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Results: 1 to 20 of 123

1.

The heat shock response: systems biology of proteotoxic stress in aging and disease.

Morimoto RI.

Cold Spring Harb Symp Quant Biol. 2011;76:91-9. doi: 10.1101/sqb.2012.76.010637. Epub 2012 Feb 27. Review.

PMID:
22371371
[PubMed - indexed for MEDLINE]
2.

Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling.

van Oosten-Hawle P, Morimoto RI.

Genes Dev. 2014 Jul 15;28(14):1533-43. doi: 10.1101/gad.241125.114. Review.

PMID:
25030693
[PubMed - indexed for MEDLINE]
3.

Transcellular chaperone signaling: an organismal strategy for integrated cell stress responses.

van Oosten-Hawle P, Morimoto RI.

J Exp Biol. 2014 Jan 1;217(Pt 1):129-36. doi: 10.1242/jeb.091249. Review.

PMID:
24353212
[PubMed - indexed for MEDLINE]
Free Article
4.

The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones.

Morimoto RI, Kline MP, Bimston DN, Cotto JJ.

Essays Biochem. 1997;32:17-29. Review.

PMID:
9493008
[PubMed - indexed for MEDLINE]
5.

The shock of aging: molecular chaperones and the heat shock response in longevity and aging--a mini-review.

Calderwood SK, Murshid A, Prince T.

Gerontology. 2009;55(5):550-8. doi: 10.1159/000225957. Epub 2009 Jun 18. Review.

PMID:
19546513
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging.

Morimoto RI.

Genes Dev. 2008 Jun 1;22(11):1427-38. doi: 10.1101/gad.1657108. Review.

PMID:
18519635
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Small molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise.

West JD, Wang Y, Morano KA.

Chem Res Toxicol. 2012 Oct 15;25(10):2036-53. doi: 10.1021/tx300264x. Epub 2012 Jul 31. Review.

PMID:
22799889
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease.

Jovaisaite V, Mouchiroud L, Auwerx J.

J Exp Biol. 2014 Jan 1;217(Pt 1):137-43. doi: 10.1242/jeb.090738. Review.

PMID:
24353213
[PubMed - indexed for MEDLINE]
Free Article
9.

The stress of protein misfolding: from single cells to multicellular organisms.

Gidalevitz T, Prahlad V, Morimoto RI.

Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6). pii: a009704. doi: 10.1101/cshperspect.a009704. Review.

PMID:
21536706
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Integrating the stress response: lessons for neurodegenerative diseases from C. elegans.

Prahlad V, Morimoto RI.

Trends Cell Biol. 2009 Feb;19(2):52-61. doi: 10.1016/j.tcb.2008.11.002. Epub 2008 Dec 26. Review.

PMID:
19112021
[PubMed - indexed for MEDLINE]
11.

Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.

Calabrese V, Scapagnini G, Colombrita C, Ravagna A, Pennisi G, Giuffrida Stella AM, Galli F, Butterfield DA.

Amino Acids. 2003 Dec;25(3-4):437-44. Epub 2003 Nov 7. Review.

PMID:
14661103
[PubMed - indexed for MEDLINE]
12.

Redox homeostasis and cellular stress response in aging and neurodegeneration.

Calabrese V, Cornelius C, Mancuso C, Lentile R, Stella AM, Butterfield DA.

Methods Mol Biol. 2010;610:285-308. doi: 10.1007/978-1-60327-029-8_17.

PMID:
20013185
[PubMed - indexed for MEDLINE]
13.

HSF transcription factor family, heat shock response, and protein intrinsic disorder.

Westerheide SD, Raynes R, Powell C, Xue B, Uversky VN.

Curr Protein Pept Sci. 2012 Feb;13(1):86-103. Review.

PMID:
22044151
[PubMed - indexed for MEDLINE]
14.

A natural extracellular factor that induces Hsp72, inhibits apoptosis, and restores stress resistance in aged human cells.

Volloch V, Rits S.

Exp Cell Res. 1999 Dec 15;253(2):483-92.

PMID:
10585271
[PubMed - indexed for MEDLINE]
15.

Modelling the actions of chaperones and their role in ageing.

Proctor CJ, Soti C, Boys RJ, Gillespie CS, Shanley DP, Wilkinson DJ, Kirkwood TB.

Mech Ageing Dev. 2005 Jan;126(1):119-31.

PMID:
15610770
[PubMed - indexed for MEDLINE]
16.

Cellular stress responses, mitostress and carnitine insufficiencies as critical determinants in aging and neurodegenerative disorders: role of hormesis and vitagenes.

Calabrese V, Cornelius C, Stella AM, Calabrese EJ.

Neurochem Res. 2010 Dec;35(12):1880-915. doi: 10.1007/s11064-010-0307-z. Epub 2010 Nov 13.

PMID:
21080068
[PubMed - indexed for MEDLINE]
17.

A neuronal GPCR is critical for the induction of the heat shock response in the nematode C. elegans.

Maman M, Carvalhal Marques F, Volovik Y, Dubnikov T, Bejerano-Sagie M, Cohen E.

J Neurosci. 2013 Apr 3;33(14):6102-11. doi: 10.1523/JNEUROSCI.4023-12.2013.

PMID:
23554491
[PubMed - indexed for MEDLINE]
Free Article
18.

Stress-induced activation of the heat-shock response: cell and molecular biology of heat-shock factors.

Cotto JJ, Morimoto RI.

Biochem Soc Symp. 1999;64:105-18. Review.

PMID:
10207624
[PubMed - indexed for MEDLINE]
19.

Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway.

Ali YO, McCormack R, Darr A, Zhai RG.

J Biol Chem. 2011 May 27;286(21):19089-99. doi: 10.1074/jbc.M111.219295. Epub 2011 Apr 8.

PMID:
21478149
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis.

Lindquist SL, Kelly JW.

Cold Spring Harb Perspect Biol. 2011 Dec 1;3(12). pii: a004507. doi: 10.1101/cshperspect.a004507. Review.

PMID:
21900404
[PubMed - indexed for MEDLINE]
Free PMC Article

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