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Results: 1 to 20 of 173

1.

Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice.

Rothenberg ME, Nusse Y, Kalisky T, Lee JJ, Dalerba P, Scheeren F, Lobo N, Kulkarni S, Sim S, Qian D, Beachy PA, Pasricha PJ, Quake SR, Clarke MF.

Gastroenterology. 2012 May;142(5):1195-1205.e6. doi: 10.1053/j.gastro.2012.02.006. Epub 2012 Feb 11.

PMID:
22333952
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice.

King JB, von Furstenberg RJ, Smith BJ, McNaughton KK, Galanko JA, Henning SJ.

Am J Physiol Gastrointest Liver Physiol. 2012 Aug 15;303(4):G443-52. doi: 10.1152/ajpgi.00087.2012. Epub 2012 Jun 21.

PMID:
22723265
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay.

Wang F, Scoville D, He XC, Mahe MM, Box A, Perry JM, Smith NR, Lei NY, Davies PS, Fuller MK, Haug JS, McClain M, Gracz AD, Ding S, Stelzner M, Dunn JC, Magness ST, Wong MH, Martin MG, Helmrath M, Li L.

Gastroenterology. 2013 Aug;145(2):383-95.e1-21. doi: 10.1053/j.gastro.2013.04.050. Epub 2013 May 2.

PMID:
23644405
[PubMed - indexed for MEDLINE]
4.

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H.

Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28.

PMID:
21113151
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.

Heuberger J, Kosel F, Qi J, Grossmann KS, Rajewsky K, Birchmeier W.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3472-7. doi: 10.1073/pnas.1309342111. Epub 2014 Feb 18.

PMID:
24550486
[PubMed - indexed for MEDLINE]
6.

Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.

Kim TH, Escudero S, Shivdasani RA.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3932-7. doi: 10.1073/pnas.1113890109. Epub 2012 Feb 21.

PMID:
22355124
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Identification of stem cells in small intestine and colon by marker gene Lgr5.

Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H.

Nature. 2007 Oct 25;449(7165):1003-7. Epub 2007 Oct 14.

PMID:
17934449
[PubMed - indexed for MEDLINE]
8.

Sorting mouse jejunal epithelial cells with CD24 yields a population with characteristics of intestinal stem cells.

von Furstenberg RJ, Gulati AS, Baxi A, Doherty JM, Stappenbeck TS, Gracz AD, Magness ST, Henning SJ.

Am J Physiol Gastrointest Liver Physiol. 2011 Mar;300(3):G409-17. doi: 10.1152/ajpgi.00453.2010. Epub 2010 Dec 23.

PMID:
21183658
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny.

Yin X, Farin HF, van Es JH, Clevers H, Langer R, Karp JM.

Nat Methods. 2014 Jan;11(1):106-12. doi: 10.1038/nmeth.2737. Epub 2013 Dec 1.

PMID:
24292484
[PubMed - indexed for MEDLINE]
10.

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H.

Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29.

PMID:
19329995
[PubMed - indexed for MEDLINE]
11.

The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.

Gregorieff A, Stange DE, Kujala P, Begthel H, van den Born M, Korving J, Peters PJ, Clevers H.

Gastroenterology. 2009 Oct;137(4):1333-45.e1-3. doi: 10.1053/j.gastro.2009.06.044. Epub 2009 Jun 21.

PMID:
19549527
[PubMed - indexed for MEDLINE]
12.

Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine.

Shimizu H, Okamoto R, Ito G, Fujii S, Nakata T, Suzuki K, Murano T, Mizutani T, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M.

PeerJ. 2014 May 1;2:e370. doi: 10.7717/peerj.370. eCollection 2014.

PMID:
24860699
[PubMed]
Free PMC Article
13.

Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract.

Levin TG, Powell AE, Davies PS, Silk AD, Dismuke AD, Anderson EC, Swain JR, Wong MH.

Gastroenterology. 2010 Dec;139(6):2072-2082.e5. doi: 10.1053/j.gastro.2010.08.053. Epub 2010 Oct 19.

PMID:
20826154
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.

Pellegrinet L, Rodilla V, Liu Z, Chen S, Koch U, Espinosa L, Kaestner KH, Kopan R, Lewis J, Radtke F.

Gastroenterology. 2011 Apr;140(4):1230-1240.e1-7. doi: 10.1053/j.gastro.2011.01.005. Epub 2011 Jan 14.

PMID:
21238454
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Secretory cell hyperplasia and defects in Notch activity in a mouse model of leukocyte adhesion deficiency type II.

Waterhouse CC, Johnson S, Phillipson M, Zbytnuik L, Petri B, Kelly M, Lowe JB, Kubes P.

Gastroenterology. 2010 Mar;138(3):1079-90.e1-5. doi: 10.1053/j.gastro.2009.10.049. Epub 2009 Nov 10.

PMID:
19900444
[PubMed - indexed for MEDLINE]
16.

Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells.

Farin HF, Van Es JH, Clevers H.

Gastroenterology. 2012 Dec;143(6):1518-1529.e7. doi: 10.1053/j.gastro.2012.08.031. Epub 2012 Aug 23.

PMID:
22922422
[PubMed - indexed for MEDLINE]
17.

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.

Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G.

Dev Biol. 2009 Jul 1;331(1):58-67. doi: 10.1016/j.ydbio.2009.04.020. Epub 2009 Apr 24.

PMID:
19394326
[PubMed - indexed for MEDLINE]
Free Article
18.

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.

Schepers AG, Snippert HJ, Stange DE, van den Born M, van Es JH, van de Wetering M, Clevers H.

Science. 2012 Aug 10;337(6095):730-5. doi: 10.1126/science.1224676. Epub 2012 Aug 1.

PMID:
22855427
[PubMed - indexed for MEDLINE]
Free Article
19.

Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation.

Feng Y, Sentani K, Wiese A, Sands E, Green M, Bommer GT, Cho KR, Fearon ER.

Am J Pathol. 2013 Aug;183(2):493-503. doi: 10.1016/j.ajpath.2013.04.013. Epub 2013 Jun 13.

PMID:
23769888
[PubMed - indexed for MEDLINE]
Free Article
20.

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

VanDussen KL, Carulli AJ, Keeley TM, Patel SR, Puthoff BJ, Magness ST, Tran IT, Maillard I, Siebel C, Kolterud Å, Grosse AS, Gumucio DL, Ernst SA, Tsai YH, Dempsey PJ, Samuelson LC.

Development. 2012 Feb;139(3):488-97. doi: 10.1242/dev.070763. Epub 2011 Dec 21.

PMID:
22190634
[PubMed - indexed for MEDLINE]
Free PMC Article

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