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Results: 1 to 20 of 128

1.

Transmission of Synucleinopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice.

Lee HJ, Suk JE, Lee KW, Park SH, Blumbergs PC, Gai WP, Lee SJ.

Exp Neurobiol. 2011 Dec;20(4):181-8. doi: 10.5607/en.2011.20.4.181. Epub 2011 Dec 29.

PMID:
22355263
[PubMed]
Free PMC Article
2.

[Clinical and pathological study on early diagnosis of Parkinson's disease and dementia with Lewy bodies].

Orimo S.

Rinsho Shinkeigaku. 2008 Jan;48(1):11-24. Review. Japanese.

PMID:
18386627
[PubMed - indexed for MEDLINE]
3.

Pathological biochemistry of alpha-synucleinopathy.

Iwatsubo T.

Neuropathology. 2007 Oct;27(5):474-8. Retraction in: Neuropathology. 2012 Jun;32(3):318.

PMID:
18018483
[PubMed - indexed for MEDLINE]
4.

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.

Kuo YM, Li Z, Jiao Y, Gaborit N, Pani AK, Orrison BM, Bruneau BG, Giasson BI, Smeyne RJ, Gershon MD, Nussbaum RL.

Hum Mol Genet. 2010 May 1;19(9):1633-50. doi: 10.1093/hmg/ddq038. Epub 2010 Jan 27.

PMID:
20106867
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Neuropathology in mice expressing human alpha-synuclein.

van der Putten H, Wiederhold KH, Probst A, Barbieri S, Mistl C, Danner S, Kauffmann S, Hofele K, Spooren WP, Ruegg MA, Lin S, Caroni P, Sommer B, Tolnay M, Bilbe G.

J Neurosci. 2000 Aug 15;20(16):6021-9.

PMID:
10934251
[PubMed - indexed for MEDLINE]
Free Article
6.

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

Baba M, Nakajo S, Tu PH, Tomita T, Nakaya K, Lee VM, Trojanowski JQ, Iwatsubo T.

Am J Pathol. 1998 Apr;152(4):879-84.

PMID:
9546347
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Early and persistent expression of phosphorylated α-synuclein in the enteric nervous system of A53T mutant human α-synuclein transgenic mice.

Bencsik A, Muselli L, Leboidre M, Lakhdar L, Baron T.

J Neuropathol Exp Neurol. 2014 Dec;73(12):1144-51. doi: 10.1097/NEN.0000000000000137.

PMID:
25383638
[PubMed - indexed for MEDLINE]
8.

Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

Kramer ML, Schulz-Schaeffer WJ.

J Neurosci. 2007 Feb 7;27(6):1405-10.

PMID:
17287515
[PubMed - indexed for MEDLINE]
Free Article
9.

Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.

Gu XL, Long CX, Sun L, Xie C, Lin X, Cai H.

Mol Brain. 2010 Apr 21;3:12. doi: 10.1186/1756-6606-3-12.

PMID:
20409326
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Aggregation of alpha-synuclein in the pathogenesis of Parkinson's disease.

Iwatsubo T.

J Neurol. 2003 Oct;250 Suppl 3:III11-4.

PMID:
14579119
[PubMed - indexed for MEDLINE]
11.

Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies.

Muntané G, Dalfó E, Martinez A, Ferrer I.

Neuroscience. 2008 Apr 9;152(4):913-23. doi: 10.1016/j.neuroscience.2008.01.030. Epub 2008 Feb 5.

PMID:
18343584
[PubMed - indexed for MEDLINE]
12.

Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA.

Bétemps D, Verchère J, Brot S, Morignat E, Bousset L, Gaillard D, Lakhdar L, Melki R, Baron T.

Acta Neuropathol Commun. 2014 Mar 13;2:29. doi: 10.1186/2051-5960-2-29.

PMID:
24624994
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A critical evaluation of current staging of alpha-synuclein pathology in Lewy body disorders.

Jellinger KA.

Biochim Biophys Acta. 2009 Jul;1792(7):730-40. doi: 10.1016/j.bbadis.2008.07.006. Epub 2008 Aug 5. Review.

PMID:
18718530
[PubMed - indexed for MEDLINE]
Free Article
14.

Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice.

Tanji K, Mori F, Mimura J, Itoh K, Kakita A, Takahashi H, Wakabayashi K.

Acta Neuropathol. 2010 Aug;120(2):145-54. doi: 10.1007/s00401-010-0676-z. Epub 2010 Mar 26.

PMID:
20339856
[PubMed - indexed for MEDLINE]
15.

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice.

Luk KC, Kehm VM, Zhang B, O'Brien P, Trojanowski JQ, Lee VM.

J Exp Med. 2012 May 7;209(5):975-86. doi: 10.1084/jem.20112457. Epub 2012 Apr 16.

PMID:
22508839
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.

Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8968-73.

PMID:
12084935
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation.

Huang Y, Chegini F, Chua G, Murphy K, Gai W, Halliday GM.

Transl Neurodegener. 2012 Jan 13;1(1):2. doi: 10.1186/2047-9158-1-2.

PMID:
23210740
[PubMed]
Free PMC Article
18.

The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia.

Schulz-Schaeffer WJ.

Acta Neuropathol. 2010 Aug;120(2):131-43. doi: 10.1007/s00401-010-0711-0. Epub 2010 Jun 20. Review.

PMID:
20563819
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Neuropathological spectrum of synucleinopathies.

Jellinger KA.

Mov Disord. 2003 Sep;18 Suppl 6:S2-12. Review.

PMID:
14502650
[PubMed - indexed for MEDLINE]
20.

Lentivirus mediated delivery of neurosin promotes clearance of wild-type α-synuclein and reduces the pathology in an α-synuclein model of LBD.

Spencer B, Michael S, Shen J, Kosberg K, Rockenstein E, Patrick C, Adame A, Masliah E.

Mol Ther. 2013 Jan;21(1):31-41. doi: 10.1038/mt.2012.66. Epub 2012 Apr 17.

PMID:
22508489
[PubMed - indexed for MEDLINE]
Free PMC Article

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