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Items: 1 to 20 of 92


Genomics and successful aging: grounds for renewed optimism?

Pilling LC, Harries LW, Powell J, Llewellyn DJ, Ferrucci L, Melzer D.

J Gerontol A Biol Sci Med Sci. 2012 May;67(5):511-9. doi: 10.1093/gerona/gls091. Epub 2012 Mar 27. Review.


Genome-wide association studies: is there a genotype for cognitive decline in older persons with type 2 diabetes?

Abbatecola AM, Olivieri F, Corsonello A, Antonicelli R, Corica F, Lattanzio F.

Curr Pharm Des. 2011;17(4):347-56. Review.


Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P; Genetic and Environmental Risk for Alzheimer's Disease Consortium, Morgan K; Alzheimer's Research UK Consortium.

Neurobiol Aging. 2012 Aug;33(8):1849.e5-18. doi: 10.1016/j.neurobiolaging.2012.02.014. Epub 2012 Mar 23.


Molecular genetics of Alzheimer's disease and aging.

Cacabelos R, Fernandez-Novoa L, Lombardi V, Kubota Y, Takeda M.

Methods Find Exp Clin Pharmacol. 2005 Jul;27 Suppl A:1-573.


Mapping the genetic architecture of gene expression in human liver.

Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R.

PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107.


Genomics of human health and aging.

Kulminski AM, Culminskaya I.

Age (Dordr). 2013 Apr;35(2):455-69. doi: 10.1007/s11357-011-9362-x. Epub 2011 Dec 16.


Models to explore genetics of human aging.

Karasik D, Newman A.

Adv Exp Med Biol. 2015;847:141-61. doi: 10.1007/978-1-4939-2404-2_7. Review.


Genome maintenance and human longevity.

Cho M, Suh Y.

Curr Opin Genet Dev. 2014 Jun;26:105-15. doi: 10.1016/j.gde.2014.07.002. Epub 2014 Aug 28. Review.


Genome-wide allele-specific analysis: insights into regulatory variation.

Pastinen T.

Nat Rev Genet. 2010 Aug;11(8):533-8. doi: 10.1038/nrg2815. Epub 2010 Jun 22. Review.


Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes.

Hale PJ, López-Yunez AM, Chen JY.

BMC Syst Biol. 2012;6 Suppl 3:S16. doi: 10.1186/1752-0509-6-S3-S16. Epub 2012 Dec 17.


Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012).

Foffi G, Pastore A, Piazza F, Temussi PA.

Phys Biol. 2013 Aug 2;10(4):040301. [Epub ahead of print]


On the identification of potential regulatory variants within genome wide association candidate SNP sets.

Chen CY, Chang IS, Hsiung CA, Wasserman WW.

BMC Med Genomics. 2014 Jun 11;7:34. doi: 10.1186/1755-8794-7-34.


Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.

Pendergrass SA, Brown-Gentry K, Dudek S, Frase A, Torstenson ES, Goodloe R, Ambite JL, Avery CL, Buyske S, Bůžková P, Deelman E, Fesinmeyer MD, Haiman CA, Heiss G, Hindorff LA, Hsu CN, Jackson RD, Kooperberg C, Le Marchand L, Lin Y, Matise TC, Monroe KR, Moreland L, Park SL, Reiner A, Wallace R, Wilkens LR, Crawford DC, Ritchie MD.

PLoS Genet. 2013;9(1):e1003087. doi: 10.1371/journal.pgen.1003087. Epub 2013 Jan 31.


Risk-associated coding synonymous SNPs in type 2 diabetes and neurodegenerative diseases: genetic silence and the underrated association with splicing regulation and epigenetics.

Karambataki M, Malousi A, Kouidou S.

Mutat Res. 2014 Dec;770:85-93. doi: 10.1016/j.mrfmmm.2014.09.005. Epub 2014 Sep 27.


Identifying SNP targeted pathways in partial epilepsies with genome-wide association study data.

Bakir-Gungor B, Baykan B, Ugur İseri S, Tuncer FN, Sezerman OU.

Epilepsy Res. 2013 Jul;105(1-2):92-102. doi: 10.1016/j.eplepsyres.2013.02.008. Epub 2013 Mar 14.


Human genetic variations: Beacons on the pathways to successful ageing.

Cluett C, Melzer D.

Mech Ageing Dev. 2009 Sep;130(9):553-63. doi: 10.1016/j.mad.2009.06.009. Epub 2009 Jul 4. Review.


Enrichment Effects on Adult Cognitive Development: Can the Functional Capacity of Older Adults Be Preserved and Enhanced?

Hertzog C, Kramer AF, Wilson RS, Lindenberger U.

Psychol Sci Public Interest. 2008 Oct;9(1):1-65. doi: 10.1111/j.1539-6053.2009.01034.x. Epub 2008 Oct 1.


Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease.

De Ferrari GV, Papassotiropoulos A, Biechele T, Wavrant De-Vrieze F, Avila ME, Major MB, Myers A, Sáez K, Henríquez JP, Zhao A, Wollmer MA, Nitsch RM, Hock C, Morris CM, Hardy J, Moon RT.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9434-9. Epub 2007 May 21.


Genome-wide survey of allele-specific splicing in humans.

Nembaware V, Lupindo B, Schouest K, Spillane C, Scheffler K, Seoighe C.

BMC Genomics. 2008 Jun 2;9:265. doi: 10.1186/1471-2164-9-265.


Genome-wide profiling of blood pressure in adults and children.

Taal HR, Verwoert GC, Demirkan A, Janssens AC, Rice K, Ehret G, Smith AV, Verhaaren BF, Witteman JC, Hofman A, Vernooij MW, Uitterlinden AG, Rivadeneira F, Ikram MA, Levy D, van der Heijden AJ; Cohort for Heart and Aging Research in Genome Epidemiology and Early Genetics and Lifecourse Epidemiology consortia, Jaddoe VW, van Duijn CM.

Hypertension. 2012 Feb;59(2):241-7. doi: 10.1161/HYPERTENSIONAHA.111.179481. Epub 2011 Dec 27.

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