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Items: 1 to 20 of 243

1.

L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice.

Hoshi M, Matsumoto K, Ito H, Ohtaki H, Arioka Y, Osawa Y, Yamamoto Y, Matsunami H, Hara A, Seishima M, Saito K.

J Immunol. 2012 Apr 15;188(8):3980-7. doi: 10.4049/jimmunol.1100997. Epub 2012 Mar 14.

2.

The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse.

Hoshi M, Saito K, Hara A, Taguchi A, Ohtaki H, Tanaka R, Fujigaki H, Osawa Y, Takemura M, Matsunami H, Ito H, Seishima M.

J Immunol. 2010 Sep 15;185(6):3305-12. doi: 10.4049/jimmunol.0901150. Epub 2010 Aug 6.

3.

Increased serum kynurenine/tryptophan ratio correlates with disease progression in lung cancer.

Suzuki Y, Suda T, Furuhashi K, Suzuki M, Fujie M, Hahimoto D, Nakamura Y, Inui N, Nakamura H, Chida K.

Lung Cancer. 2010 Mar;67(3):361-5. doi: 10.1016/j.lungcan.2009.05.001. Epub 2009 May 31.

PMID:
19487045
5.

Flavivirus infection induces indoleamine 2,3-dioxygenase in human monocyte-derived macrophages via tumor necrosis factor and NF-κB.

Yeung AW, Wu W, Freewan M, Stocker R, King NJ, Thomas SR.

J Leukoc Biol. 2012 Apr;91(4):657-66. doi: 10.1189/jlb.1011532. Epub 2012 Feb 1.

PMID:
22301793
6.

Serum tryptophan and kynurenine concentrations as parameters for indoleamine 2,3-dioxygenase activity in patients with endometrial, ovarian, and vulvar cancer.

de Jong RA, Nijman HW, Boezen HM, Volmer M, Ten Hoor KA, Krijnen J, van der Zee AG, Hollema H, Kema IP.

Int J Gynecol Cancer. 2011 Oct;21(7):1320-7. doi: 10.1097/IGC.0b013e31822017fb.

PMID:
21720257
7.

Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.

Jackman KA, Brait VH, Wang Y, Maghzal GJ, Ball HJ, McKenzie G, De Silva TM, Stocker R, Sobey CG.

Naunyn Schmiedebergs Arch Pharmacol. 2011 May;383(5):471-81. doi: 10.1007/s00210-011-0611-4. Epub 2011 Feb 27.

PMID:
21359968
8.

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.

Schefold JC, Zeden JP, Fotopoulou C, von Haehling S, Pschowski R, Hasper D, Volk HD, Schuett C, Reinke P.

Nephrol Dial Transplant. 2009 Jun;24(6):1901-8. doi: 10.1093/ndt/gfn739. Epub 2009 Jan 20.

9.

IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity.

Wichers MC, Koek GH, Robaeys G, Verkerk R, Scharpé S, Maes M.

Mol Psychiatry. 2005 Jun;10(6):538-44.

PMID:
15494706
10.

Serum activity of indoleamine 2,3-dioxygenase predicts prognosis of community-acquired pneumonia.

Suzuki Y, Suda T, Yokomura K, Suzuki M, Fujie M, Furuhashi K, Hahimoto D, Enomto N, Fujisawa T, Nakamura Y, Inui N, Nakano Y, Nakamura H, Chida K.

J Infect. 2011 Sep;63(3):215-22. doi: 10.1016/j.jinf.2011.07.003. Epub 2011 Jul 19.

PMID:
21784100
11.

Implications of interferon-induced tryptophan catabolism in cancer, auto-immune diseases and AIDS.

Brown RR, Ozaki Y, Datta SP, Borden EC, Sondel PM, Malone DG.

Adv Exp Med Biol. 1991;294:425-35. Review.

PMID:
1722946
12.

Mechanisms dependent on tryptophan catabolism regulate immune responses in primary Sjögren's syndrome.

Pertovaara M, Raitala A, Uusitalo H, Pukander J, Helin H, Oja SS, Hurme M.

Clin Exp Immunol. 2005 Oct;142(1):155-61.

13.

High-affinity uptake of kynurenine and nitric oxide-mediated inhibition of indoleamine 2,3-dioxygenase in bone marrow-derived myeloid dendritic cells.

Hara T, Ogasawara N, Akimoto H, Takikawa O, Hiramatsu R, Kawabe T, Isobe K, Nagase F.

Immunol Lett. 2008 Feb 15;116(1):95-102. doi: 10.1016/j.imlet.2007.11.016. Epub 2007 Dec 26.

PMID:
18179826
14.

Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase.

Rytelewski M, Meilleur CE, Yekta MA, Szabo PA, Garg N, Schell TD, Jevnikar AM, Sharif S, Singh B, Haeryfar SM.

PLoS One. 2014 Feb 28;9(2):e90439. doi: 10.1371/journal.pone.0090439. eCollection 2014.

15.

Tryptophan degradation in multiple trauma patients: survivors compared with non-survivors.

Ploder M, Spittler A, Schroecksnadel K, Neurauter G, Pelinka LE, Roth E, Fuchs D.

Clin Sci (Lond). 2009 Apr;116(7):593-8. doi: 10.1042/CS20080319.

PMID:
18986303
16.

Cell cycle arrest by kynurenine in lens epithelial cells.

Mailankot M, Smith D, Howell S, Wang B, Jacobberger JW, Stefan T, Nagaraj RH.

Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5466-75. doi: 10.1167/iovs.08-2374. Epub 2008 Aug 1.

17.

Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation.

Brandacher G, Cakar F, Winkler C, Schneeberger S, Obrist P, Bösmüller C, Werner-Felmayer G, Werner ER, Bonatti H, Margreiter R, Fuchs D.

Kidney Int. 2007 Jan;71(1):60-7. Epub 2006 Nov 15.

19.

Malaria parasite induces tryptophan-related immune suppression in mice.

Tetsutani K, To H, Torii M, Hisaeda H, Himeno K.

Parasitology. 2007 Jul;134(Pt 7):923-30. Epub 2007 Feb 22.

PMID:
17316473
20.
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