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Results: 1 to 20 of 100

1.

The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

Lubke GH, Stephens SH, Lessem JM, Hewitt JK, Ehringer MA.

Behav Genet. 2012 Jul;42(4):636-46. doi: 10.1007/s10519-012-9529-y. Epub 2012 Mar 1.

PMID:
22382757
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.

Schlaepfer IR, Hoft NR, Collins AC, Corley RP, Hewitt JK, Hopfer CJ, Lessem JM, McQueen MB, Rhee SH, Ehringer MA.

Biol Psychiatry. 2008 Jun 1;63(11):1039-46. doi: 10.1016/j.biopsych.2007.10.024. Epub 2007 Dec 27. Erratum in: Biol Psychiatry. 2011 May 1;69(9):905-6.

PMID:
18163978
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.

Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Han Y, Hansel NN, Jiang C, Korhonen T, Lind PA, Liu J, Lyytikäinen LP, Michel M, Shaffer JR, Short SE, Sun J, Teumer A, Thompson JR, Vogelzangs N, Vink JM, Wenzlaff A, Wheeler W, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty TH, Benjamin DJ, Bergen AW, Broms U, Cesarini D, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick D, Foroud T, Furberg H, Giegling I, Gillespie NA, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Heikkilä K, Hickie IB, Hottenga JJ, Jousilahti P, Kaakinen M, Kähönen M, Koellinger PD, Kittner S, Konte B, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Murray T, Nauck M, North KE, Paré PD, Pergadia M, Ruczinski I, Salomaa V, Viikari J, Willemsen G, Barnes KC, Boerwinkle E, Boomsma DI, Caporaso N, Edenberg HJ, Francks C, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Johannesson M, Kendler KS, Lehtimäki T, Magnusson PK, Marazita ML, Marchini J, Mitchell BD, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Schwartz AG, Shete S, Spitz M, Swan GE, Völzke H, Veijola J, Wei Q, Amos C, Cannon DS, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA.

Genet Epidemiol. 2013 Dec;37(8):846-59. doi: 10.1002/gepi.21760. Epub 2013 Nov 1.

PMID:
24186853
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study.

Choquet H, Joslyn G, Lee A, Kasberger J, Robertson M, Brush G, Schuckit MA, White R, Jorgenson E.

Alcohol Clin Exp Res. 2013 Aug;37(8):1311-6. doi: 10.1111/acer.12099. Epub 2013 Mar 4.

PMID:
23458267
[PubMed - indexed for MEDLINE]
5.

Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.

Li MD, Yoon D, Lee JY, Han BG, Niu T, Payne TJ, Ma JZ, Park T.

PLoS One. 2010 Aug 16;5(8):e12183. doi: 10.1371/journal.pone.0012183.

PMID:
20808433
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

Baker TB, Weiss RB, Bolt D, von Niederhausern A, Fiore MC, Dunn DM, Piper ME, Matsunami N, Smith SS, Coon H, McMahon WM, Scholand MB, Singh N, Hoidal JR, Kim SY, Leppert MF, Cannon DS.

Nicotine Tob Res. 2009 Jul;11(7):785-96. doi: 10.1093/ntr/ntp064. Epub 2009 May 12.

PMID:
19436041
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users.

Zhu AZ, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF.

Addiction. 2013 Oct;108(10):1818-28. doi: 10.1111/add.12250. Epub 2013 Jul 5.

PMID:
23692359
[PubMed - indexed for MEDLINE]
8.

Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.

Li MD, Xu Q, Lou XY, Payne TJ, Niu T, Ma JZ.

Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B(3):745-56. doi: 10.1002/ajmg.b.31043.

PMID:
19859904
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.

Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, Murtra P, Armengol L, Fernández-Montes RD, Gratacòs M, Pumarola M, Cabrera R, Maldonado R, Sabrià J, Estivill X, Dierssen M.

Amino Acids. 2012 Aug;43(2):897-909. doi: 10.1007/s00726-011-1149-y. Epub 2011 Nov 19.

PMID:
22101982
[PubMed - indexed for MEDLINE]
10.

Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes.

Chen LS, Xian H, Grucza RA, Saccone NL, Wang JC, Johnson EO, Breslau N, Hatsukami D, Bierut LJ.

Drug Alcohol Depend. 2012 Jun;123 Suppl 1:S42-51. doi: 10.1016/j.drugalcdep.2012.01.014. Epub 2012 Feb 13.

PMID:
22336398
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

Broms U, Wedenoja J, Largeau MR, Korhonen T, Pitkäniemi J, Keskitalo-Vuokko K, Häppölä A, Heikkilä KH, Heikkilä K, Ripatti S, Sarin AP, Salminen O, Paunio T, Pergadia ML, Madden PA, Kaprio J, Loukola A.

Nicotine Tob Res. 2012 Jun;14(6):720-33. doi: 10.1093/ntr/ntr283. Epub 2012 Jan 12.

PMID:
22241830
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

From men to mice: CHRNA5/CHRNA3, smoking behavior and disease.

Ware JJ, van den Bree M, Munafò MR.

Nicotine Tob Res. 2012 Nov;14(11):1291-9. doi: 10.1093/ntr/nts106. Epub 2012 Apr 27. Review.

PMID:
22544838
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.

Winterer G, Mittelstrass K, Giegling I, Lamina C, Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat J, Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller HJ, Gieger C, Wichmann HE, Illig T, Dahmen N, Rujescu D.

Am J Med Genet B Neuropsychiatr Genet. 2010 Dec 5;153B(8):1448-58. doi: 10.1002/ajmg.b.31126. Epub 2010 Sep 30.

PMID:
20886544
[PubMed - indexed for MEDLINE]
14.

Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis.

Ware JJ, van den Bree MB, Munafò MR.

Nicotine Tob Res. 2011 Dec;13(12):1167-75. doi: 10.1093/ntr/ntr118. Epub 2011 Nov 9. Review.

PMID:
22071378
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Association of CHRNA5-A3-B4 variation with esophageal squamous cell carcinoma risk and smoking behaviors in a Chinese population.

Wang Y, Wu H, Liu Q, Wang C, Fu L, Wang H, Zhu W, Fu W, Lv Y, Wang S, Hu L.

PLoS One. 2013 Jul 2;8(7):e67664. doi: 10.1371/journal.pone.0067664. Print 2013.

PMID:
23844051
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Is susceptibility locus for lung cancer in the 15q25 nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 associated with risk of gastric cancer?

Wu H, Wang Y, Wang S, Jiang M, Wang C, Fu W, Hu L.

Med Oncol. 2013;30(2):576. doi: 10.1007/s12032-013-0576-x. Epub 2013 Apr 11.

PMID:
23576140
[PubMed - indexed for MEDLINE]
17.

The CHRNA5-A3-B4 gene cluster in nicotine addiction.

Berrettini WH, Doyle GA.

Mol Psychiatry. 2012 Sep;17(9):856-66. doi: 10.1038/mp.2011.122. Epub 2011 Oct 4. Review.

PMID:
21968931
[PubMed - indexed for MEDLINE]
18.

A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.

Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF.

PLoS Genet. 2008 Jul 11;4(7):e1000125. doi: 10.1371/journal.pgen.1000125.

PMID:
18618000
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Association of a variant in the CHRNA5-A3-B4 gene cluster region to heavy smoking in the Italian population.

Sorice R, Bione S, Sansanelli S, Ulivi S, Athanasakis E, Lanzara C, Nutile T, Sala C, Camaschella C, D'Adamo P, Gasparini P, Ciullo M, Toniolo D.

Eur J Hum Genet. 2011 May;19(5):593-6. doi: 10.1038/ejhg.2010.240. Epub 2011 Jan 19.

PMID:
21248747
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A twin association study of nicotine dependence with markers in the CHRNA3 and CHRNA5 genes.

Maes HH, Neale MC, Chen X, Chen J, Prescott CA, Kendler KS.

Behav Genet. 2011 Sep;41(5):680-90. doi: 10.1007/s10519-011-9476-z. Epub 2011 Jul 12.

PMID:
21748402
[PubMed - indexed for MEDLINE]
Free PMC Article

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