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Results: 1 to 20 of 102

1.

Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study.

Gadd S, Beezhold P, Jennings L, George D, Leuer K, Huang CC, Huff V, Tognon C, Sorensen PH, Triche T, Coffin CM, Perlman EJ.

J Pathol. 2012 Sep;228(1):119-30. doi: 10.1002/path.4010. Epub 2012 Jul 2.

PMID:
22374738
[PubMed - indexed for MEDLINE]
2.

Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma.

Rubin BP, Chen CJ, Morgan TW, Xiao S, Grier HE, Kozakewich HP, Perez-Atayde AR, Fletcher JA.

Am J Pathol. 1998 Nov;153(5):1451-8.

PMID:
9811336
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma.

Knezevich SR, Garnett MJ, Pysher TJ, Beckwith JB, Grundy PE, Sorensen PH.

Cancer Res. 1998 Nov 15;58(22):5046-8.

PMID:
9823307
[PubMed - indexed for MEDLINE]
Free Article
4.

Cryptic t(12;15)(p13;q26) producing the ETV6-NTRK3 fusion gene and no loss of IGF2 imprinting in congenital mesoblastic nephroma with trisomy 11: fluorescence in situ hybridization and IGF2 allelic expression analysis.

Watanabe N, Kobayashi H, Hirama T, Kikuta A, Koizumi S, Tsuru T, Kaneko Y.

Cancer Genet Cytogenet. 2002 Jul 1;136(1):10-6.

PMID:
12165445
[PubMed - indexed for MEDLINE]
5.

ETV6 rearrangements in patients with infantile fibrosarcomas and congenital mesoblastic nephromas by fluorescence in situ hybridization.

Adem C, Gisselsson D, Dal Cin P, Nascimento AG.

Mod Pathol. 2001 Dec;14(12):1246-51.

PMID:
11743047
[PubMed - indexed for MEDLINE]
Free Article
6.
7.

The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.

Tognon C, Garnett M, Kenward E, Kay R, Morrison K, Sorensen PH.

Cancer Res. 2001 Dec 15;61(24):8909-16.

PMID:
11751416
[PubMed - indexed for MEDLINE]
Free Article
8.

ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation.

Morrison KB, Tognon CE, Garnett MJ, Deal C, Sorensen PH.

Oncogene. 2002 Aug 22;21(37):5684-95.

PMID:
12173038
[PubMed - indexed for MEDLINE]
Free Article
9.

Cellular mesoblastic nephroma: morphologic, cytogenetic and molecular links with congenital fibrosarcoma.

Henno S, Loeuillet L, Henry C, D'Hervé D, Azzis O, Ferrer J, Poulain P, Babut JM, Merlio JP, Jouan H, Dubus P.

Pathol Res Pract. 2003;199(1):35-40.

PMID:
12650516
[PubMed - indexed for MEDLINE]
10.

The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells.

Wai DH, Knezevich SR, Lucas T, Jansen B, Kay RJ, Sorensen PH.

Oncogene. 2000 Feb 17;19(7):906-15.

PMID:
10702799
[PubMed - indexed for MEDLINE]
Free Article
11.

Non-resectable congenital tumors with the ETV6-NTRK3 gene fusion are highly responsive to chemotherapy.

McCahon E, Sorensen PH, Davis JH, Rogers PC, Schultz KR.

Med Pediatr Oncol. 2003 May;40(5):288-92.

PMID:
12652616
[PubMed - indexed for MEDLINE]
12.

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma.

Knezevich SR, McFadden DE, Tao W, Lim JF, Sorensen PH.

Nat Genet. 1998 Feb;18(2):184-7.

PMID:
9462753
[PubMed - indexed for MEDLINE]
13.

Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors.

Bourgeois JM, Knezevich SR, Mathers JA, Sorensen PH.

Am J Surg Pathol. 2000 Jul;24(7):937-46.

PMID:
10895816
[PubMed - indexed for MEDLINE]
14.

Congenital-infantile fibrosarcoma. A clinicopathologic study of 10 cases and molecular detection of the ETV6-NTRK3 fusion transcripts using paraffin-embedded tissues.

Sheng WQ, Hisaoka M, Okamoto S, Tanaka A, Meis-Kindblom JM, Kindblom LG, Ishida T, Nojima T, Hashimoto H.

Am J Clin Pathol. 2001 Mar;115(3):348-55.

PMID:
11242790
[PubMed - indexed for MEDLINE]
Free Article
15.

Mixed epithelial and stromal tumor of the kidney lacks the genetic alterations of cellular congenital mesoblastic nephroma.

Pierson CR, Schober MS, Wallis T, Sarkar FH, Sorensen PH, Eble JN, Srigley JR, Jones EC, Grignon DJ, Adsay V.

Hum Pathol. 2001 May;32(5):513-20.

PMID:
11381370
[PubMed - indexed for MEDLINE]
16.

Cellular transformation and activation of the phosphoinositide-3-kinase-Akt cascade by the ETV6-NTRK3 chimeric tyrosine kinase requires c-Src.

Jin W, Yun C, Hobbie A, Martin MJ, Sorensen PH, Kim SJ.

Cancer Res. 2007 Apr 1;67(7):3192-200.

PMID:
17409427
[PubMed - indexed for MEDLINE]
Free Article
17.

A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Lannon CL, Martin MJ, Tognon CE, Jin W, Kim SJ, Sorensen PH.

J Biol Chem. 2004 Feb 20;279(8):6225-34. Epub 2003 Dec 9.

PMID:
14668342
[PubMed - indexed for MEDLINE]
Free Article
18.

Expression of ETV6-NTRK in classical, cellular and mixed subtypes of congenital mesoblastic nephroma.

Anderson J, Gibson S, Sebire NJ.

Histopathology. 2006 May;48(6):748-53.

PMID:
16681692
[PubMed - indexed for MEDLINE]
19.

Duplication of the paternal IGF2 allele in trisomy 11 and elevated expression levels of IGF2 mRNA in congenital mesoblastic nephroma of the cellular or mixed type.

Watanabe N, Haruta M, Soejima H, Fukushi D, Yokomori K, Nakadate H, Okita H, Hata JI, Fukuzawa M, Kaneko Y.

Genes Chromosomes Cancer. 2007 Oct;46(10):929-35.

PMID:
17639583
[PubMed - indexed for MEDLINE]
20.

Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity.

Tognon CE, Mackereth CD, Somasiri AM, McIntosh LP, Sorensen PH.

Mol Cell Biol. 2004 Jun;24(11):4636-50.

PMID:
15143160
[PubMed - indexed for MEDLINE]
Free PMC Article

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