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Items: 1 to 20 of 142

1.

Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis.

Müller U, Piehler D, Stenzel W, Köhler G, Frey O, Held J, Grahnert A, Richter T, Eschke M, Kamradt T, Brombacher F, Alber G.

Mucosal Immunol. 2012 May;5(3):299-310. doi: 10.1038/mi.2012.9. Epub 2012 Feb 15.

PMID:
22333910
2.

Abrogation of IL-4 receptor-α-dependent alternatively activated macrophages is sufficient to confer resistance against pulmonary cryptococcosis despite an ongoing T(h)2 response.

Müller U, Stenzel W, Piehler D, Grahnert A, Protschka M, Köhler G, Frey O, Held J, Richter T, Eschke M, Kamradt T, Brombacher F, Alber G.

Int Immunol. 2013 Aug;25(8):459-70. doi: 10.1093/intimm/dxt003. Epub 2013 Mar 26.

3.

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

Radwanska M, Cutler AJ, Hoving JC, Magez S, Holscher C, Bohms A, Arendse B, Kirsch R, Hunig T, Alexander J, Kaye P, Brombacher F.

PLoS Pathog. 2007 May 11;3(5):e68.

4.

T1/ST2 promotes T helper 2 cell activation and polyfunctionality in bronchopulmonary mycosis.

Piehler D, Grahnert A, Eschke M, Richter T, Köhler G, Stenzel W, Alber G.

Mucosal Immunol. 2013 Mar;6(2):405-14. doi: 10.1038/mi.2012.84. Epub 2012 Sep 19.

PMID:
22990621
5.

Role of IFN-gamma in regulating T2 immunity and the development of alternatively activated macrophages during allergic bronchopulmonary mycosis.

Arora S, Hernandez Y, Erb-Downward JR, McDonald RA, Toews GB, Huffnagle GB.

J Immunol. 2005 May 15;174(10):6346-56.

6.

Th2 but not Th1 immune bias results in altered lung functions in a murine model of pulmonary Cryptococcus neoformans infection.

Jain AV, Zhang Y, Fields WB, McNamara DA, Choe MY, Chen GH, Erb-Downward J, Osterholzer JJ, Toews GB, Huffnagle GB, Olszewski MA.

Infect Immun. 2009 Dec;77(12):5389-99. doi: 10.1128/IAI.00809-09. Epub 2009 Sep 14.

7.

B cells that produce immunoglobulin E mediate colitis in BALB/c mice.

Hoving JC, Kirstein F, Nieuwenhuizen NE, Fick LC, Hobeika E, Reth M, Brombacher F.

Gastroenterology. 2012 Jan;142(1):96-108. doi: 10.1053/j.gastro.2011.09.044. Epub 2011 Oct 6.

PMID:
21983080
8.

A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis.

Müller U, Stenzel W, Köhler G, Polte T, Blessing M, Mann A, Piehler D, Brombacher F, Alber G.

J Infect Dis. 2008 Dec 1;198(11):1714-21. doi: 10.1086/593068.

9.

IL-4Ralpha responsiveness of non-CD4 T cells contributes to resistance in schistosoma mansoni infection in pan-T cell-specific IL-4Ralpha-deficient mice.

Dewals B, Hoving JC, Leeto M, Marillier RG, Govender U, Cutler AJ, Horsnell WG, Brombacher F.

Am J Pathol. 2009 Aug;175(2):706-16. doi: 10.2353/ajpath.2009.090137. Epub 2009 Jul 23.

10.

Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99.

Zhang Y, Wang F, Tompkins KC, McNamara A, Jain AV, Moore BB, Toews GB, Huffnagle GB, Olszewski MA.

Am J Pathol. 2009 Dec;175(6):2489-500. doi: 10.2353/ajpath.2009.090530. Epub 2009 Nov 5.

11.

Deletion of IL-4 receptor alpha on dendritic cells renders BALB/c mice hypersusceptible to Leishmania major infection.

Hurdayal R, Nieuwenhuizen NE, Revaz-Breton M, Smith L, Hoving JC, Parihar SP, Reizis B, Brombacher F.

PLoS Pathog. 2013 Oct;9(10):e1003699. doi: 10.1371/journal.ppat.1003699. Epub 2013 Oct 24.

12.

Interleukin-4-promoted T helper 2 responses enhance Nippostrongylus brasiliensis-induced pulmonary pathology.

Mearns H, Horsnell WG, Hoving JC, Dewals B, Cutler AJ, Kirstein F, Myburgh E, Arendse B, Brombacher F.

Infect Immun. 2008 Dec;76(12):5535-42. doi: 10.1128/IAI.00210-08. Epub 2008 Sep 22.

13.

Stimulation via Toll-like receptor 9 reduces Cryptococcus neoformans-induced pulmonary inflammation in an IL-12-dependent manner.

Edwards L, Williams AE, Krieg AM, Rae AJ, Snelgrove RJ, Hussell T.

Eur J Immunol. 2005 Jan;35(1):273-81.

14.

IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni.

Linehan SA, Coulson PS, Wilson RA, Mountford AP, Brombacher F, Martínez-Pomares L, Gordon S.

Lab Invest. 2003 Aug;83(8):1223-31.

PMID:
12920251
15.

Effect of cytokine interplay on macrophage polarization during chronic pulmonary infection with Cryptococcus neoformans.

Arora S, Olszewski MA, Tsang TM, McDonald RA, Toews GB, Huffnagle GB.

Infect Immun. 2011 May;79(5):1915-26. doi: 10.1128/IAI.01270-10. Epub 2011 Mar 7.

16.

Comparative roles of IL-4, IL-13, and IL-4Ralpha in dendritic cell maturation and CD4+ Th2 cell function.

Webb DC, Cai Y, Matthaei KI, Foster PS.

J Immunol. 2007 Jan 1;178(1):219-27.

17.

IL-4Ralpha-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness.

Dewals BG, Marillier RG, Hoving JC, Leeto M, Schwegmann A, Brombacher F.

PLoS Negl Trop Dis. 2010 May 18;4(5):e689. doi: 10.1371/journal.pntd.0000689.

18.

Distinct roles for IL-4 and IL-10 in regulating T2 immunity during allergic bronchopulmonary mycosis.

Hernandez Y, Arora S, Erb-Downward JR, McDonald RA, Toews GB, Huffnagle GB.

J Immunol. 2005 Jan 15;174(2):1027-36.

19.

TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis.

Leeto M, Herbert DR, Marillier R, Schwegmann A, Fick L, Brombacher F.

Am J Pathol. 2006 Nov;169(5):1701-12.

20.

IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.

Müller U, Stenzel W, Köhler G, Werner C, Polte T, Hansen G, Schütze N, Straubinger RK, Blessing M, McKenzie AN, Brombacher F, Alber G.

J Immunol. 2007 Oct 15;179(8):5367-77.

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