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Items: 1 to 20 of 108

1.

Notch inhibition as a promising new approach to cancer therapy.

Purow B.

Adv Exp Med Biol. 2012;727:305-19. doi: 10.1007/978-1-4614-0899-4_23. Review.

2.

Notch inhibitors as a new tool in the war on cancer: a pathway to watch.

Purow B.

Curr Pharm Biotechnol. 2009 Feb;10(2):154-60. Review.

3.

Notch inhibitors for cancer treatment.

Espinoza I, Miele L.

Pharmacol Ther. 2013 Aug;139(2):95-110. doi: 10.1016/j.pharmthera.2013.02.003. Epub 2013 Feb 28. Review.

4.

Notch signaling in cancer.

Miele L, Golde T, Osborne B.

Curr Mol Med. 2006 Dec;6(8):905-18. Review.

PMID:
17168741
5.

Notch signaling: an emerging therapeutic target for cancer treatment.

Yuan X, Wu H, Xu H, Xiong H, Chu Q, Yu S, Wu GS, Wu K.

Cancer Lett. 2015 Dec 1;369(1):20-7. doi: 10.1016/j.canlet.2015.07.048. Epub 2015 Sep 1. Review.

6.

NOTCH signaling as a novel cancer therapeutic target.

Miele L, Miao H, Nickoloff BJ.

Curr Cancer Drug Targets. 2006 Jun;6(4):313-23. Review.

PMID:
16848722
7.

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways.

Takebe N, Harris PJ, Warren RQ, Ivy SP.

Nat Rev Clin Oncol. 2011 Feb;8(2):97-106. doi: 10.1038/nrclinonc.2010.196. Epub 2010 Dec 14. Review.

PMID:
21151206
8.

Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.

Groth C, Fortini ME.

Semin Cell Dev Biol. 2012 Jun;23(4):465-72. doi: 10.1016/j.semcdb.2012.01.016. Epub 2012 Jan 30. Review.

9.

Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials.

Shi W, Harris AL.

J Mammary Gland Biol Neoplasia. 2006 Jan;11(1):41-52. Review.

PMID:
16947085
10.

Therapeutic antibody targeting of individual Notch receptors.

Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW.

Nature. 2010 Apr 15;464(7291):1052-7. doi: 10.1038/nature08878.

PMID:
20393564
11.

Targeting notch signaling pathway in cancer: clinical development advances and challenges.

Takebe N, Nguyen D, Yang SX.

Pharmacol Ther. 2014 Feb;141(2):140-9. doi: 10.1016/j.pharmthera.2013.09.005. Epub 2013 Sep 27. Review.

12.

Regulation of EMT by Notch signaling pathway in tumor progression.

Li Y, Ma J, Qian X, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z.

Curr Cancer Drug Targets. 2013 Nov;13(9):957-62. Review.

PMID:
24168187
13.

Notch signaling: emerging molecular targets for cancer therapy.

Yin L, Velazquez OC, Liu ZJ.

Biochem Pharmacol. 2010 Sep 1;80(5):690-701. doi: 10.1016/j.bcp.2010.03.026. Epub 2010 Mar 31. Review.

PMID:
20361945
14.

Notch regulation of tumor angiogenesis.

Bridges E, Oon CE, Harris A.

Future Oncol. 2011 Apr;7(4):569-88. doi: 10.2217/fon.11.20. Review.

PMID:
21463145
15.

Role of Notch signalling pathway in cancer and its association with DNA methylation.

Aithal MG, Rajeswari N.

J Genet. 2013 Dec;92(3):667-75. Review.

16.

Mechanisms and clinical prospects of Notch inhibitors in the therapy of hematological malignancies.

Nefedova Y, Gabrilovich D.

Drug Resist Updat. 2008 Dec;11(6):210-8. doi: 10.1016/j.drup.2008.09.002. Epub 2008 Oct 31. Review.

17.

Targeting notch to eradicate pancreatic cancer stem cells for cancer therapy.

Wang Z, Ahmad A, Li Y, Azmi AS, Miele L, Sarkar FH.

Anticancer Res. 2011 Apr;31(4):1105-13. Review.

PMID:
21508353
18.

Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer.

Mamaeva V, Rosenholm JM, Bate-Eya LT, Bergman L, Peuhu E, Duchanoy A, Fortelius LE, Landor S, Toivola DM, Lindén M, Sahlgren C.

Mol Ther. 2011 Aug;19(8):1538-46. doi: 10.1038/mt.2011.105. Epub 2011 May 31.

19.

Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer.

Dong Y, Li A, Wang J, Weber JD, Michel LS.

Cancer Res. 2010 Jul 1;70(13):5465-74. doi: 10.1158/0008-5472.CAN-10-0173. Epub 2010 Jun 22.

20.

Rational targeting of Notch signaling in cancer.

Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L.

Oncogene. 2008 Sep 1;27(38):5124-31. doi: 10.1038/onc.2008.226. Review.

PMID:
18758481
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