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Results: 1 to 20 of 113

1.

The nucleotide synthesis enzyme CAD inhibits NOD2 antibacterial function in human intestinal epithelial cells.

Richmond AL, Kabi A, Homer CR, Marina-García N, Nickerson KP, Nesvizhskii AI, Sreekumar A, Chinnaiyan AM, Nuñez G, McDonald C.

Gastroenterology. 2012 Jun;142(7):1483-92.e6. doi: 10.1053/j.gastro.2012.02.040. Epub 2012 Feb 28.

PMID:
22387394
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.

Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C.

Gastroenterology. 2010 Nov;139(5):1630-41, 1641.e1-2. doi: 10.1053/j.gastro.2010.07.006. Epub 2010 Jul 14.

PMID:
20637199
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A dual role for receptor-interacting protein kinase 2 (RIP2) kinase activity in nucleotide-binding oligomerization domain 2 (NOD2)-dependent autophagy.

Homer CR, Kabi A, Marina-García N, Sreekumar A, Nesvizhskii AI, Nickerson KP, Chinnaiyan AM, Nuñez G, McDonald C.

J Biol Chem. 2012 Jul 20;287(30):25565-76. doi: 10.1074/jbc.M111.326835. Epub 2012 Jun 4.

PMID:
22665475
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of carbamoyl phosphate synthetase by MAP kinase.

Graves LM, Guy HI, Kozlowski P, Huang M, Lazarowski E, Pope RM, Collins MA, Dahlstrand EN, Earp HS 3rd, Evans DR.

Nature. 2000 Jan 20;403(6767):328-32.

PMID:
10659854
[PubMed - indexed for MEDLINE]
5.

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells.

Hisamatsu T, Suzuki M, Reinecker HC, Nadeau WJ, McCormick BA, Podolsky DK.

Gastroenterology. 2003 Apr;124(4):993-1000.

PMID:
12671896
[PubMed - indexed for MEDLINE]
6.

TLE1 modifies the effects of NOD2 in the pathogenesis of Crohn's disease.

Nimmo ER, Stevens C, Phillips AM, Smith A, Drummond HE, Noble CL, Quail M, Davies G, Aldhous MC, Wilson DC, Satsangi J.

Gastroenterology. 2011 Sep;141(3):972-981.e1-2. doi: 10.1053/j.gastro.2011.05.043. Epub 2011 May 27.

PMID:
21699783
[PubMed - indexed for MEDLINE]
7.

Association of the NOD2 genotype with bacterial translocation via altered cell-cell contacts in Crohn's disease patients.

Kosovac K, Brenmoehl J, Holler E, Falk W, Schoelmerich J, Hausmann M, Rogler G.

Inflamm Bowel Dis. 2010 Aug;16(8):1311-21. doi: 10.1002/ibd.21223.

PMID:
20232407
[PubMed - indexed for MEDLINE]
8.

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells.

Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC, Podolsky DK.

J Biol Chem. 2005 May 13;280(19):19021-6. Epub 2005 Mar 7.

PMID:
15753091
[PubMed - indexed for MEDLINE]
Free Article
9.

The intermediate filament protein, vimentin, is a regulator of NOD2 activity.

Stevens C, Henderson P, Nimmo ER, Soares DC, Dogan B, Simpson KW, Barrett JC; International Inflammatory Bowel Disease Genetics Consortium, Wilson DC, Satsangi J.

Gut. 2013 May;62(5):695-707. doi: 10.1136/gutjnl-2011-301775. Epub 2012 Jun 8. Erratum in: Gut. 2013 May;62(5):707.

PMID:
22684479
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1.

Zhao Y, Alonso C, Ballester I, Song JH, Chang SY, Guleng B, Arihiro S, Murray PJ, Xavier R, Kobayashi KS, Reinecker HC.

Inflamm Bowel Dis. 2012 Apr;18(4):603-12. doi: 10.1002/ibd.21851. Epub 2011 Sep 1.

PMID:
21887730
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process.

Lecat A, Di Valentin E, Somja J, Jourdan S, Fillet M, Kufer TA, Habraken Y, Sadzot C, Louis E, Delvenne P, Piette J, Legrand-Poels S.

J Biol Chem. 2012 Aug 24;287(35):29213-26. doi: 10.1074/jbc.M112.355545. Epub 2012 Jun 14.

PMID:
22700971
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy.

Nguyen HT, Dalmasso G, Müller S, Carrière J, Seibold F, Darfeuille-Michaud A.

Gastroenterology. 2014 Feb;146(2):508-19. doi: 10.1053/j.gastro.2013.10.021. Epub 2013 Oct 19.

PMID:
24148619
[PubMed - indexed for MEDLINE]
14.

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.

Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M.

Science. 2005 Feb 4;307(5710):734-8. Erratum in: Science. 2011 Jul 15;333(6040):288. Science. 2005 Apr 29;308(5722):633.

PMID:
15692052
[PubMed - indexed for MEDLINE]
Free Article
15.

Localization of the multifunctional protein CAD in astrocytes of rodent brain.

Cammer W, Downing M.

J Histochem Cytochem. 1991 May;39(5):695-700.

PMID:
1673139
[PubMed - indexed for MEDLINE]
16.

miR-122 targets NOD2 to decrease intestinal epithelial cell injury in Crohn's disease.

Chen Y, Wang C, Liu Y, Tang L, Zheng M, Xu C, Song J, Meng X.

Biochem Biophys Res Commun. 2013 Aug 16;438(1):133-9. doi: 10.1016/j.bbrc.2013.07.040. Epub 2013 Jul 19.

PMID:
23872065
[PubMed - indexed for MEDLINE]
17.

Activation of NOD2-mediated intestinal pathway in a pediatric population with Crohn's disease.

Negroni A, Stronati L, Pierdomenico M, Tirindelli D, Di Nardo G, Mancini V, Maiella G, Cucchiara S.

Inflamm Bowel Dis. 2009 Aug;15(8):1145-54. doi: 10.1002/ibd.20907.

PMID:
19266573
[PubMed - indexed for MEDLINE]
18.

A new look at Crohn's disease: breakdown of the mucosal antibacterial defense.

Wehkamp J, Stange EF.

Ann N Y Acad Sci. 2006 Aug;1072:321-31. Review.

PMID:
17057212
[PubMed - indexed for MEDLINE]
19.

The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD.

Lindsey-Boltz LA, Wauson EM, Graves LM, Sancar A.

Nucleic Acids Res. 2004 Aug 23;32(15):4524-30. Print 2004.

PMID:
15326225
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Transcriptional repression of human cad gene by hypoxia inducible factor-1alpha.

Chen KF, Lai YY, Sun HS, Tsai SJ.

Nucleic Acids Res. 2005 Sep 9;33(16):5190-8. Print 2005.

PMID:
16155188
[PubMed - indexed for MEDLINE]
Free PMC Article

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