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Results: 1 to 20 of 124

1.

Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.

Song J, Teplova M, Ishibe-Murakami S, Patel DJ.

Science. 2012 Feb 10;335(6069):709-12. doi: 10.1126/science.1214453.

PMID:
22323818
[PubMed - indexed for MEDLINE]
Free Article
2.

Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.

Song J, Rechkoblit O, Bestor TH, Patel DJ.

Science. 2011 Feb 25;331(6020):1036-40. doi: 10.1126/science.1195380. Epub 2010 Dec 16.

PMID:
21163962
[PubMed - indexed for MEDLINE]
Free Article
3.

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism.

Arita K, Ariyoshi M, Tochio H, Nakamura Y, Shirakawa M.

Nature. 2008 Oct 9;455(7214):818-21. doi: 10.1038/nature07249. Epub 2008 Sep 3.

PMID:
18772891
[PubMed - indexed for MEDLINE]
4.

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix.

Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X.

Nature. 2008 Oct 9;455(7214):826-9. doi: 10.1038/nature07280. Epub 2008 Sep 3.

PMID:
18772888
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase.

Bashtrykov P, Ragozin S, Jeltsch A.

FEBS Lett. 2012 Jun 21;586(13):1821-3. doi: 10.1016/j.febslet.2012.05.026. Epub 2012 May 26.

PMID:
22641038
[PubMed - indexed for MEDLINE]
Free Article
7.

Molecular biology. Preference by exclusion.

Godley LA, Mondragón A.

Science. 2011 Feb 25;331(6020):1017-8. doi: 10.1126/science.1202090. No abstract available.

PMID:
21350155
[PubMed - indexed for MEDLINE]
8.

Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain.

Bashtrykov P, Jankevicius G, Smarandache A, Jurkowska RZ, Ragozin S, Jeltsch A.

Chem Biol. 2012 May 25;19(5):572-8. doi: 10.1016/j.chembiol.2012.03.010.

PMID:
22633409
[PubMed - indexed for MEDLINE]
Free Article
9.

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.

Avvakumov GV, Walker JR, Xue S, Li Y, Duan S, Bronner C, Arrowsmith CH, Dhe-Paganon S.

Nature. 2008 Oct 9;455(7214):822-5. doi: 10.1038/nature07273. Epub 2008 Sep 3.

PMID:
18772889
[PubMed - indexed for MEDLINE]
10.

Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).

Takeshita K, Suetake I, Yamashita E, Suga M, Narita H, Nakagawa A, Tajima S.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9055-9. doi: 10.1073/pnas.1019629108. Epub 2011 Apr 25.

PMID:
21518897
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

Valinluck V, Sowers LC.

Cancer Res. 2007 Feb 1;67(3):946-50.

PMID:
17283125
[PubMed - indexed for MEDLINE]
Free Article
12.

Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase.

Vilkaitis G, Suetake I, Klimasauskas S, Tajima S.

J Biol Chem. 2005 Jan 7;280(1):64-72. Epub 2004 Oct 27.

PMID:
15509558
[PubMed - indexed for MEDLINE]
Free Article
13.

Mammalian DNA (cytosine-5) methyltransferases and their expression.

Pradhan S, Esteve PO.

Clin Immunol. 2003 Oct;109(1):6-16. Review.

PMID:
14585271
[PubMed - indexed for MEDLINE]
14.

The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites.

Hermann A, Goyal R, Jeltsch A.

J Biol Chem. 2004 Nov 12;279(46):48350-9. Epub 2004 Aug 31.

PMID:
15339928
[PubMed - indexed for MEDLINE]
Free Article
15.

Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites.

Gowher H, Jeltsch A.

J Mol Biol. 2001 Jun 22;309(5):1201-8. Erratum in: J Mol Biol 2001 Jul 20;310(4):951.

PMID:
11399089
[PubMed - indexed for MEDLINE]
16.

Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1.

Kimura H, Shiota K.

J Biol Chem. 2003 Feb 14;278(7):4806-12. Epub 2002 Dec 6.

PMID:
12473678
[PubMed - indexed for MEDLINE]
Free Article
17.

The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.

Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A.

J Biol Chem. 2014 Feb 14;289(7):4106-15. doi: 10.1074/jbc.M113.528893. Epub 2013 Dec 24.

PMID:
24368767
[PubMed - indexed for MEDLINE]
18.

Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.

Sheikhnejad G, Brank A, Christman JK, Goddard A, Alvarez E, Ford H Jr, Marquez VE, Marasco CJ, Sufrin JR, O'gara M, Cheng X.

J Mol Biol. 1999 Feb 5;285(5):2021-34.

PMID:
9925782
[PubMed - indexed for MEDLINE]
19.

Functional CpG methylation system in a social insect.

Wang Y, Jorda M, Jones PL, Maleszka R, Ling X, Robertson HM, Mizzen CA, Peinado MA, Robinson GE.

Science. 2006 Oct 27;314(5799):645-7.

PMID:
17068262
[PubMed - indexed for MEDLINE]
Free Article
20.

Hybrid mouse-prokaryotic DNA (cytosine-5) methyltransferases retain the specificity of the parental C-terminal domain.

Pradhan S, Roberts RJ.

EMBO J. 2000 May 2;19(9):2103-14.

PMID:
10790376
[PubMed - indexed for MEDLINE]
Free PMC Article

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