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Items: 1 to 20 of 173

1.

An equilibrium model for linear and closed-loop amyloid fibril formation.

Yang S, Griffin MD, Binger KJ, Schuck P, Howlett GJ.

J Mol Biol. 2012 Aug 10;421(2-3):364-77. doi: 10.1016/j.jmb.2012.02.026. Epub 2012 Feb 24.

2.

Phospholipids enhance nucleation but not elongation of apolipoprotein C-II amyloid fibrils.

Ryan TM, Teoh CL, Griffin MD, Bailey MF, Schuck P, Howlett GJ.

J Mol Biol. 2010 Jun 25;399(5):731-40. doi: 10.1016/j.jmb.2010.04.042. Epub 2010 Apr 28.

3.

Apolipoprotein C-II amyloid fibrils assemble via a reversible pathway that includes fibril breaking and rejoining.

Binger KJ, Pham CL, Wilson LM, Bailey MF, Lawrence LJ, Schuck P, Howlett GJ.

J Mol Biol. 2008 Feb 29;376(4):1116-29. doi: 10.1016/j.jmb.2007.12.055. Epub 2008 Jan 3.

PMID:
18206908
4.

Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II.

Ryan TM, Howlett GJ, Bailey MF.

J Biol Chem. 2008 Dec 12;283(50):35118-28. doi: 10.1074/jbc.M804004200. Epub 2008 Oct 13.

5.

Shear flow induced changes in apolipoprotein C-II conformation and amyloid fibril formation.

Teoh CL, Bekard IB, Asimakis P, Griffin MD, Ryan TM, Dunstan DE, Howlett GJ.

Biochemistry. 2011 May 17;50(19):4046-57. doi: 10.1021/bi2002482. Epub 2011 Apr 22.

PMID:
21476595
6.

A structural model for apolipoprotein C-II amyloid fibrils: experimental characterization and molecular dynamics simulations.

Teoh CL, Pham CL, Todorova N, Hung A, Lincoln CN, Lees E, Lam YH, Binger KJ, Thomson NH, Radford SE, Smith TA, Müller SA, Engel A, Griffin MD, Yarovsky I, Gooley PR, Howlett GJ.

J Mol Biol. 2011 Feb 4;405(5):1246-66. doi: 10.1016/j.jmb.2010.12.006. Epub 2010 Dec 10.

PMID:
21146539
7.

Charge and charge-pair mutations alter the rate of assembly and structural properties of apolipoprotein C-II amyloid fibrils.

Mao Y, Teoh CL, Yang S, Zlatic CO, Rosenes ZK, Gooley PR, Howlett GJ, Griffin MD.

Biochemistry. 2015 Feb 17;54(6):1421-8. doi: 10.1021/bi5014535. Epub 2015 Feb 2.

PMID:
25609257
8.

High-affinity amphipathic modulators of amyloid fibril nucleation and elongation.

Ryan TM, Griffin MD, Teoh CL, Ooi J, Howlett GJ.

J Mol Biol. 2011 Feb 25;406(3):416-29. doi: 10.1016/j.jmb.2010.12.023. Epub 2010 Dec 23.

PMID:
21185302
9.

Visualization of polymorphism in apolipoprotein C-II amyloid fibrils.

Teoh CL, Yagi H, Griffin MD, Goto Y, Howlett GJ.

J Biochem. 2011 Jan;149(1):67-74. doi: 10.1093/jb/mvq117. Epub 2010 Sep 30.

PMID:
20889492
10.

NBD-labeled phospholipid accelerates apolipoprotein C-II amyloid fibril formation but is not incorporated into mature fibrils.

Ryan TM, Griffin MD, Bailey MF, Schuck P, Howlett GJ.

Biochemistry. 2011 Nov 8;50(44):9579-86. doi: 10.1021/bi201192r. Epub 2011 Oct 13.

11.

A structural core within apolipoprotein C-II amyloid fibrils identified using hydrogen exchange and proteolysis.

Wilson LM, Mok YF, Binger KJ, Griffin MD, Mertens HD, Lin F, Wade JD, Gooley PR, Howlett GJ.

J Mol Biol. 2007 Mar 9;366(5):1639-51. Epub 2006 Dec 21.

PMID:
17217959
12.

Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils.

Binger KJ, Ecroyd H, Yang S, Carver JA, Howlett GJ, Griffin MD.

FASEB J. 2013 Mar;27(3):1214-22. doi: 10.1096/fj.12-220657. Epub 2012 Nov 16.

13.

Fluphenazine·HCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils.

Zlatic CO, Mao Y, Ryan TM, Mok YF, Roberts BR, Howlett GJ, Griffin MD.

Biochemistry. 2015 Jun 23;54(24):3831-8. doi: 10.1021/acs.biochem.5b00399. Epub 2015 Jun 12.

PMID:
26021642
14.

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II.

Mao Y, Zlatic CO, Griffin MD, Howlett GJ, Todorova N, Yarovsky I, Gooley PR.

Biochemistry. 2015 Aug 11;54(31):4805-14. doi: 10.1021/acs.biochem.5b00535. Epub 2015 Aug 3.

PMID:
26196342
15.

Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways.

Griffin MD, Mok ML, Wilson LM, Pham CL, Waddington LJ, Perugini MA, Howlett GJ.

J Mol Biol. 2008 Jan 4;375(1):240-56. Epub 2007 Oct 22.

PMID:
18005990
16.

Effect of oxidation and mutation on the conformational dynamics and fibril assembly of amyloidogenic peptides derived from apolipoprotein C-II.

Legge FS, Binger KJ, Griffin MD, Howlett GJ, Scanlon D, Treutlein H, Yarovsky I.

J Phys Chem B. 2009 Oct 22;113(42):14006-14. doi: 10.1021/jp903842u.

PMID:
19780547
17.

Effects of mutation on the amyloidogenic propensity of apolipoprotein C-II(60-70) peptide.

Todorova N, Hung A, Maaser SM, Griffin MD, Karas J, Howlett GJ, Yarovsky I.

Phys Chem Chem Phys. 2010 Nov 28;12(44):14762-74. doi: 10.1039/c0cp00299b. Epub 2010 Oct 11.

PMID:
20938536
18.

Structural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein E.

Gunzburg MJ, Perugini MA, Howlett GJ.

J Biol Chem. 2007 Dec 7;282(49):35831-41. Epub 2007 Oct 4.

19.

Oxidized cholesterol metabolites found in human atherosclerotic lesions promote apolipoprotein C-II amyloid fibril formation.

Stewart CR, Wilson LM, Zhang Q, Pham CL, Waddington LJ, Staples MK, Stapleton D, Kelly JW, Howlett GJ.

Biochemistry. 2007 May 8;46(18):5552-61. Epub 2007 Apr 13.

PMID:
17429947
20.

Methionine oxidation inhibits assembly and promotes disassembly of apolipoprotein C-II amyloid fibrils.

Binger KJ, Griffin MD, Howlett GJ.

Biochemistry. 2008 Sep 23;47(38):10208-17. doi: 10.1021/bi8009339. Epub 2008 Aug 26.

PMID:
18729385
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