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Results: 1 to 20 of 201

1.

Regulation of NF-κB by ubiquitination and degradation of the IκBs.

Kanarek N, Ben-Neriah Y.

Immunol Rev. 2012 Mar;246(1):77-94. doi: 10.1111/j.1600-065X.2012.01098.x. Review.

PMID:
22435548
[PubMed - indexed for MEDLINE]
2.

Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB.

Spiegelman VS, Stavropoulos P, Latres E, Pagano M, Ronai Z, Slaga TJ, Fuchs SY.

J Biol Chem. 2001 Jul 20;276(29):27152-8. Epub 2001 May 24.

PMID:
11375388
[PubMed - indexed for MEDLINE]
Free Article
3.

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP.

Spencer E, Jiang J, Chen ZJ.

Genes Dev. 1999 Feb 1;13(3):284-94.

PMID:
9990853
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.

Karin M, Ben-Neriah Y.

Annu Rev Immunol. 2000;18:621-63. Review.

PMID:
10837071
[PubMed - indexed for MEDLINE]
5.

Structural studies on 24P-IkappaBalpha peptide derived from a human IkappaB-alpha protein related to the inhibition of the activity of the transcription factor NF-kappaB.

Pons J, Evrard-Todeschi N, Bertho G, Gharbi-Benarous J, Sonois V, Benarous R, Girault JP.

Biochemistry. 2007 Mar 20;46(11):2958-72. Epub 2007 Feb 24.

PMID:
17319651
[PubMed - indexed for MEDLINE]
6.

Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.

Tsuchiya Y, Asano T, Nakayama K, Kato T Jr, Karin M, Kamata H.

Mol Cell. 2010 Aug 27;39(4):570-82. doi: 10.1016/j.molcel.2010.07.030.

PMID:
20797629
[PubMed - indexed for MEDLINE]
Free Article
7.

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase.

Yaron A, Hatzubai A, Davis M, Lavon I, Amit S, Manning AM, Andersen JS, Mann M, Mercurio F, Ben-Neriah Y.

Nature. 1998 Dec 10;396(6711):590-4.

PMID:
9859996
[PubMed - indexed for MEDLINE]
8.

SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4.

Strack P, Caligiuri M, Pelletier M, Boisclair M, Theodoras A, Beer-Romero P, Glass S, Parsons T, Copeland RA, Auger KR, Benfield P, Brizuela L, Rolfe M.

Oncogene. 2000 Jul 20;19(31):3529-36.

PMID:
10918611
[PubMed - indexed for MEDLINE]
Free Article
9.

Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.

Mansur DS, Maluquer de Motes C, Unterholzner L, Sumner RP, Ferguson BJ, Ren H, Strnadova P, Bowie AG, Smith GL.

PLoS Pathog. 2013 Feb;9(2):e1003183. doi: 10.1371/journal.ppat.1003183. Epub 2013 Feb 28.

PMID:
23468625
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Enhanced heat shock protein 70 expression alters proteasomal degradation of IkappaB kinase in experimental acute respiratory distress syndrome.

Weiss YG, Bromberg Z, Raj N, Raphael J, Goloubinoff P, Ben-Neriah Y, Deutschman CS.

Crit Care Med. 2007 Sep;35(9):2128-38.

PMID:
17855826
[PubMed - indexed for MEDLINE]
11.

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

Bour S, Perrin C, Akari H, Strebel K.

J Biol Chem. 2001 May 11;276(19):15920-8. Epub 2001 Feb 16.

PMID:
11278695
[PubMed - indexed for MEDLINE]
Free Article
12.

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro.

Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW.

Genes Dev. 1999 Feb 1;13(3):270-83. Erratum in: Genes Dev 1999 Apr 15;13(8):1050.

PMID:
9990852
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The role of [beta]-transducin repeat-containing protein ([beta]-TrCP) in the regulation of NF-[kappa]B in vascular smooth muscle cells.

Wang X, Adhikari N, Li Q, Guan Z, Hall JL.

Arterioscler Thromb Vasc Biol. 2004 Jan;24(1):85-90. Epub 2003 Oct 30.

PMID:
14592850
[PubMed - indexed for MEDLINE]
Free Article
14.

Associations among beta-TrCP, an E3 ubiquitin ligase receptor, beta-catenin, and NF-kappaB in colorectal cancer.

Ougolkov A, Zhang B, Yamashita K, Bilim V, Mai M, Fuchs SY, Minamoto T.

J Natl Cancer Inst. 2004 Aug 4;96(15):1161-70.

PMID:
15292388
[PubMed - indexed for MEDLINE]
Free Article
15.

beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta.

Wu C, Ghosh S.

J Biol Chem. 1999 Oct 15;274(42):29591-4.

PMID:
10514424
[PubMed - indexed for MEDLINE]
Free Article
16.

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

Fuchs SY, Chen A, Xiong Y, Pan ZQ, Ronai Z.

Oncogene. 1999 Mar 25;18(12):2039-46.

PMID:
10321728
[PubMed - indexed for MEDLINE]
Free Article
17.

Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP.

Morelli M, Dennis AF, Patton JT.

MBio. 2015 Jan 27;6(1). pii: e02490-14. doi: 10.1128/mBio.02490-14.

PMID:
25626907
[PubMed - in process]
Free PMC Article
18.

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha.

Heissmeyer V, Krappmann D, Hatada EN, Scheidereit C.

Mol Cell Biol. 2001 Feb;21(4):1024-35.

PMID:
11158290
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha.

Read MA, Brownell JE, Gladysheva TB, Hottelet M, Parent LA, Coggins MB, Pierce JW, Podust VN, Luo RS, Chau V, Palombella VJ.

Mol Cell Biol. 2000 Apr;20(7):2326-33.

PMID:
10713156
[PubMed - indexed for MEDLINE]
Free PMC Article
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