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Results: 1 to 20 of 95

1.

Mechanism-based CYP2D6 inactivation by acridone alkaloids of Indonesian medicinal plant Lunasia amara.

Takahashi N, Subehan, Kadota S, Tezuka Y.

Fitoterapia. 2012 Jun;83(4):774-9. doi: 10.1016/j.fitote.2012.03.011. Epub 2012 Mar 17.

PMID:
22465502
[PubMed - indexed for MEDLINE]
2.

Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum.

Subehan, Usia T, Kadota S, Tezuka Y.

Planta Med. 2006 May;72(6):527-32.

PMID:
16808005
[PubMed - indexed for MEDLINE]
3.

Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants.

Subehan, Usia T, Iwata H, Kadota S, Tezuka Y.

J Ethnopharmacol. 2006 May 24;105(3):449-55. Epub 2006 Jan 18.

PMID:
16414224
[PubMed - indexed for MEDLINE]
4.

Cytochrome P450 2D6 (CYP2D6) inhibitory constituents of Catharanthus roseus.

Usia T, Watabe T, Kadota S, Tezuka Y.

Biol Pharm Bull. 2005 Jun;28(6):1021-4.

PMID:
15930738
[PubMed - indexed for MEDLINE]
Free Article
5.

Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.

Song M, Hong M, Lee MY, Jee JG, Lee YM, Bae JS, Jeong TC, Lee S.

Food Chem Toxicol. 2013 Sep;59:549-53. doi: 10.1016/j.fct.2013.06.055. Epub 2013 Jul 5.

PMID:
23835282
[PubMed - indexed for MEDLINE]
6.

The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.

Madeira M, Levine M, Chang TK, Mirfazaelian A, Bellward GD.

Drug Metab Dispos. 2004 Apr;32(4):460-7.

PMID:
16680870
[PubMed - indexed for MEDLINE]
Free Article
7.

The potential for CYP2D6 inhibition screening using a novel scintillation proximity assay-based approach.

Delaporte E, Slaughter DE, Egan MA, Gatto GJ, Santos A, Shelley J, Price E, Howells L, Dean DC, Rodrigues AD.

J Biomol Screen. 2001 Aug;6(4):225-31.

PMID:
11689122
[PubMed - indexed for MEDLINE]
8.

Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: comparison with fluoxetine and quinidine.

Bertelsen KM, Venkatakrishnan K, Von Moltke LL, Obach RS, Greenblatt DJ.

Drug Metab Dispos. 2003 Mar;31(3):289-93.

PMID:
12584155
[PubMed - indexed for MEDLINE]
Free Article
9.

In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.

Pan Y, Abd-Rashid BA, Ismail Z, Ismail R, Mak JW, Pook PC, Er HM, Ong CE.

J Ethnopharmacol. 2010 Jul 20;130(2):275-83. doi: 10.1016/j.jep.2010.05.002. Epub 2010 May 8.

PMID:
20457244
[PubMed - indexed for MEDLINE]
10.

Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.

Al-Jenoobi FI, Al-Thukair AA, Abbas FA, Ansari MJ, Alkharfy KM, Al-Mohizea AM, Al-Suwayeh SA, Jamil S.

Drug Metab Lett. 2010 Jan;4(1):51-5.

PMID:
20201775
[PubMed - indexed for MEDLINE]
11.

CYP3A4 and CYP2D6 inhibitory activities of Indonesian medicinal plants.

Usia T, Iwata H, Hiratsuka A, Watabe T, Kadota S, Tezuka Y.

Phytomedicine. 2006 Jan;13(1-2):67-73. Epub 2005 Jun 29.

PMID:
16360935
[PubMed - indexed for MEDLINE]
12.

Mechanism-based inactivation of CYP2D6 by methylenedioxymethamphetamine.

Heydari A, Yeo KR, Lennard MS, Ellis SW, Tucker GT, Rostami-Hodjegan A.

Drug Metab Dispos. 2004 Nov;32(11):1213-7. Epub 2004 Aug 24.

PMID:
15328252
[PubMed - indexed for MEDLINE]
Free Article
13.

Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.

Schmider J, Greenblatt DJ, Fogelman SM, von Moltke LL, Shader RI.

Biopharm Drug Dispos. 1997 Apr;18(3):227-40.

PMID:
9113345
[PubMed - indexed for MEDLINE]
14.

Bioactive acridone alkaloids from Swinglea glutinosa.

Weniger B, Um BH, Valentin A, Estrada A, Lobstein A, Anton R, Maillé M, Sauvain M.

J Nat Prod. 2001 Sep;64(9):1221-3.

PMID:
11575960
[PubMed - indexed for MEDLINE]
15.

Quinoline alkaloids from Lunasia amara inhibit Mycobacterium tuberculosis H37Rv in vitro.

Aguinaldo AM, Dalangin-Mallari VM, Macabeo AP, Byrne LT, Abe F, Yamauchi T, Franzblau SG.

Int J Antimicrob Agents. 2007 Jun;29(6):744-6. Epub 2007 Mar 30. No abstract available.

PMID:
17399957
[PubMed - indexed for MEDLINE]
16.

The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol.

Hellum BH, Nilsen OG.

Basic Clin Pharmacol Toxicol. 2007 Nov;101(5):350-8.

PMID:
17910620
[PubMed - indexed for MEDLINE]
17.

Mechanism-based inactivation of human liver microsomal CYP3A4 by rutaecarpine and limonin from Evodia fruit extract.

Iwata H, Tezuka Y, Kadota S, Hiratsuka A, Watabe T.

Drug Metab Pharmacokinet. 2005 Feb;20(1):34-45.

PMID:
15770073
[PubMed - indexed for MEDLINE]
Free Article
18.

CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans.

Jacqz-Aigrain E, Funck-Brentano C, Cresteil T.

Pharmacogenetics. 1993 Aug;3(4):197-204.

PMID:
8220439
[PubMed - indexed for MEDLINE]
19.

Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.

Zhou X, Wang Y, Or PM, Wan DC, Kwan YW, Yeung JH.

Phytomedicine. 2012 May 15;19(7):648-57. doi: 10.1016/j.phymed.2012.01.005. Epub 2012 Apr 27.

PMID:
22541637
[PubMed - indexed for MEDLINE]
20.

Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.

Ueng YF, Ko HC, Chen CF, Wang JJ, Chen KT.

Life Sci. 2002 Aug 2;71(11):1267-77.

PMID:
12106592
[PubMed - indexed for MEDLINE]

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