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Results: 1 to 20 of 263

1.

Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway.

Kong L, Schäfer G, Bu H, Zhang Y, Zhang Y, Klocker H.

Carcinogenesis. 2012 Apr;33(4):751-9. doi: 10.1093/carcin/bgs022. Epub 2012 Feb 1.

PMID:
22301279
[PubMed - indexed for MEDLINE]
Free Article
2.

Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion.

Shukla S, Maclennan GT, Hartman DJ, Fu P, Resnick MI, Gupta S.

Int J Cancer. 2007 Oct 1;121(7):1424-32.

PMID:
17551921
[PubMed - indexed for MEDLINE]
3.

IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells.

Ma J, Sawai H, Matsuo Y, Ochi N, Yasuda A, Takahashi H, Wakasugi T, Funahashi H, Sato M, Takeyama H.

J Surg Res. 2010 May 1;160(1):90-101. doi: 10.1016/j.jss.2008.08.016. Epub 2008 Sep 13.

PMID:
19560785
[PubMed - indexed for MEDLINE]
4.

TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer.

Shih MC, Chen JY, Wu YC, Jan YH, Yang BM, Lu PJ, Cheng HC, Huang MS, Yang CJ, Hsiao M, Lai JM.

Oncogene. 2012 May 10;31(19):2389-400. doi: 10.1038/onc.2011.419. Epub 2011 Sep 26.

PMID:
21996732
[PubMed - indexed for MEDLINE]
5.
6.

PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway.

Tian T, Nan KJ, Guo H, Wang WJ, Ruan ZP, Wang SH, Liang X, Lu CX.

Oncol Rep. 2010 Jun;23(6):1593-600.

PMID:
20428814
[PubMed - indexed for MEDLINE]
7.

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.

PMID:
16854453
[PubMed - indexed for MEDLINE]
8.

PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling.

Conley-LaComb MK, Saliganan A, Kandagatla P, Chen YQ, Cher ML, Chinni SR.

Mol Cancer. 2013 Jul 31;12(1):85. doi: 10.1186/1476-4598-12-85.

PMID:
23902739
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway.

Ni J, Wen X, Yao J, Chang HC, Yin Y, Zhang M, Xie S, Chen M, Simons B, Chang P, di Sant'Agnese A, Messing EM, Yeh S.

Cancer Res. 2005 Nov 1;65(21):9807-16.

PMID:
16267002
[PubMed - indexed for MEDLINE]
Free Article
10.

Insulin-like growth factor-type 1 receptor inhibitor NVP-AEW541 enhances radiosensitivity of PTEN wild-type but not PTEN-deficient human prostate cancer cells.

Isebaert SF, Swinnen JV, McBride WH, Haustermans KM.

Int J Radiat Oncol Biol Phys. 2011 Sep 1;81(1):239-47. doi: 10.1016/j.ijrobp.2011.03.030.

PMID:
21816290
[PubMed - indexed for MEDLINE]
11.

Effects of adipocytes on the proliferation and differentiation of prostate cancer cells in a 3-D culture model.

Kaneko A, Satoh Y, Tokuda Y, Fujiyama C, Udo K, Uozumi J.

Int J Urol. 2010 Apr;17(4):369-76. doi: 10.1111/j.1442-2042.2010.02472.x.

PMID:
20409231
[PubMed - indexed for MEDLINE]
12.

Serotonin activates MAP kinase and PI3K/Akt signaling pathways in prostate cancer cell lines.

Dizeyi N, Hedlund P, Bjartell A, Tinzl M, Austild-Taskén K, Abrahamsson PA.

Urol Oncol. 2011 Jul-Aug;29(4):436-45. doi: 10.1016/j.urolonc.2009.09.013. Epub 2009 Nov 19.

PMID:
19926313
[PubMed - indexed for MEDLINE]
13.

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.

Biol Pharm Bull. 2010;33(11):1828-34.

PMID:
21048307
[PubMed - indexed for MEDLINE]
Free Article
14.

Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells.

Ohigashi T, Mizuno R, Nakashima J, Marumo K, Murai M.

Prostate. 2005 Jan 1;62(1):61-8.

PMID:
15389810
[PubMed - indexed for MEDLINE]
15.

Influence of zinc deficiency on Akt-Mdm2-p53 and Akt-p21 signaling axes in normal and malignant human prostate cells.

Han CT, Schoene NW, Lei KY.

Am J Physiol Cell Physiol. 2009 Nov;297(5):C1188-99. doi: 10.1152/ajpcell.00042.2009. Epub 2009 Aug 5.

PMID:
19657064
[PubMed - indexed for MEDLINE]
Free Article
16.

Knockdown of AGR2 induces cellular senescence in prostate cancer cells.

Hu Z, Gu Y, Han B, Zhang J, Li Z, Tian K, Young CY, Yuan H.

Carcinogenesis. 2012 Jun;33(6):1178-86. doi: 10.1093/carcin/bgs141. Epub 2012 Mar 31.

PMID:
22467239
[PubMed - indexed for MEDLINE]
Free Article
17.

Inhibition of the phosphatidylinositol 3'-kinase pathway promotes autocrine Fas-induced death of phosphatase and tensin homologue-deficient prostate cancer cells.

Bertram J, Peacock JW, Tan C, Mui AL, Chung SW, Gleave ME, Dedhar S, Cox ME, Ong CJ.

Cancer Res. 2006 May 1;66(9):4781-8.

PMID:
16651432
[PubMed - indexed for MEDLINE]
Free Article
18.

Loss of BRCA2 promotes prostate cancer cell invasion through up-regulation of matrix metalloproteinase-9.

Moro L, Arbini AA, Yao JL, di Sant'Agnese PA, Marra E, Greco M.

Cancer Sci. 2008 Mar;99(3):553-63. doi: 10.1111/j.1349-7006.2007.00719.x. Epub 2007 Dec 27.

PMID:
18167127
[PubMed - indexed for MEDLINE]
19.

Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival.

Wegiel B, Bjartell A, Culig Z, Persson JL.

Int J Cancer. 2008 Apr 1;122(7):1521-9.

PMID:
18027847
[PubMed - indexed for MEDLINE]
20.

PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression.

Huang H, Cheville JC, Pan Y, Roche PC, Schmidt LJ, Tindall DJ.

J Biol Chem. 2001 Oct 19;276(42):38830-6. Epub 2001 Aug 8.

PMID:
11495901
[PubMed - indexed for MEDLINE]
Free Article

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