitivity in Bcr-Abl+ cells by differential modulation of p53 transcriptional and proapoptotic activity.

Skorta I, Oren M, Markwardt C, Gutekunst M, Aulitzky WE, van der Kuip H.

Cancer Res. 2009 Dec 15;69(24):9337-45. doi: 10.1158/0008-5472.CAN-09-0548. Epub .

PMID:
19934315
[PubMed - indexed for MEDLINE]
Free Article
9.

Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.

Yasuda T, Shirakata M, Iwama A, Ishii A, Ebihara Y, Osawa M, Honda K, Shinohara H, Sudo K, Tsuji K, Nakauchi H, Iwakura Y, Hirai H, Oda H, Yamamoto T, Yamanashi Y.

J Exp Med. 2004 Dec 20;200(12):1681-7.

PMID:
15611294
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Imatinib (ST1571) provides only limited selectivity for CML cells and treatment might be complicated by silent BCR-ABL genes.

Jiang G, Yang F, Li M, Weissbecker K, Price S, Kim KC, La Russa VF, Safah H, Ehrlich M.

Cancer Biol Ther. 2003 Jan-Feb;2(1):103-8.

PMID:
12673129
[PubMed - indexed for MEDLINE]
Free Article
12.

Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML.

O'Hare T, Pollock R, Stoffregen EP, Keats JA, Abdullah OM, Moseson EM, Rivera VM, Tang H, Metcalf CA 3rd, Bohacek RS, Wang Y, Sundaramoorthi R, Shakespeare WC, Dalgarno D, Clackson T, Sawyer TK, Deininger MW, Druker BJ.

Blood. 2004 Oct 15;104(8):2532-9. Epub 2004 Jul 15.

PMID:
15256422
[PubMed - indexed for MEDLINE]
Free Article
13.

Zinc-finger transcription factor slug contributes to the survival advantage of chronic myeloid leukemia cells.

Mancini M, Petta S, Iacobucci I, Salvestrini V, Barbieri E, Santucci MA.

Cell Signal. 2010 Aug;22(8):1247-53. doi: 10.1016/j.cellsig.2010.04.002. Epub 2010 Apr 11.

PMID:
20388540
[PubMed - indexed for MEDLINE]
14.
15.

P210 Bcr-abl tyrosine kinase interaction with histone deacetylase 1 modifies histone H4 acetylation and chromatin structure of chronic myeloid leukaemia haematopoietic progenitors.

Brusa G, Zuffa E, Mancini M, Benvenuti M, Calonghi N, Barbieri E, Santucci MA.

Br J Haematol. 2006 Feb;132(3):359-69.

PMID:
16409301
[PubMed - indexed for MEDLINE]
16.

A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib.

Mancini M, Corradi V, Petta S, Barbieri E, Manetti F, Botta M, Santucci MA.

J Pharmacol Exp Ther. 2011 Mar;336(3):596-604. doi: 10.1124/jpet.110.172536. Epub 2010 Nov 1.

PMID:
21041536
[PubMed - indexed for MEDLINE]
Free Article
18.

Chibby drives ╬▓ catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1+ cells.

Mancini M, Leo E, Takemaru K, Campi V, Borsi E, Castagnetti F, Gugliotta G, Santucci MA, Martinelli G.

Cell Signal. 2013 Sep;25(9):1820-7. doi: 10.1016/j.cellsig.2013.05.019. Epub 2013 May 24.

PMID:
23707389
[PubMed - indexed for MEDLINE]
Free Article
19.

Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage.

Kusio-Kobialka M, Wolanin K, Podszywalow-Bartnicka P, Sikora E, Skowronek K, McKenna SL, Ghizzoni M, Dekker FJ, Piwocka K.

Apoptosis. 2012 Sep;17(9):950-63. doi: 10.1007/s10495-012-0739-9.

PMID:
22696202
[PubMed - indexed for MEDLINE]
20.

14-3-3 ligand prevents nuclear import of c-ABL protein in chronic myeloid leukemia.

Mancini M, Veljkovic N, Corradi V, Zuffa E, Corrado P, Pagnotta E, Martinelli G, Barbieri E, Santucci MA.

Traffic. 2009 Jun;10(6):637-47. doi: 10.1111/j.1600-0854.2009.00897.x. Epub 2009 Feb 11.

PMID:
19220809
[PubMed - indexed for MEDLINE]

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