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Results: 1 to 20 of 84

1.

A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function.

Ogata M, Awaji T, Iwasaki N, Fujimaki R, Takizawa M, Maruyama K, Iwamoto Y, Uchigata Y.

Biochem Biophys Res Commun. 2012 Apr 27;421(1):20-6. doi: 10.1016/j.bbrc.2012.03.093. Epub 2012 Mar 23.

PMID:
22465007
[PubMed - indexed for MEDLINE]
2.

Mitochondrial matrix pH controls oxidative phosphorylation and metabolism-secretion coupling in INS-1E clonal beta cells.

Akhmedov D, Braun M, Mataki C, Park KS, Pozzan T, Schoonjans K, Rorsman P, Wollheim CB, Wiederkehr A.

FASEB J. 2010 Nov;24(11):4613-26. doi: 10.1096/fj.10-162222. Epub 2010 Jul 20.

PMID:
20647546
[PubMed - indexed for MEDLINE]
Free Article
3.

Dynamic measurements of mitochondrial hydrogen peroxide concentration and glutathione redox state in rat pancreatic β-cells using ratiometric fluorescent proteins: confounding effects of pH with HyPer but not roGFP1.

Roma LP, Duprez J, Takahashi HK, Gilon P, Wiederkehr A, Jonas JC.

Biochem J. 2012 Feb 1;441(3):971-8. doi: 10.1042/BJ20111770.

PMID:
22050124
[PubMed - indexed for MEDLINE]
Free Article
4.

Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion.

Rutter GA, Theler JM, Murgia M, Wollheim CB, Pozzan T, Rizzuto R.

J Biol Chem. 1993 Oct 25;268(30):22385-90.

PMID:
8226749
[PubMed - indexed for MEDLINE]
Free Article
5.

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion.

Eto K, Tsubamoto Y, Terauchi Y, Sugiyama T, Kishimoto T, Takahashi N, Yamauchi N, Kubota N, Murayama S, Aizawa T, Akanuma Y, Aizawa S, Kasai H, Yazaki Y, Kadowaki T.

Science. 1999 Feb 12;283(5404):981-5.

PMID:
9974390
[PubMed - indexed for MEDLINE]
Free Article
6.

Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas.

Tsuruzoe K, Araki E, Furukawa N, Shirotani T, Matsumoto K, Kaneko K, Motoshima H, Yoshizato K, Shirakami A, Kishikawa H, Miyazaki J, Shichiri M.

Diabetes. 1998 Apr;47(4):621-31.

PMID:
9568696
[PubMed - indexed for MEDLINE]
7.

Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.

Casimir M, Rubi B, Frigerio F, Chaffard G, Maechler P.

Biochem J. 2009 Dec 10;424(3):459-66. doi: 10.1042/BJ20090729.

PMID:
19764902
[PubMed - indexed for MEDLINE]
Free Article
8.

Energetic requirement of insulin secretion distal to calcium influx.

Rustenbeck I, Herrmann C, Grimmsmann T.

Diabetes. 1997 Aug;46(8):1305-11.

PMID:
9231655
[PubMed - indexed for MEDLINE]
9.

Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.

Soejima A, Inoue K, Takai D, Kaneko M, Ishihara H, Oka Y, Hayashi JI.

J Biol Chem. 1996 Oct 18;271(42):26194-9.

PMID:
8824267
[PubMed - indexed for MEDLINE]
Free Article
10.

Effects of high-density lipoproteins on pancreatic beta-cell insulin secretion.

Fryirs MA, Barter PJ, Appavoo M, Tuch BE, Tabet F, Heather AK, Rye KA.

Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1642-8. doi: 10.1161/ATVBAHA.110.207373. Epub 2010 May 13.

PMID:
20466975
[PubMed - indexed for MEDLINE]
Free Article
11.

Pancreatic islet beta-cells transiently metabolize pyruvate.

Rocheleau JV, Head WS, Nicholson WE, Powers AC, Piston DW.

J Biol Chem. 2002 Aug 23;277(34):30914-20. Epub 2002 Jun 17.

PMID:
12070148
[PubMed - indexed for MEDLINE]
Free Article
12.

Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways.

Tuo Y, Wang D, Li S, Chen C.

Endocrine. 2011 Apr;39(2):128-38. doi: 10.1007/s12020-010-9432-3. Epub 2010 Dec 15.

PMID:
21161439
[PubMed - indexed for MEDLINE]
13.

Evidence for vacuolar-type proton pumps in nonmitochondrial and inositol 1,4,5-trisphosphate-sensitive calcium stores of insulin-secreting cells.

Bode H, Himmen A, Göke B.

Pflugers Arch. 1996 May;432(1):97-104.

PMID:
8662273
[PubMed - indexed for MEDLINE]
14.

Secretagogues modulate the calcium concentration in the endoplasmic reticulum of insulin-secreting cells. Studies in aequorin-expressing intact and permeabilized ins-1 cells.

Maechler P, Kennedy ED, Sebö E, Valeva A, Pozzan T, Wollheim CB.

J Biol Chem. 1999 Apr 30;274(18):12583-92.

PMID:
10212237
[PubMed - indexed for MEDLINE]
Free Article
15.

Direct effects of diazoxide on mitochondria in pancreatic B-cells and on isolated liver mitochondria.

Grimmsmann T, Rustenbeck I.

Br J Pharmacol. 1998 Mar;123(5):781-8.

PMID:
9535004
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion.

Rubí B, Ljubicic S, Pournourmohammadi S, Carobbio S, Armanet M, Bartley C, Maechler P.

J Biol Chem. 2005 Nov 4;280(44):36824-32. Epub 2005 Aug 29.

PMID:
16129680
[PubMed - indexed for MEDLINE]
Free Article
18.

The KATP channel is critical for calcium sequestration into non-ER compartments in mouse pancreatic beta cells.

Dufer M, Haspel D, Krippeit-Drews P, Kelm M, Ranta F, Nitschke R, Ullrich S, Aguilar-Bryan L, Bryan J, Drews G.

Cell Physiol Biochem. 2007;20(1-4):65-74.

PMID:
17595516
[PubMed - indexed for MEDLINE]
19.

The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout.

Ravier MA, Eto K, Jonkers FC, Nenquin M, Kadowaki T, Henquin JC.

J Biol Chem. 2000 Jan 21;275(3):1587-93.

PMID:
10636849
[PubMed - indexed for MEDLINE]
Free Article
20.

The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.

Rubi B, del Arco A, Bartley C, Satrustegui J, Maechler P.

J Biol Chem. 2004 Dec 31;279(53):55659-66. Epub 2004 Oct 19.

PMID:
15494407
[PubMed - indexed for MEDLINE]
Free Article

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