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Results: 1 to 20 of 212

1.

Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients.

Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Britschgi M, Akatsu H, Hossain MM, Nishitsuji K, van Kuppevelt TH, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K.

Am J Pathol. 2012 May;180(5):2056-67. doi: 10.1016/j.ajpath.2012.01.015. Epub 2012 Mar 17.

PMID:
22429964
[PubMed - indexed for MEDLINE]
2.

Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells.

O'Callaghan P, Sandwall E, Li JP, Yu H, Ravid R, Guan ZZ, van Kuppevelt TH, Nilsson LN, Ingelsson M, Hyman BT, Kalimo H, Lindahl U, Lannfelt L, Zhang X.

Brain Pathol. 2008 Oct;18(4):548-61. doi: 10.1111/j.1750-3639.2008.00152.x. Epub 2008 Apr 11.

PMID:
18422760
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Heparan sulfate proteoglycan in diffuse plaques of hippocampus but not of cerebellum in Alzheimer's disease brain.

Snow AD, Sekiguchi RT, Nochlin D, Kalaria RN, Kimata K.

Am J Pathol. 1994 Feb;144(2):337-47.

PMID:
8311117
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Sulfation of heparan sulfate associated with amyloid-beta plaques in patients with Alzheimer's disease.

Bruinsma IB, te Riet L, Gevers T, ten Dam GB, van Kuppevelt TH, David G, Küsters B, de Waal RM, Verbeek MM.

Acta Neuropathol. 2010 Feb;119(2):211-20. doi: 10.1007/s00401-009-0577-1. Epub 2009 Jul 28.

PMID:
19636575
[PubMed - indexed for MEDLINE]
5.

Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome.

Snow AD, Mar H, Nochlin D, Sekiguchi RT, Kimata K, Koike Y, Wight TN.

Am J Pathol. 1990 Nov;137(5):1253-70.

PMID:
2146882
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease.

Mori T, Koyama N, Arendash GW, Horikoshi-Sakuraba Y, Tan J, Town T.

Glia. 2010 Feb;58(3):300-14. doi: 10.1002/glia.20924.

PMID:
19705461
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease.

Kim WS, Li H, Ruberu K, Chan S, Elliott DA, Low JK, Cheng D, Karl T, Garner B.

J Neurosci. 2013 Mar 6;33(10):4387-94. doi: 10.1523/JNEUROSCI.4165-12.2013.

PMID:
23467355
[PubMed - indexed for MEDLINE]
Free Article
8.

Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.

Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM.

FASEB J. 2005 Dec;19(14):2081-2. Epub 2005 Sep 26.

PMID:
16186174
[PubMed - indexed for MEDLINE]
Free Article
9.

RB4CD12 epitope expression and heparan sulfate disaccharide composition in brain vasculature.

Hosono-Fukao T, Ohtake-Niimi S, Nishitsuji K, Hossain MM, van Kuppevelt TH, Michikawa M, Uchimura K.

J Neurosci Res. 2011 Nov;89(11):1840-8. doi: 10.1002/jnr.22690. Epub 2011 Jul 29.

PMID:
21805491
[PubMed - indexed for MEDLINE]
10.

Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88.

Hossain MM, Hosono-Fukao T, Tang R, Sugaya N, van Kuppevelt TH, Jenniskens GJ, Kimata K, Rosen SD, Uchimura K.

Glycobiology. 2010 Feb;20(2):175-86. doi: 10.1093/glycob/cwp159. Epub 2009 Oct 12.

PMID:
19822709
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Glypican-1 as an Abeta binding HSPG in the human brain: its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease.

Watanabe N, Araki W, Chui DH, Makifuchi T, Ihara Y, Tabira T.

FASEB J. 2004 Jun;18(9):1013-5. Epub 2004 Apr 14.

PMID:
15084524
[PubMed - indexed for MEDLINE]
Free Article
12.

Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.

Pereson S, Wils H, Kleinberger G, McGowan E, Vandewoestyne M, Van Broeck B, Joris G, Cuijt I, Deforce D, Hutton M, Van Broeckhoven C, Kumar-Singh S.

J Pathol. 2009 Oct;219(2):173-81. doi: 10.1002/path.2580.

PMID:
19557827
[PubMed - indexed for MEDLINE]
13.

Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice.

Wiley JC, Pettan-Brewer C, Ladiges WC.

Aging Cell. 2011 Jun;10(3):418-28. doi: 10.1111/j.1474-9726.2011.00680.x. Epub 2011 Mar 22.

PMID:
21272191
[PubMed - indexed for MEDLINE]
14.

Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease.

Chuang JY, Lee CW, Shih YH, Yang T, Yu L, Kuo YM.

PLoS One. 2012;7(3):e33120. doi: 10.1371/journal.pone.0033120. Epub 2012 Mar 6.

PMID:
22412990
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Role of hippocalcin in mediating Aβ toxicity.

Lim YA, Giese M, Shepherd C, Halliday G, Kobayashi M, Takamatsu K, Staufenbiel M, Eckert A, Götz J.

Biochim Biophys Acta. 2012 Aug;1822(8):1247-57. doi: 10.1016/j.bbadis.2012.04.007. Epub 2012 Apr 20.

PMID:
22542901
[PubMed - indexed for MEDLINE]
Free Article
16.

Correlation of Aβ deposition in the nasal cavity with the formation of senile plaques in the brain of a transgenic mouse model of Alzheimer's disease.

Kameshima N, Nanjou T, Fukuhara T, Yanagisawa D, Tooyama I.

Neurosci Lett. 2012 Apr 4;513(2):166-9. doi: 10.1016/j.neulet.2012.02.026. Epub 2012 Feb 17.

PMID:
22343315
[PubMed - indexed for MEDLINE]
17.

Increased β-amyloid deposition in Tg-SWDI transgenic mouse brain following in vivo lead exposure.

Gu H, Robison G, Hong L, Barrea R, Wei X, Farlow MR, Pushkar YN, Du Y, Zheng W.

Toxicol Lett. 2012 Sep 3;213(2):211-9. doi: 10.1016/j.toxlet.2012.07.002. Epub 2012 Jul 11.

PMID:
22796588
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease.

Su JH, Cummings BJ, Cotman CW.

Neuroscience. 1992 Dec;51(4):801-13.

PMID:
1488123
[PubMed - indexed for MEDLINE]
19.

RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.

Cho HJ, Son SM, Jin SM, Hong HS, Shin DH, Kim SJ, Huh K, Mook-Jung I.

FASEB J. 2009 Aug;23(8):2639-49. doi: 10.1096/fj.08-126383. Epub 2009 Mar 30.

PMID:
19332646
[PubMed - indexed for MEDLINE]
Free Article
20.

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG.

J Neurosci. 2001 Jan 15;21(2):372-81.

PMID:
11160418
[PubMed - indexed for MEDLINE]
Free Article

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