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Items: 1 to 20 of 100

1.

Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis.

Leroux A, Ferrere G, Godie V, Cailleux F, Renoud ML, Gaudin F, Naveau S, Prévot S, Makhzami S, Perlemuter G, Cassard-Doulcier AM.

J Hepatol. 2012 Jul;57(1):141-9. doi: 10.1016/j.jhep.2012.02.028. Epub 2012 Mar 14.

PMID:
22425624
2.

Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice.

Hoo RL, Lee IP, Zhou M, Wong JY, Hui X, Xu A, Lam KS.

J Hepatol. 2013 Feb;58(2):358-64. doi: 10.1016/j.jhep.2012.10.022. Epub 2012 Oct 26.

PMID:
23108115
3.

Obesity-induced lymphocyte hyperresponsiveness to chemokines: a new mechanism of Fatty liver inflammation in obese mice.

Bigorgne AE, Bouchet-Delbos L, Naveau S, Dagher I, Prévot S, Durand-Gasselin I, Couderc J, Valet P, Emilie D, Perlemuter G.

Gastroenterology. 2008 May;134(5):1459-69. doi: 10.1053/j.gastro.2008.02.055. Epub 2008 Mar 4.

PMID:
18471520
4.

Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models.

Miyashita T, Toyoda Y, Tsuneyama K, Fukami T, Nakajima M, Yokoi T.

J Toxicol Sci. 2012;37(5):931-42.

5.

PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes.

Schadinger SE, Bucher NL, Schreiber BM, Farmer SR.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1195-205. Epub 2005 Jan 11.

6.

Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice.

Larter CZ, Yeh MM, Van Rooyen DM, Teoh NC, Brooling J, Hou JY, Williams J, Clyne M, Nolan CJ, Farrell GC.

J Gastroenterol Hepatol. 2009 Oct;24(10):1658-68. doi: 10.1111/j.1440-1746.2009.05996.x.

PMID:
19788606
7.

Possible involvement and the mechanisms of excess trans-fatty acid consumption in severe NAFLD in mice.

Obara N, Fukushima K, Ueno Y, Wakui Y, Kimura O, Tamai K, Kakazu E, Inoue J, Kondo Y, Ogawa N, Sato K, Tsuduki T, Ishida K, Shimosegawa T.

J Hepatol. 2010 Aug;53(2):326-34. doi: 10.1016/j.jhep.2010.02.029. Epub 2010 Apr 22.

PMID:
20462650
8.

Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways.

Larter CZ, Yeh MM, Haigh WG, Williams J, Brown S, Bell-Anderson KS, Lee SP, Farrell GC.

J Hepatol. 2008 Apr;48(4):638-47. doi: 10.1016/j.jhep.2007.12.011. Epub 2008 Jan 28.

PMID:
18280001
9.

[An experimental study on the reverse mechanism of PPAR-gamma agonist rosiglitazone in rats with non-alcoholic steatohepatitis].

Zhao CY, Wang YD, Zhou JY, Jia B, Cui JF.

Zhonghua Gan Zang Bing Za Zhi. 2007 Jun;15(6):450-5. Chinese.

PMID:
17594812
10.

Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death.

Tang T, Sui Y, Lian M, Li Z, Hua J.

PLoS One. 2013 Dec 3;8(12):e81949. doi: 10.1371/journal.pone.0081949. eCollection 2013.

11.

Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state.

Hall D, Poussin C, Velagapudi VR, Empsen C, Joffraud M, Beckmann JS, Geerts AE, Ravussin Y, Ibberson M, Oresic M, Thorens B.

J Biol Chem. 2010 Oct 1;285(40):31011-23. doi: 10.1074/jbc.M110.127159. Epub 2010 Jul 6.

12.

Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice.

Ye D, Li FY, Lam KS, Li H, Jia W, Wang Y, Man K, Lo CM, Li X, Xu A.

Gut. 2012 Jul;61(7):1058-67. doi: 10.1136/gutjnl-2011-300269. Epub 2012 Jan 17.

PMID:
22253482
13.

Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates.

Shiri-Sverdlov R, Wouters K, van Gorp PJ, Gijbels MJ, Noel B, Buffat L, Staels B, Maeda N, van Bilsen M, Hofker MH.

J Hepatol. 2006 Apr;44(4):732-41. Epub 2005 Dec 20.

PMID:
16466828
14.

Preventative effects of Platycodon grandiflorum treatment on hepatic steatosis in high fat diet-fed C57BL/6 mice.

Noh JR, Kim YH, Gang GT, Yang KJ, Kim SK, Ryu SY, Kim YS, Lee CH, Lee HS.

Biol Pharm Bull. 2010;33(3):450-4.

15.

Effect of high fat diet on the volume of liver and quantitative feature of Kupffer cells in the female rat: a stereological and ultrastructural study.

Kiki I, Altunkaynak BZ, Altunkaynak ME, Vuraler O, Unal D, Kaplan S.

Obes Surg. 2007 Oct;17(10):1381-8.

PMID:
18000736
16.

Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.

Nagasawa T, Inada Y, Nakano S, Tamura T, Takahashi T, Maruyama K, Yamazaki Y, Kuroda J, Shibata N.

Eur J Pharmacol. 2006 Apr 24;536(1-2):182-91. Epub 2006 Feb 28.

PMID:
16574099
17.

Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis.

Monsénégo J, Mansouri A, Akkaoui M, Lenoir V, Esnous C, Fauveau V, Tavernier V, Girard J, Prip-Buus C.

J Hepatol. 2012 Mar;56(3):632-9. doi: 10.1016/j.jhep.2011.10.008. Epub 2011 Oct 25.

PMID:
22037024
18.

Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system.

Li Z, Lin H, Yang S, Diehl AM.

Gastroenterology. 2002 Oct;123(4):1304-10.

PMID:
12360490
19.

CD14 expression and Kupffer cell dysfunction in non-alcoholic steatohepatitis: superparamagnetic iron oxide-magnetic resonance image and pathologic correlation.

Tonan T, Fujimoto K, Qayyum A, Morita Y, Nakashima O, Ono N, Kawahara A, Kage M, Hayabuchi N, Ueno T.

J Gastroenterol Hepatol. 2012 Apr;27(4):789-96. doi: 10.1111/j.1440-1746.2011.07057.x.

PMID:
22188204
20.

Kupffer cell activation is a causal factor for hepatic insulin resistance.

Lanthier N, Molendi-Coste O, Horsmans Y, van Rooijen N, Cani PD, Leclercq IA.

Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G107-16. doi: 10.1152/ajpgi.00391.2009. Epub 2009 Oct 29.

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