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Items: 1 to 20 of 124

1.

Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death.

Fu AK, Hung KW, Wong HH, Fu WY, Ip NY.

Neurosignals. 2013;21(1-2):55-60. doi: 10.1159/000335158. Epub 2012 Mar 6.

PMID:
22398430
2.

Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription.

Li Z, David G, Hung KW, DePinho RA, Fu AK, Ip NY.

J Biol Chem. 2004 Dec 24;279(52):54438-44. Epub 2004 Oct 15.

3.

Cdk5 interacts with Hif-1α in neurons: a new hypoxic signalling mechanism?

Antoniou X, Gassmann M, Ogunshola OO.

Brain Res. 2011 Mar 24;1381:1-10. doi: 10.1016/j.brainres.2010.10.071. Epub 2010 Oct 25.

PMID:
20977891
4.

p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide.

Seyb KI, Ansar S, Li G, Bean J, Michaelis ML, Dobrowsky RT.

J Mol Neurosci. 2007;31(1):23-35.

PMID:
17416967
5.

Histone acetylation and the cell-cycle in cancer.

Wang C, Fu M, Mani S, Wadler S, Senderowicz AM, Pestell RG.

Front Biosci. 2001 Apr 1;6:D610-29. Review.

PMID:
11282573
6.

Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death.

Lee JH, Kim HS, Lee SJ, Kim KT.

J Cell Sci. 2007 Jul 1;120(Pt 13):2259-71.

7.

Regulation and role of cyclin-dependent kinase activity in neuronal survival and death.

Hisanaga S, Endo R.

J Neurochem. 2010 Dec;115(6):1309-21. doi: 10.1111/j.1471-4159.2010.07050.x. Epub 2010 Nov 4. Review.

8.

Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3.

Li BS, Zhang L, Takahashi S, Ma W, Jaffe H, Kulkarni AB, Pant HC.

EMBO J. 2002 Feb 1;21(3):324-33.

10.

Cyclin e1 regulates Kv2.1 channel phosphorylation and localization in neuronal ischemia.

Shah NH, Schulien AJ, Clemens K, Aizenman TD, Hageman TM, Wills ZP, Aizenman E.

J Neurosci. 2014 Mar 19;34(12):4326-31. doi: 10.1523/JNEUROSCI.5184-13.2014.

11.

Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration.

Song C, Kanthasamy A, Jin H, Anantharam V, Kanthasamy AG.

Neurotoxicology. 2011 Oct;32(5):586-95. doi: 10.1016/j.neuro.2011.05.018. Epub 2011 Jul 12.

12.

Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2.

Tang X, Wang X, Gong X, Tong M, Park D, Xia Z, Mao Z.

J Neurosci. 2005 May 11;25(19):4823-34.

13.

The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology.

Maccioni RB, Otth C, Concha II, Muñoz JP.

Eur J Biochem. 2001 Mar;268(6):1518-27. Review.

14.

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death.

O'Hare MJ, Kushwaha N, Zhang Y, Aleyasin H, Callaghan SM, Slack RS, Albert PR, Vincent I, Park DS.

J Neurosci. 2005 Sep 28;25(39):8954-66.

15.

Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells.

Sharma R, Ottenhof T, Rzeczkowska PA, Niles LP.

J Pineal Res. 2008 Oct;45(3):277-84. doi: 10.1111/j.1600-079X.2008.00587.x. Epub 2008 Mar 26.

PMID:
18373554
16.

Tyrosine hydroxylase expression and Cdk5 kinase activity in ataxic cerebellum.

Cheung KJ Jr, Rosales JL, Lee BC, Jeong YG, Lee KY.

Mol Cell Biochem. 2008 Nov;318(1-2):7-12. doi: 10.1007/s11010-008-9850-1. Epub 2008 Jul 10.

17.

Phosphorylation of p35 and p39 by Cdk5 determines the subcellular location of the holokinase in a phosphorylation-site-specific manner.

Asada A, Saito T, Hisanaga S.

J Cell Sci. 2012 Jul 15;125(Pt 14):3421-9. doi: 10.1242/jcs.100503. Epub 2012 Mar 30.

18.

Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons.

Futatsugi A, Utreras E, Rudrabhatla P, Jaffe H, Pant HC, Kulkarni AB.

Cell Cycle. 2012 Apr 15;11(8):1603-10. doi: 10.4161/cc.20009. Epub 2012 Apr 15.

19.

Valproic acid downregulates Cdk5 activity via the transcription of the p35 mRNA.

Takahashi M, Ishida M, Saito T, Ohshima T, Hisanaga S.

Biochem Biophys Res Commun. 2014 May 16;447(4):678-82. doi: 10.1016/j.bbrc.2014.04.072. Epub 2014 Apr 19.

PMID:
24755075
20.

Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium.

Jordà EG, Verdaguer E, Canudas AM, Jiménez A, Garcia de Arriba S, Allgaier C, Pallàs M, Camins A.

Neuroscience. 2005;134(3):1001-11.

PMID:
15979805
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