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Results: 1 to 20 of 82

1.

Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death.

Brohem CA, Massaro RR, Tiago M, Marinho CE, Jasiulionis MG, de Almeida RL, Rivelli DP, Albuquerque RC, de Oliveira TF, de Melo Loureiro AP, Okada S, Soengas MS, de Moraes Barros SB, Maria-Engler SS.

Pigment Cell Melanoma Res. 2012 May;25(3):354-69. doi: 10.1111/j.1755-148X.2012.00992.x. Epub 2012 Mar 27.

PMID:
22372875
[PubMed - indexed for MEDLINE]
2.

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status.

Pérez-Galán P, Roué G, Villamor N, Montserrat E, Campo E, Colomer D.

Blood. 2006 Jan 1;107(1):257-64. Epub 2005 Sep 15.

PMID:
16166592
[PubMed - indexed for MEDLINE]
Free Article
3.

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells.

Ling YH, Liebes L, Zou Y, Perez-Soler R.

J Biol Chem. 2003 Sep 5;278(36):33714-23. Epub 2003 Jun 23.

PMID:
12821677
[PubMed - indexed for MEDLINE]
Free Article
4.

Apoptosis induction by 4-nerolidylcatechol in melanoma cell lines.

Brohem CA, Sawada TC, Massaro RR, Almeida RL, Rivelli DP, Ropke CD, da Silva VV, de Lima TM, Curi R, Barros SB, Maria-Engler SS.

Toxicol In Vitro. 2009 Feb;23(1):111-9. doi: 10.1016/j.tiv.2008.11.004. Epub 2008 Nov 24.

PMID:
19059332
[PubMed - indexed for MEDLINE]
5.

Chemical blockage of the proteasome inhibitory function of bortezomib: impact on tumor cell death.

Fernández Y, Miller TP, Denoyelle C, Esteban JA, Tang WH, Bengston AL, Soengas MS.

J Biol Chem. 2006 Jan 13;281(2):1107-18. Epub 2005 Nov 8.

PMID:
16278210
[PubMed - indexed for MEDLINE]
Free Article
6.

Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.

Fernández Y, Verhaegen M, Miller TP, Rush JL, Steiner P, Opipari AW Jr, Lowe SW, Soengas MS.

Cancer Res. 2005 Jul 15;65(14):6294-304.

PMID:
16024631
[PubMed - indexed for MEDLINE]
Free Article
7.

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells.

Qin JZ, Ziffra J, Stennett L, Bodner B, Bonish BK, Chaturvedi V, Bennett F, Pollock PM, Trent JM, Hendrix MJ, Rizzo P, Miele L, Nickoloff BJ.

Cancer Res. 2005 Jul 15;65(14):6282-93.

PMID:
16024630
[PubMed - indexed for MEDLINE]
Free Article
8.

Differential sensitivity of breast cancer and melanoma cells to proteasome inhibitor Velcade.

Yerlikaya A, Erin N.

Int J Mol Med. 2008 Dec;22(6):817-23.

PMID:
19020781
[PubMed - indexed for MEDLINE]
9.

Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines.

Maurer BJ, Metelitsa LS, Seeger RC, Cabot MC, Reynolds CP.

J Natl Cancer Inst. 1999 Jul 7;91(13):1138-46.

PMID:
10393722
[PubMed - indexed for MEDLINE]
Free Article
10.

Gallic acid induces apoptosis in A375.S2 human melanoma cells through caspase-dependent and -independent pathways.

Lo C, Lai TY, Yang JH, Yang JS, Ma YS, Weng SW, Chen YY, Lin JG, Chung JG.

Int J Oncol. 2010 Aug;37(2):377-85.

PMID:
20596665
[PubMed - indexed for MEDLINE]
11.

Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib.

Chen S, Blank JL, Peters T, Liu XJ, Rappoli DM, Pickard MD, Menon S, Yu J, Driscoll DL, Lingaraj T, Burkhardt AL, Chen W, Garcia K, Sappal DS, Gray J, Hales P, Leroy PJ, Ringeling J, Rabino C, Spelman JJ, Morgenstern JP, Lightcap ES.

Cancer Res. 2010 Jun 1;70(11):4318-26. doi: 10.1158/0008-5472.CAN-09-4428. Epub 2010 May 11.

PMID:
20460535
[PubMed - indexed for MEDLINE]
Free Article
12.

Molecular study on copper-mediated tumor proteasome inhibition and cell death.

Xiao Y, Chen D, Zhang X, Cui Q, Fan Y, Bi C, Dou QP.

Int J Oncol. 2010 Jul;37(1):81-7.

PMID:
20514399
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Effect of proteasome inhibitors on proliferation and apoptosis of human cutaneous melanoma-derived cell lines.

Sorolla A, Yeramian A, Dolcet X, Pérez de Santos AM, Llobet D, Schoenenberger JA, Casanova JM, Soria X, Egido R, Llombart A, Vilella R, Matias-Guiu X, Marti RM.

Br J Dermatol. 2008 Mar;158(3):496-504. doi: 10.1111/j.1365-2133.2007.08390.x. Epub 2008 Jan 17.

PMID:
18205878
[PubMed - indexed for MEDLINE]
14.
15.

BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells.

Kurosu T, Fukuda T, Miki T, Miura O.

Oncogene. 2003 Jul 17;22(29):4459-68.

PMID:
12881702
[PubMed - indexed for MEDLINE]
16.

BH3 mimetic ABT-737 and a proteasome inhibitor synergistically kill melanomas through Noxa-dependent apoptosis.

Miller LA, Goldstein NB, Johannes WU, Walton CH, Fujita M, Norris DA, Shellman YG.

J Invest Dermatol. 2009 Apr;129(4):964-71. doi: 10.1038/jid.2008.327. Epub 2008 Nov 6.

PMID:
18987671
[PubMed - indexed for MEDLINE]
Free Article
17.

Proteasome inhibition improves fractionated radiation treatment against non-small cell lung cancer: an antioxidant connection.

Grimes KR, Daosukho C, Zhao Y, Meigooni A, St Clair W.

Int J Oncol. 2005 Oct;27(4):1047-52.

PMID:
16142322
[PubMed - indexed for MEDLINE]
18.

Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.

Qin JZ, Xin H, Sitailo LA, Denning MF, Nickoloff BJ.

Cancer Res. 2006 Oct 1;66(19):9636-45.

PMID:
17018621
[PubMed - indexed for MEDLINE]
Free Article
19.

Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma.

Kuhn DJ, Chen Q, Voorhees PM, Strader JS, Shenk KD, Sun CM, Demo SD, Bennett MK, van Leeuwen FW, Chanan-Khan AA, Orlowski RZ.

Blood. 2007 Nov 1;110(9):3281-90. Epub 2007 Jun 25.

PMID:
17591945
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Therapeutic window for melanoma treatment provided by selective effects of the proteasome on Bcl-2 proteins.

Wolter KG, Verhaegen M, Fernández Y, Nikolovska-Coleska Z, Riblett M, de la Vega CM, Wang S, Soengas MS.

Cell Death Differ. 2007 Sep;14(9):1605-16. Epub 2007 Jun 1.

PMID:
17541428
[PubMed - indexed for MEDLINE]
Free Article

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