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Items: 1 to 20 of 138


Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.

Chua JJ, Butkevich E, Worseck JM, Kittelmann M, Grønborg M, Behrmann E, Stelzl U, Pavlos NJ, Lalowski MM, Eimer S, Wanker EE, Klopfenstein DR, Jahn R.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5862-7. doi: 10.1073/pnas.1113819109. Epub 2012 Mar 26.


FEZ2 has acquired additional protein interaction partners relative to FEZ1: functional and evolutionary implications.

Alborghetti MR, Furlan AS, Kobarg J.

PLoS One. 2011 Mar 8;6(3):e17426. doi: 10.1371/journal.pone.0017426.


The Caenorhabditis elegans Kinesin-3 motor UNC-104/KIF1A is degraded upon loss of specific binding to cargo.

Kumar J, Choudhary BC, Metpally R, Zheng Q, Nonet ML, Ramanathan S, Klopfenstein DR, Koushika SP.

PLoS Genet. 2010 Nov 4;6(11):e1001200. doi: 10.1371/journal.pgen.1001200.


The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization.

Sakamoto R, Byrd DT, Brown HM, Hisamoto N, Matsumoto K, Jin Y.

Mol Biol Cell. 2005 Feb;16(2):483-96. Epub 2004 Nov 24.


Phosphorylation of Munc18-1 by Dyrk1A regulates its interaction with Syntaxin 1 and X11α.

Park JH, Jung MS, Kim YS, Song WJ, Chung SH.

J Neurochem. 2012 Sep;122(5):1081-91. doi: 10.1111/j.1471-4159.2012.07861.x. Epub 2012 Aug 3.


The Caenorhabditis elegans JIP3 protein UNC-16 functions as an adaptor to link kinesin-1 with cytoplasmic dynein.

Arimoto M, Koushika SP, Choudhary BC, Li C, Matsumoto K, Hisamoto N.

J Neurosci. 2011 Feb 9;31(6):2216-24. doi: 10.1523/JNEUROSCI.2653-10.2011.


Sub-cellular distribution of UNC-104(KIF1A) upon binding to adaptors as UNC-16(JIP3), DNC-1(DCTN1/Glued) and SYD-2(Liprin-α) in C. elegans neurons.

Hsu CC, Moncaleano JD, Wagner OI.

Neuroscience. 2011 Mar 10;176:39-52. doi: 10.1016/j.neuroscience.2010.12.044. Epub 2010 Dec 30.


"JIP"ing along the axon: the complex roles of JIPs in axonal transport.

Koushika SP.

Bioessays. 2008 Jan;30(1):10-4. Review.


Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons.

MacDonald JI, Dietrich A, Gamble S, Hryciw T, Grant RI, Meakin SO.

J Neurochem. 2012 Jun;121(6):861-80. doi: 10.1111/j.1471-4159.2012.07729.x. Epub 2012 Apr 2.


UNC-16, a JNK-signaling scaffold protein, regulates vesicle transport in C. elegans.

Byrd DT, Kawasaki M, Walcoff M, Hisamoto N, Matsumoto K, Jin Y.

Neuron. 2001 Dec 6;32(5):787-800.


Over-expression of GFP-FEZ1 causes generation of multi-lobulated nuclei mediated by microtubules in HEK293 cells.

Lanza DC, Trindade DM, Assmann EM, Kobarg J.

Exp Cell Res. 2008 Jun 10;314(10):2028-39. doi: 10.1016/j.yexcr.2008.02.012. Epub 2008 Mar 4.


UNC-18 modulates ethanol sensitivity in Caenorhabditis elegans.

Graham ME, Edwards MR, Holden-Dye L, Morgan A, Burgoyne RD, Barclay JW.

Mol Biol Cell. 2009 Jan;20(1):43-55. doi: 10.1091/mbc.E08-07-0689. Epub 2008 Oct 15.


Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans.

Wagner OI, Esposito A, Köhler B, Chen CW, Shen CP, Wu GH, Butkevich E, Mandalapu S, Wenzel D, Wouters FS, Klopfenstein DR.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19605-10. doi: 10.1073/pnas.0902949106. Epub 2009 Oct 30.


The kinesin-associated protein UNC-76 is required for axonal transport in the Drosophila nervous system.

Gindhart JG, Chen J, Faulkner M, Gandhi R, Doerner K, Wisniewski T, Nandlestadt A.

Mol Biol Cell. 2003 Aug;14(8):3356-65. Epub 2003 May 3.


Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO).

Alborghetti MR, Furlan Ada S, da Silva JC, Sforça ML, Honorato RV, Granato DC, dos Santos Migueleti DL, Neves JL, de Oliveira PS, Paes-Leme AF, Zeri AC, de Torriani IC, Kobarg J.

PLoS One. 2013 Oct 7;8(10):e76602. doi: 10.1371/journal.pone.0076602. eCollection 2013.


The non-neuronal syntaxin SYN-1 regulates defecation behavior and neural activity in C. elegans through interaction with the Munc13-like protein AEX-1.

Yamashita M, Iwasaki K, Doi M.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):404-8. doi: 10.1016/j.bbrc.2008.11.064. Epub 2008 Nov 24.


Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans.

Johnson JR, Ferdek P, Lian LY, Barclay JW, Burgoyne RD, Morgan A.

Biochem J. 2009 Feb 15;418(1):73-80. doi: 10.1042/BJ20081956.

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